1,539 research outputs found
Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review
The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed. In this paper the role of the hypothalamus-pituitary-thyroid axis (HPT-axis) and the hypothalamus-pituitary-adrenal axis (HPA-axis) in the ontogeny of avian thermoregulation is evaluated. The regulatory mechanisms and different important hormones of both axes, which have stimulatory or inhibitory effects, are discussed. Because the onset of functionality of the thermoregulatory system is of great interest, the ontogeny and functionality of the hormonal axes are clarified. There is a great difference between precocial and altricial birds in hormonal events as well as in neural processes which are involved in the emergence of thermoregulation. In precocial avian species the HPT-axis becomes functional during the mid- to late embryonic period while the same axis only becomes fully functional during the first week post-hatch in altricial avian species. As early as the sixties, the emergence of homeothermy in chickens was investigated. It was concluded that the thyroid gland plays an important role in the thermoregulatory mechanisms of newly hatched chicks. More recent studies however were not able to show any direct effect of the thyroid hormones on the thermoregulation of day-old chicks, although blocking the conversion of T4 to T3 caused a decrease in body temperature in young chicks. Thyrotropin releasing hormone (TRH) is known to act in thermoregulation in mammals and several authors have found an effect of TRH on the metabolism of young and older chicks. However, the exact mechanism still remains unclear. Because the HPT- and the HPA-axis show close relationships, the role of the HPA-axis in the ontogeny of thermoregulation is also taken into consideration in this review. In mammals as well as in birds, corticotropin releasing hormone (CRH) is involved in the primary thermoregulation. We conclude that the HPT-axis has an important role in the ontogeny of avian thermoregulation. The exact role of the HPA-axis remains largely unclear although at least CRH is definitely of some importance
Factors Influencing Pika Foraging Behavior in the North Cascades National Park Service Complex, Washington
The American pika (Ochotona princeps) is a small lagomorph restricted to talus slopes at higher elevations or latitudes throughout mountainous regions in western North America. Pikas respond to seasonal fluctuations in food availability by haying, i.e., storing, vegetation for use during winter, and are considered a climate change indicator species because of their sensitivity to heat and restricted habitat requirements. Prior to 2009, no data existed on pika populations or foraging behavior in the North Cascades National Park Service Complex (NOCA) in Washington. To help address these data needs, we collected behavioral data on 95 foraging pikas throughout NOCA during summer 2009 and 2010 to better understand abiotic and biotic factors affecting foraging behavior and potential impacts of climate change on pikas. We calculated the proportion of time pikas spent grazing and haying, and developed competing hypotheses for each behavior expressed as logistic regression models consisting of climate, vegetation, elevation, date, and year covariates. We selected top models for both behaviors using information-theoretic techniques, and found that time spent grazing decreased while haying behavior increased through summer. Pikas spent more time haying as elevation increased while time spent grazing was negatively correlated with elevation, suggesting possible constraints in time available for foraging at higher elevations. Time spent grazing was also negatively correlated with temperature, a result likely in response to thermoregulation limitations of pikas. These results demonstrate how multiple factors may affect pika foraging behavior, thereby providing an opportunity to assist resource managers in future decisions regarding pika conservation
Signatures of superconducting gap inhomogeneities in optical properties
Scanning tunneling spectroscopy applied to the high- cuprates has
revealed significant spatial inhomogeneity on the nanoscale. Regions on the
order of a coherence length in size show variations of the magnitude of the
superconducting gap of order or more. An important unresolved question
is whether or not these variations are also present in the bulk, and how they
influence superconducting properties. As many theories and data analyses for
high- superconductivity assume spatial homogeneity of the gap magnitude,
this is a pressing question. We consider the far-infrared optical conductivity
and evaluate, within an effective medium approximation, what signatures of
spatial variations in gap magnitude are present in various optical quantities.
In addition to the case of d-wave superconductivity, relevant to the high-
cuprates, we have also considered s-wave gap symmetry in order to provide
expected signatures of inhomogeneities for superconductors in general. While
signatures of gap inhomogeneities can be strongly manifested in s-wave
superconductors, we find that the far-infrared optical conductivity in d-wave
is robust against such inhomogeneity.Comment: 8 pages, 7 figure
Self consistent determination of plasmonic resonances in ternary nanocomposites
We have developed a self consistent technique to predict the behavior of
plasmon resonances in multi-component systems as a function of wavelength. This
approach, based on the tight lower bounds of the Bergman-Milton formulation, is
able to predict experimental optical data, including the positions, shifts and
shapes of plasmonic peaks in ternary nanocomposites without using any ftting
parameters. Our approach is based on viewing the mixing of 3 components as the
mixing of 2 binary mixtures, each in the same host. We obtained excellent
predictions of the experimental optical behavior for mixtures of Ag:Cu:SiO2 and
alloys of Au-Cu:SiO2 and Ag-Au:H2 O, suggesting that the essential physics of
plasmonic behavior is captured by this approach.Comment: 7 pages and 4 figure
The effects of elimination and non-elimination games on physical activity and psychosocial responses in children
Master of ScienceDepartment of KinesiologyDavid A. DzewaltowskiPhysically active games are one way to increase caloric expenditure in children. It is unknown if the structure of physically active games impacts physical activity levels. Furthermore, there has been no research examining psychosocial responses during a single game session. This study examined the effects of elimination games (EG) and non-elimination games (NEG) on physical activity (PA), self-efficacy (SE), peer victimization (PV), and enjoyment in children.
Children (n=29) in 4th-6th grade (65.5% male) participated in two sessions where they played either NEG or EG. Children were stratified according to gender and weight status into game sessions that were counter-balanced across two days. Each session consisted of playing two games 20 min. in duration. NEG were adopted from the evidence-based Coordinated Approach to Child Health (CATCH) games curriculum and modified for EG. Each child wore an Actigraph GT1M accelerometer and completed an 11-item questionnaire measuring self-efficacy, peer victimization, and enjoyment before and after each game session. Accelerometer data was analyzed using resting energy expenditure (METs).
A mixed effects regression model was conducted with child and day nested within child as random effects and observation, game session, weight status, and gender as fixed effects. Overall, girls spent more time in sedentary PA compared to boys (p=0.0123). Children engaged in significantly more moderate-vigorous PA during NEG compared to EG (p=0.0013), ostensibly because of more time in moderate PA during NEG (p=0.0002) and less time in sedentary PA (p<0.0001). Furthermore, children significantly increased SE after playing both game sessions (p=0.0349), but a significant interaction between game session and time of measurement in the prediction of enjoyment showed that enjoyment increased after EG and decreased after NEG (p=0.0138). There were no differences in PV or weight status.
These results provide preliminary evidence that NEG provide a greater amount of moderate-vigorous PA compared to EG and introduces differences in enjoyment responses during EG and NEG. Therefore, it is important to promote NEG to increase physical activity, but also important to monitor enjoyment responses to promote a healthy, but fun environment for children
Nuclear data uncertainty quantification on PWR spent nuclear fuel as a function of burnup
Nuclear data uncertainty analysis on the spent nuclear fuel inventory was performed on the Takahama-3 NT3G23 assembly, where the sample SF95-4 was irradiated up to a burnup of approximately 36 GWd/ t according to the SFCOMPO benchmark. The cross-section covariance matrices stored in the ENDF/B-VIII.0, JEFF-3.3 and JENDL-4.0u evaluated nuclear data libraries were propagated with the stochastic sampling algorithms implemented in the SANDY code. A comparison of the concentration uncertainty differences obtained using data from the three libraries is reported. Similarities were found with the fuel composition uncertainty results obtained for the Calvert Cliffs MKP109 sample P SFCOMPO benchmark. Such a similarity was also found when comparing concentration uncertainties along the sample irradiation. Therefore, the main contributors to the concentration uncertainty of a number of nuclides were identified at different burnup levels in the two samples. To complement the similarity analysis, a correlation study of the concentration distributions predicted by the two models was performed. The reported results hint a dominance of the common uncertainty propagation mechanisms over the model differences in the determination of concentration uncertainty
Stem Cells and Cancer The Polycomb Connection
AbstractProteins from the Polycomb group (PcG) are epigenetic chromatin modifiers involved in cancer development and also in the maintenance of embryonic and adult stem cells. The therapeutic potential of stem cells and the growing conviction that tumors contain stem cells highlights the importance of understanding the extrinsic and intrinsic circuitry controlling stem cell fate and their connections to cancer
Plasmon tunability in metallodielectric metamaterials
The dielectric properties of metamaterials consisting of periodically
arranged metallic nanoparticles of spherical shape are calculated by rigorously
solving Maxwell's equations. Effective dielectric functions are obtained by
comparing the reflectivity of planar surfaces limiting these materials with
Fresnel's formulas for equivalent homogeneous media, showing mixing and
splitting of individual-particle modes due to inter-particle interaction.
Detailed results for simple cubic and fcc crystals of aluminum spheres in
vacuum, silver spheres in vacuum, and silver spheres in a silicon matrix are
presented. The filling fraction of the metal f is shown to determine the
position of the plasmon modes of these metamaterials. Significant deviations
are observed with respect to Maxwell-Garnett effective medium theory for large
f, and multiple plasmons are predicted to exist in contrast to Maxwell-Garnett
theory.Comment: 6 pages, 4 figure
Maize, Switchgrass, and Ponderosa Pine Biochar Added to Soil Increased Herbicide Sorption and Decreased Herbicide Efficacy
Biochar, a by-product of pyrolysis made from a wide array of plant biomass when producing biofuels, is a proposed soil amendment to improve soil health. This study measured herbicide sorption and efficacy when soils were treated with low (1% w/w) or high (10% w/w) amounts of biochar manufactured from different feedstocks [maize (Zea mays) stover, switchgrass (Panicum vigatum), and ponderosa pine (Pinus ponderosa)], and treated with different post-processing techniques. Twenty-four hour batch equilibration measured sorption of 14C-labelled atrazine or 2,4-D to two soil types with and without biochar amendments. Herbicide efficacy was measured with and without biochar using speed of seed germination tests of sensitive species. Biochar amended soils sorbed more herbicide than untreated soils, with major differences due to biochar application rate but minor differences due to biochar type or post-process handling technique. Biochar presence increased the speed of seed germination compared with herbicide alone addition. These data indicate that biochar addition to soil can increase herbicide sorption and reduce efficacy. Evaluation for site-specific biochar applications may be warranted to obtain maximal benefits without compromising other agronomic practices
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