148 research outputs found

    Dependence of flood peaks and volumes in modeled discharge time series: effect of different uncertainty sources

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    Flood estimates needed for designing efficient and cost-effective flood protection structures are usually derived using observed peak discharges. This approach neglects, firstly, that floods are characterized not only by peak discharge but also by flood volume, and, secondly, that these characteristics are subject to modifications under climate and land use changes. Bivariate flood frequency analysis based on simulated discharge time series makes it possible to consider both flood peak and flood volume in design flood estimation. Further, this approach considers changes in discharge characteristics by using discharge series generated from climate time series used as an input for a hydrological model. Such series are usually not available at an hourly resolution but at a certain aggregation level (e.g. 24 h) and might not perfectly represent observed precipitation distributions. In this study, we therefore investigate how the aggregation and distribution of precipitation series and discharge distribution affect flood peaks and volumes and their dependence. We propose a framework for assessing the uncertainty in bivariate design flood estimates that is caused by different factors in the modeling chain, which consists of precipitation-discharge modeling, flood event sampling, and bivariate flood frequency analysis. The uncertainty sources addressed are precipitation aggregation and distribution, parameter and model uncertainty, and discharge resolution. Our results show that all of these uncertainty sources are relevant for design flood estimation and that the importance of the individual uncertainty sources is catchment dependent. Our results also demonstrate that substantial uncertainty is introduced already in the first step of the model chain because commonly used calibration procedures do not take into account the reproduction of flood volumes. Researchers should be aware of such deficiencies when performing bivariate flood frequency analysis on modeled discharge time series and should aim to tailor model calibration procedures to the problem at hand

    Elasticity curves describe streamflow sensitivity to precipitation across the entire flow distribution

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    Streamflow elasticity is the ratio of the expected percentage change in streamflow for a 1% change in precipitation; a simple approximation of how responsive a river is to precipitation. Typically estimated for the annual average streamflow, we propose a new concept in which streamflow elasticity is estimated for multiple percentiles across the full range of the streamflow. This “elasticity curve” can then be used to develop a more complete depiction of how streamflow responds to climate. Representing elasticity as a curve which reflects the range of responses across the distribution of streamflow within a given time period, instead of as a single point estimate, provides a novel lens through which we can interpret hydrological behaviour. As an example, we calculate elasticity curves for 805 catchments in the United States and then cluster them according to their shape. This results in three distinct elasticity curve types which characterize the streamflow-precipitation relationship at the annual and seasonal timescales. Through this, we demonstrate that elasticity estimated from the central summary of streamflow, e.g. the annual median, does not provide a complete picture of streamflow sensitivity. Further, we show that elasticity curve shape, i.e. the response of different flow percentiles relative to one another in one catchment, can be interpreted separately from between-catchment variation in the average magnitude of streamflow change associated with a one percent change in precipitation. Finally, we find that available water storage is likely the key control which determines curve shape

    „Warm brothers“ on trial: The image of the male homosexual as constructed by homosexuals themselves and by others during the NS period in Austria

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    Abstract: Based on the court records of 1,500 men accused of homosexual conduct from the Viennese Civil Courts and Military Courts from Austria under National Socialist rule, a sample of 434 men was selected randomly and analyzed quantitatively. The article aims to provide the most comprehensive survey hitherto of the self-perceptions of male homosexuals and of the ways they were perceived by others in that period. The descriptions of identities that were used in the selected case histories by the persecuting authorities and as self-definition by the victims were collected and interpreted in accordance with international discussions that have taken place in historical gender and LGBTIQ Studies. Additionally, the social background of the persecuted men and information on the structure and extent of the persecution were analyzed.Abstract: Based on the court records of 1,500 men accused of homosexual conduct from the Viennese Civil Courts and Military Courts from Austria under National Socialist rule, a sample of 434 men was selected randomly and analyzed quantitatively. The article aims to provide the most comprehensive survey hitherto of the self-perceptions of male homosexuals and of the ways they were perceived by others in that period. The descriptions of identities that were used in the selected case histories by the persecuting authorities and as self-definition by the victims were collected and interpreted in accordance with international discussions that have taken place in historical gender and LGBTIQ Studies. Additionally, the social background of the persecuted men and information on the structure and extent of the persecution were analyzed

    Spatial sensitivity of river flooding to changes in climate and land cover through explainable AI

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    Explaining the spatially variable impacts of flood-generating mechanisms is a longstanding challenge in hydrology, with increasing and decreasing temporal flood trends often found in close regional proximity. Here, we develop a machine learning-informed approach to unravel the drivers of seasonal flood magnitude and explain the spatial variability of their effects in a temperate climate. We employ 11 observed meteorological and land cover (LC) time series variables alongside 8 static catchment attributes to model flood magnitude in 1,268 catchments across Great Britain over four decades. We then perform a sensitivity analysis to assess how a 10% increase in precipitation, a 1°C rise in air temperature, or a 10 percentage point increase in urban or forest LC may affect flood magnitude in catchments with varying characteristics. Our simulations show that increasing precipitation and urbanization both tend to amplify flood magnitude significantly more in catchments with high baseflow contribution and low runoff ratio, which tend to have lower values of specific discharge on average. In contrast, rising air temperature (in the absence of changing precipitation) decreases flood magnitudes, with the largest effects in dry catchments with low baseflow index. Afforestation also tends to decrease floods more in catchments with low groundwater contribution, and in dry catchments in the summer. Our approach may be used to further disentangle the joint effects of multiple flood drivers in individual catchments

    Future shifts in extreme flow regimes in Alpine regions

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    Extreme low and high flows can have negative economic, social, and ecological effects and are expected to become more severe in many regions due to climate change. Besides low and high flows, the whole flow regime, i.e., annual hydrograph comprised of monthly mean flows, is subject to changes. Knowledge on future changes in flow regimes is important since regimes contain information on both extremes and conditions prior to the dry and wet seasons. Changes in individual low- and high-flow characteristics as well as flow regimes under mean conditions have been thoroughly studied. In contrast, little is known about changes in extreme flow regimes. We here propose two methods for the estimation of extreme flow regimes and apply them to simulated discharge time series for future climate conditions in Switzerland. The first method relies on frequency analysis performed on annual flow duration curves. The second approach performs frequency analysis of the discharge sums of a large set of stochastically generated annual hydrographs. Both approaches were found to produce similar 100-year regime estimates when applied to a data set of 19 hydrological regions in Switzerland. Our results show that changes in both extreme low- and high-flow regimes for rainfall-dominated regions are distinct from those in melt-dominated regions. In rainfall-dominated regions, the minimum discharge of low-flow regimes decreases by up to 50 %, whilst the reduction is 25 % for high-flow regimes. In contrast, the maximum discharge of low- and high-flow regimes increases by up to 50 %. In melt-dominated regions, the changes point in the other direction than those in rainfall-dominated regions. The minimum and maximum discharges of extreme regimes increase by up to 100 % and decrease by less than 50  %, respectively. Our findings provide guidance in water resource planning and management and the extreme regime estimates are a valuable basis for climate impact studies

    IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

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    Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant desmoplastic reaction driven by pancreatic stellate cells (PSCs) that contributes to tumor progression. Here we sought to characterize the interactions between pancreatic cancer cells (PCCs) and PSCs that affect the inflammatory and immune response in pancreatic tumors. Conditioned media from mono- and cocultures of PSCs and PCCs were assayed for expression of cytokines and growth factors. IP-10/CXCL10 was the most highly induced chemokine in coculture of PSCs and PCCs. Its expression was induced in the PSCs by PCCs. IP-10 was elevated in human PDAC specimens, and positively correlated with high stroma content. Furthermore, gene expression of IP-10 and its receptor CXCR3 were significantly associated with the intratumoral presence of regulatory T cells (Tregs). In an independent cohort of 48 patients with resectable pancreatic ductal adenocarcinoma, high IP-10 expression levels correlated with decreased median overall survival. Finally, IP-10 stimulated the ex vivo recruitment of CXCR3+ effector T cells as well as CXCR3+ Tregs derived from patients with PDAC. Our findings suggest that, in pancreatic cancer, CXCR3+ Tregs can be recruited by IP-10 expressed by PSCs in the tumor stroma, leading to immunosuppressive and tumor-promoting effects

    Elasticity curves describe streamflow sensitivity to precipitation across the entire flow distribution

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    Streamflow elasticity is a simple approximation of how responsive a river is to precipitation. It is represented as a ratio of the expected percentage change in streamflow for a 1 % change in precipitation. Typically estimated for the annual median streamflow, we here propose a new concept in which streamflow elasticity is estimated across the full range of streamflow percentiles in a large-sample context. This “elasticity curve” can be used to develop a more complete depiction of how streamflow responds to precipitation. We find three different elasticity curve types which characterize this relationship at the annual and seasonal timescales in the USA, based on two statistical modelling approaches, a panel regression which facilitates causal inference and a single catchment model which allows for consideration of static attributes. Type A describes catchments where low flows are the least and high flows are the most responsive to precipitation. The majority of catchments at the annual, winter, and fall timescales exhibit this behavior. Type B describes catchments where the response is relatively consistent across the flow distribution. At the seasonal timescale, many catchments experience a consistent level of response across the flow regime. This is especially true in snow-fed catchments during cold months, when the actual elasticity skews towards zero for all flow percentiles while precipitation is held in storage. Consistent response is also seen across the majority of the country during spring when streamflow is comparatively stable and in summer when evaporation demand is high and soil moisture is low. Finally, Type C describes catchments where low flows are the most responsive to precipitation change. These catchments are dominated by highly flashy low flow behavior. We show that the curve type varies separately from the magnitude of the elasticity. Finally, we demonstrate that available water storage is likely the key control which determines curve type
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