On the Influence of Diurnal and Subdiurnal Signals in the Normal Vector on Large Ring Laser Gyroscope Observations

The ring laser gyroscope (RLG) technique has been investigated for over 20 years as a potential complement to space geodetic techniques in measuring Earth rotation. However, RLGs are also sensitive to changes in their terrestrial orientation. Therefore in this paper, we review how the high-frequency band (i.e. signals shorter than 0.5 cycle per day) of the known phenomena causing site deformation contribute to the RLG observable, the Sagnac frequency. We study the impact of solid Earth tides, ocean tidal loading and non-tidal loading phenomena (atmospheric pressure loading and continental hydrosphere loading). Also, we evaluate the differences between available models of the phenomena and the importance of the Love numbers used in modeling the impact of solid Earth tides. Finally, we compare modeled variations in the instrument orientation with the ones observed with a tiltmeter. Our results prove that at the present accuracy of the RLG technique, solid Earth tides and ocean tidal loading effects have significant effect on RLG measurements, and continental hydrosphere loading can be actually neglected. Regarding the atmospheric loading model, its application might introduce some undesired signals. We also show that discrepancies arising from the use of different models can be neglected, and there is almost no impact arising from the use of different Love numbers. Finally, we discuss differences between data reduced with tiltmeter observations and these reduced with modeled signal, and potential causes of this discrepancies

Rare presentation of a benign smooth muscle tumour of venous wall

Deep veins thrombosis is commonly encountered in clinical practice. The reasons and risk factors are well known. Unusual conditions leading to complete obstruction of larger veins are rarely anticipated. A 34-years-old woman was treated in our hospital because of segmental thrombosis of her right common femoral vein. Color duplex Doppler revealed a solitary thrombus 5 centimeters in lengths narrowing it by 80–90%. During emergency operation a small tumour in the orifice of greater saphenous vein was found with adhering thrombus. Segmental thrombosis of large vein can be connected with an occult underlying pathology. Color duplex Doppler alone does not allow complete evaluation of such problems

Diversity and transmission of Aleutian mink disease virus in feral and farmed American mink and native mustelids

Aleutian mink disease virus (AMDV), which causes Aleutian disease, is widely spread both in farmed mink and wild mustelids. However, only limited data are available on the role of wild animals in AMDV transmission and spread. Our aim was to shed light on AMDV transmission among wild mustelids and estimate the effect of intense farming practices on the virus circulation by studying AMDV prevalence and genetic diversity among wild mustelids in Poland. We compared AMDV seroprevalence and proportion of PCR-positive individuals in American mink, polecats, otters, stone martens, and pine martens and used the phylogenetic analysis of the NS1 region to study transmission. In addition, we used a metagenomic approach to sequence complete AMDV genomes from tissue samples. In eastern Poland, AMDV seroprevalence in wild mustelids varied from 22 per cent in otters to 62 per cent and 64 per cent in stone martens and feral mink, respectively. All studied antibody-positive mink were also PCR positive, whereas only 10, 15, and 18 per cent of antibody-positive polecats, pine martens, and stone martens, respectively, were PCR positive, suggesting lower virus persistence among these animal species as compared to feral mink. In phylogenetic analysis, most sequences from feral mink formed region-specific clusters that have most likely emerged through multiple introductions of AMDV to feral mink population over decades. However, virus spread between regions was also observed. Virus sequences derived from farmed and wild animals formed separate subclusters in the phylogenetic tree, and no signs of recent virus transmission between farmed and wild animals were observed despite the frequent inflow of farmed mink escapees to wild populations. These results provide new information about the role of different mustelid species in AMDV transmission and about virus circulation among the wild mustelids. In addition, we pinpoint gaps of knowledge, where more studies are needed to achieve a comprehensive picture of AMDV transmission.Peer reviewe

Transfermoral aortic valve implantation using self-expanding New Valve Technology (NVT) Allegra bioprosthesis: A pilot prospective study

Background: Transcatheter aortic valve implantation (TAVI) has become a standard therapeutic option for patients with severe aortic stenosis (AS) at high cardiac surgical risk. The aim of the NAUTILUS study was to investigate the safety and performance of the New Valve Technology (NVT) Allegra bioprosthesis in high-risk patients undergoing TAVI. Methods: Twenty seven patients with severe, symptomatic AS at high surgical risk were prospectively enrolled, who underwent treatment using the novel self-expanding NVT Allegra bioprosthesis via transfemoral approach (TF-TAVI). The primary end-point was all-cause mortality at 30 days. Results: Patients were elderly (83 years, range 75–89 years), and predominantly female (70.4%, n = 19). All patients were deemed to be at high surgical risk, with a mean logistic EuroSCORE of 12.4% (range, 2.8–31.8%). The bioprosthesis was successfully implanted in 96% of the cases (n = 25). The echocardiographic assessment confirmed good hemodynamic profile after implantation of the NVT Allegra bioprosthesis. Complications included cardiac tamponade (4%, n = 1) and the need for permanent pacemaker implantation (8%, n = 2). The analysis of procedural aspects showed a short learning effect related to the precise placement of the valve. A significant improvement in clinical symptoms were observed, and no patients died in-hospital or within 30 days of post-discharge observation. Conclusions: This prospective observation shows that the NVT Allegra bioprosthesis was associated with a satisfactory safety profile and a remarkable hemodynamic performance after implantation

The effect of nest site on the nesting success of the Coot Fulica atra

The nesting success of Coots (Fulica atra) breeding at lakes and small inland water bod-ies in the Mazurian Lakeland, Poland, was estimated in 2008 and 2009. Mean nesting suc-cess, indicated by hatching, was 75%; it was highest at lakes in the vicinity of built-up areas (86%), moderate at small inland water bodies (69%) and lowest at lakes far from hu-man settlements (44%). Nesting success improved with decreasing distance to open wa-ter. Our results suggest that small inland water bodies and built-up areas along lake banks may serve as Coot refuges, acting as safeguards against predation, especially by the American Mink

Pedestrian Safety at Midblock Crossings on Dual Carriageway Roads in Polish Cities

Road crossings across two or more lanes in one direction are particularly dangerous due to limited sight distance and high vehicle speeds. To improve their safety, road authorities should provide safety treatments. These may include additional measures to reduce speed and narrow the road cross-section and the introduction of active pedestrian crossings. Equipped with flashing lights activated automatically when a pedestrian is detected, the crossings are painted red and have an anti-skid surface on approaches. The article presents an analysis of road user behaviour at pedestrian crossings on dual carriageways with a varying provision of road safety measures in some Polish cities. It also evaluates the effectiveness of the measures over time. The study was conducted before, immediately after and one year after the additional signage was introduced. The evaluation is based on how vehicle speeds changed before the pedestrian crossing, how pedestrians behaved versus the vehicle and their readiness to cross the street. The number of conflicts on selected crossings was also evaluated. The safety treatments under analysis were found to be less effective than the traditional pedestrian safety measures such as speed cushions or roads narrowed to one lane. This suggests that if used on dual carriageways the measures should only be temporary and should ultimately be replaced with traffic lights or a grade separated solution (a footbridge or tunnel) on exits from urban areas. No clear-cut conclusions about pedestrian safety can be drawn based on the traffic conflicts in question. The article is divided into the following sections: introduction with a review of the literature on pedestrian and driver behaviour studies at pedestrian crossings, including midblock crossings and dual carriageways; a description of the research method and test sites, the results, discussion of the results and conclusion

Pedestrian Safety at Midblock Crossings on Dual Carriageway Roads in Polish Cities

Road crossings across two or more lanes in one direction are particularly dangerous due to limited sight distance and high vehicle speeds. To improve their safety, road authorities should provide safety treatments. These may include additional measures to reduce speed and narrow the road cross-section and the introduction of active pedestrian crossings. Equipped with flashing lights activated automatically when a pedestrian is detected, the crossings are painted red and have an anti-skid surface on approaches. The article presents an analysis of road user behaviour at pedestrian crossings on dual carriageways with a varying provision of road safety measures in some Polish cities. It also evaluates the effectiveness of the measures over time. The study was conducted before, immediately after and one year after the additional signage was introduced. The evaluation is based on how vehicle speeds changed before the pedestrian crossing, how pedestrians behaved versus the vehicle and their readiness to cross the street. The number of conflicts on selected crossings was also evaluated. The safety treatments under analysis were found to be less effective than the traditional pedestrian safety measures such as speed cushions or roads narrowed to one lane. This suggests that if used on dual carriageways the measures should only be temporary and should ultimately be replaced with traffic lights or a grade separated solution (a footbridge or tunnel) on exits from urban areas. No clear-cut conclusions about pedestrian safety can be drawn based on the traffic conflicts in question. The article is divided into the following sections: introduction with a review of the literature on pedestrian and driver behaviour studies at pedestrian crossings, including midblock crossings and dual carriageways; a description of the research method and test sites, the results, discussion of the results and conclusion

CheckMyBlob evaluation data set (TAMC)

A data set of ligands used to evaluate the CheckMyBlob method, described in the Kowiel et al. paper "Automatic recognition of ligands in electron density by machine learning methods". This data set attempts to repeat the experimental setup from Terwilliger et al. described in "Ligand identification using electron-density map correlations". It consists of ligands from X-ray diffraction experiments with 6–150 non-H atoms. Connected PDB ligands were labeled as single alphabetically ordered strings of hetero-compound codes, whereas unknown species, water molecules, standard amino acids, and nucleotides were excluded. Finally, the data set was limited to 200 most popular ligands. The resulting data set consisted of 161,758 examples with individual ligand counts ranging from 36,535 examples for GOL (glycerol) to 114 for LMG (1,2-distearoyl-monogalactosyl-diglyceride). For machine learning (classification) purposes, the target attribute is: res_name