1,281 research outputs found

    An improved algorithm for the retrieval of ocean wave spectra from synthetic aperture radar image spectra

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    An earlier algorithm for retrieving two-dimensional wave spectra from synthetic aperture radar (SAR) image spectra is improved by using a modified cost function and introducing an additional iteration loop in which the first-guess input spectrum is systematically updated. For this purpose a spectral partitioning scheme is applied in which the spectrum is decomposed into a finite number of distinct wave systems. At each iteration step, the individual wave systems of the partitioned nth-guess wave spectrum are adjusted to agree in mean energy, frequency, and direction with the corresponding mean values of the associated wave systems of the SAR-inverted wave spectrum. The algorithm retrieves smooth wave spectra, avoiding the discontinuities which tended to arise in the previous algorithm in the transition region near the azimuthal wavenumber cutoff of the SAR image spectrum. The azimuthal cutoff of the SAR spectrum is also reproduced more accurately. The greatest improvement of the new retrieval algorithm is obtained when the discrepancies between the initial first-guess wave spectrum and the observed SAR spectrum are large. In this case the additional updating loop for the input spectrum enables the retrieved spectrum to adjust such that the simulated SAR spectrum matches more closely the observed SAR spectrum. The overall correlation of a large set of simulated SAR spectra with the measured SAR spectra is found to be significantly higher than with the previous algorithm, indicating that the algorithm not only overcomes isolated shortcomings of the earlier algorithm but also yields retrieved wave spectra which are generally more consistent with the input SAR data. An additional practical advantage of the new algorithm is that it returns spectral partioning parameters which dan be used in SAR wave data assimilation schemes

    SigWinR; the SigWin-detector updated and ported to R

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    <p>Abstract</p> <p>Background</p> <p>Our SigWin-detector discovers significantly enriched windows of (genomic) elements in any sequence of values (genes or other genomic elements in a DNA sequence) in a fast and reproducible way. However, since it is grid based, only (life) scientists with access to the grid can use this tool. Therefore and on request, we have developed the SigWinR package which makes the SigWin-detector available to a much wider audience. At the same time, we have introduced several improvements to its algorithm as well as its functionality, based on the feedback of SigWin-detector end users.</p> <p>Findings</p> <p>To allow usage of the SigWin-detector on a desktop computer, we have rewritten it as a package for R: SigWinR. R is a free and widely used multi platform software environment for statistical computing and graphics. The package can be installed and used on all platforms for which R is available. The improvements involve: a visualization of the input-sequence values supporting the interpretation of Ridgeograms; a visualization allowing for an easy interpretation of enriched or depleted regions in the sequence using windows of pre-defined size; an option that allows the analysis of circular sequences, which results in rectangular Ridgeograms; an application to identify regions of co-altered gene expression (ROCAGEs) with a real-life biological use-case; adaptation of the algorithm to allow analysis of non-regularly sampled data using a constant window size in physical space without resampling the data. To achieve this, support for analysis of windows with an even number of elements was added.</p> <p>Conclusion</p> <p>By porting the SigWin-detector as an R package, SigWinR, improving its algorithm and functionality combined with adequate performance, we have made SigWin-detector more useful as well as more easily accessible to scientists without a grid infrastructure.</p

    Structure of Aspergillus fumigatus Cytosolic thiolase: trapped tetrahedral reaction intermediates and activation by monovalent cations

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    Cytosolic thiolase (CT) catalyzes the reversible Claisen condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA. The reaction cycle proceeds via a ping-pong mechanism involving an acetylated enzyme intermediate and two separate oxyanion holes which stabilize negatively charged reaction intermediates. This is the initial step in the synthesis of ergosterol in the prominent fungal pathogen Aspergillus fumigatus and is essential for the growth and survival of the organism. Here, we present crystal structures of A. fumigatus CT in liganded and apo forms and in a complex with different monovalent cations. Careful observation of the electron density at the active sites of two different afCT structures crystallized in the presence of acetyl-CoA shows that our crystals have trapped various stages of the thiolase catalytic cycle, including two tetrahedral reaction intermediates that have previously eluded structural characterization. Unexpectedly, we have also shown that afCT is activated by monovalent cations, a biochemical property previously thought to apply only to the mitochondrial biosynthetic thiolase, with a preference for potassium ions. Structures of fungal CT provide valuable insight into the thiolase reaction cycle and allosteric activation of members of this class of enzymes by monovalent cations.Andrew C. Marshall, Charles S. Bond, and John B. Brunin

    Descriptive Epidemiology of Bovine Tuberculosis in Michigan (1975–2010): Lessons Learned

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    Despite ongoing eradication efforts, bovine tuberculosis (BTB) remains a challenge in Michigan livestock and wildlife. The objectives of this study were to (1) review the epidemiology of BTB in Michigan cattle, privately owned cervids, and wildlife between 1975 and 2010 and (2) identify important lessons learned from the review and eradication strategies. BTB information was accessed from the Michigan BTB Eradication Project agencies. Cattle herds (49), privately owned deer herds (4), and wild white-tailed deer (668) were found infected with BTB during the review period. BTB has occurred primarily in counties located at the northern portion of the state's Lower Peninsula. Currently used BTB eradication strategies have successfully controlled BTB spread. However additional changes in BTB surveillance, prevention, and eradication strategies could improve eradication efforts

    Проблемы технического нормирования шумовых характеристик текстильных машин

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    Для целей оценки соответствия шумовых характеристик машин требованиям санитарных норм предложено использовать обобщенные предельно допустимые шумовые характеристики, которые задают предельно допустимые характеристики для близких по типу машин, объединенных в группы с учетом характерной плотности их установки и условий эксплуатации. Для уточненного определения этих характеристик целесообразно использовать методику, учитывающую звукопоглощение и рассеяние шума поверхностью машин, плотность тел рассеяния в поперечном сечении производственного помещения и его акустические и геометрические характеристики.For the purposes of assessing the compliance of noise characteristics of machines with the requirements of sanitary standards, it is suggested to use generalized maximum permissible noise characteristics that set the maximum permissible characteristics for similar machines, grouped together, taking into account the characteristic density of their installation and operating conditions. For an accurate definition of these characteristics, it is advisable to use a technique that takes into account the sound absorption and noise scattering by the machine surface, the density of scattering bodies in the cross section of the production room and its acoustic and geometric characteristics

    Characteristics of Lightning Within Electrified Snowfall Events Using Lightning Mapping Arrays

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    This study examined 34 lightning flashes within four separate thundersnow events derived from lightning mapping arrays (LMAs) in northern Alabama, central Oklahoma, and Washington, DC. The goals were to characterize the in-cloud component of each lightning flash, as well as the correspondence between the LMA observations and lightning data taken from national lightning networks like the National Lightning Detection Network (NLDN). Individual flashes were examined in detail to highlight several observations within the dataset. The study results demonstrated that the structures of these flashes were primarily normal polarity. The mean area encompassed by this set of flashes is 375 square kilometers, with a maximum flash extent of 2300 square kilometers, a minimum of 3 square kilometers, and a median of 128 square kilometers. An average of 2.29 NLDN flashes were recorded per LMA-derived lightning flash. A maximum of 11 NLDN flashes were recorded in association with a single LMA-derived flash on 10 January 2011. Additionally, seven of the 34 flashes in the study contain zero NLDN identified flashes. Eleven of the 34 flashes initiated from tall human-made objects (e.g., communication towers). In at least six lightning flashes, the NLDN detected a return stroke from the cloud back to the tower and not the initial upward leader. This study also discusses lightning's interaction with the human built environment and provides an example of lightning within heavy snowfall observed by GOES-16's Geostationary Lightning Mapper

    The 13 years of TRMM Lightning Imaging Sensor: From Individual Flash Characteristics to Decadal Tendencies

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    How often lightning strikes the Earth has been the object of interest and research for decades. Several authors estimated different global flash rates using ground-based instruments, but it has been the satellite era that enabled us to monitor lightning thunderstorm activity on the time and place that lightning exactly occurs. Launched into space as a component of NASA s Tropical Rainfall Measuring Mission (TRMM) satellite, in November 1997, the Lighting Imaging Sensor (LIS) is still operating. LIS detects total lightning (i.e., intracloud and cloud-to-ground) from space in a low-earth orbit (35deg orbit). LIS has collected lightning measurements for 13 years (1998-2010) and here we present a fully revised and current total lightning climatology over the tropics. Our analysis includes the individual flash characteristics (number of events and groups, total radiance, area footprint, etc.), composite climatological maps, and trends for the observed total lightning during these 13 years. We have identified differences in the energetics of the flashes and/or the optical scattering properties of the storms cells due to cell-relative variations in microphysics and kinematics (i.e., convective or stratiform rainfall). On the climatological total lightning maps we found a dependency on the scale of analysis (resolution) in identifying the lightning maximums in the tropics. The analysis of total lightning trends observed by LIS from 1998 to 2010 in different temporal (annual and seasonal) and spatial (large and regional) scales, showed no systematic trends in the median to lower-end of the distributions, but most places in the tropics presented a decrease in the highest total lightning flash rates (higher-end of the distributions)

    Evidence of sound production by spawning lake trout (Salvelinus namaycush) in lakes Huron and Champlain

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    Two sounds associated with spawning lake trout (Salvelinus namaycush) in lakes Huron and Champlain were characterized by comparing sound recordings with behavioral data collected using acoustic telemetry and video. These sounds were named “growls” and “snaps” and were heard on lake trout spawning reefs, but not on a nonspawning reef, and were more common at night than during the day. Growls also occurred more often during the spawning period than the prespawning period, while the trend for snaps was reversed. In a laboratory flume, sounds occurred when male lake trout were displaying spawning behaviors: growls when males were quivering and parallel swimming and snaps when males moved their jaw. Combining our results with the observation of possible sound production by spawning splake (Salvelinus fontinalis × Salvelinus namaycush hybrid) provides rare evidence for spawning-related sound production by a salmonid or any other fish in the superorder Protacanthopterygii. Further characterization of these sounds could be useful for lake trout assessment, restoration, and control

    Quantum Fields in Hyperbolic Space-Times with Finite Spatial Volume

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    The one-loop effective action for a massive self-interacting scalar field is investigated in 44-dimensional ultrastatic space-time R×H3/Γ R \times H^3/\Gamma, H3/ΓH^3/\Gamma being a non-compact hyperbolic manifold with finite volume. Making use of the Selberg trace formula, the ζ\zeta-function related to the small disturbance operator is constructed. For an arbitrary gravitational coupling, it is found that ζ(s)\zeta(s) has a simple pole at s=0s=0. The one-loop effective action is analysed by means of proper-time regularisations and the one-loop divergences are explicitly found. It is pointed out that, in this special case, also ζ\zeta-function regularisation requires a divergent counterterm, which however is not necessary in the free massless conformal invariant coupling case. Finite temperature effects are studied and the high-temperature expansion is presented. A possible application to the problem of the divergences of the entanglement entropy for a free massless scalar field in a Rindler-like space-time is briefly discussed.Comment: 13 pages, LaTex. The contribution of hyperbolic elements has been added. Other minor corrections and reference
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