Last Night On The Back Porch : I Loved Her Best Of All

https://digitalcommons.library.umaine.edu/mmb-vp/1953/thumbnail.jp

Toll-like Receptor 2 and 4 (TLR2 and TLR4) Agonists Differentially Regulate Secretory Interleukin-1 Receptor Antagonist Gene Expression in Macrophages

Treatment of macrophages with lipopolysaccharide (LPS) from Gram-negative bacteria or peptidoglycan (PGN) from Gram-positive bacteria activates multiple intracellular signaling pathways and a large, diverse group of nuclear transcription factors. The signaling receptors for PGN and LPS are now known to be the Toll-like receptors 2 and 4 (TLR2 and -4, respectively). While a large body of literature indicates that the members of the TLR family activate nearly identical cytoplasmic signaling programs, several recent reports have suggested that the functional outcomes of signaling via TLR2 or TLR4 are not equivalent. In the current studies, we compared the responses of the secretory IL-1 receptor antagonist (sIL-1Ra) gene to both LPS and PGN. Both LPS and PGN induced IL-1Ra gene expression; however, the combination of both stimuli synergistically increased sIL-1Ra mRNA expression and promoter activity, suggesting that the signals induced by PGN and LPS are not equivalent. While both LPS and PGN utilized the PU.1-binding sites in the proximal sIL-1Ra promoter region to generate a full response, additional distinct promoter elements were utilized by LPS or PGN. Activation of p38 stress-activated protein kinase was required for LPS- or PGN-induced IL-1Ra gene expression, but the p38-responsive promoter elements localized to distinct regions of the sIL-1Ra gene. Additionally, while the LPS-induced, p38-dependent response was dependent upon PU.1 binding, the PGN-induced, p38 response was not. Collectively, these data indicated that while some of the intracellular signaling events by TLR2 and TLR4 agonists are similar, there are clearly distinct differences in the responses elicited by these two bacterial products

Dielectrowetting Driven Spreading of Droplets

The wetting of solid surfaces can be modified by altering the surface free energy balance between the solid, liquid, and vapor phases. Here we show that liquid dielectrophoresis induced by nonuniform electric fields can be used to enhance and control the wetting of dielectric liquids. In the limit of thick droplets, we show theoretically that the cosine of the contact angle follows a simple voltage squared relationship analogous to that found for electrowetting on dielectric. Experimental observations confirm this predicted dielectrowetting behavior and show that the induced wetting is reversible. Our findings provide a noncontact electrical actuation process for meniscus and droplet control

Instructor-Student Classroom Interactions: An Experimental Study of Language, Sex-Differences, and Student Perceptions of Instructors

Higher education instructors must establish meaningful relationships with students in order to be effective. Student ratings of instructor dynamism, approachability, and credibility impact overall evaluations of instructors. Instructor use of strategic language choices, such as slang use in the classroom, impact these student evaluations. Here, the outcome of language choices’ impact on student evaluations is explored. To do so, both instructor and student sex main effects and interactions are tested. Last, specific methods, findings, as well as meaning and application are covered. Overall, instructor use of slang impacts student evaluations

Carl R. Brown to Dear Mr. Meredith (Undated)

https://egrove.olemiss.edu/mercorr_pro/1762/thumbnail.jp

Improving the Way to the Land of Opportunity: Internal Improvements in Antebellum Arkansas

This dissertation investigates the importance of transportation in the development of Arkansas from its pre-colonial days to the Civil War. The study asks why Arkansas differed from other southern states in its position on internal improvements. Focused more on the old frontier east of the Mississippi River, studies of internal improvements have skimmed over developments west of the river until the railroad era of the 1850s and later. These studies highlighted the debate over the constitutionality of federally-funded internal improvements, indicating that most southerners were against federal involvement, while most northerners and westerners advocated federal aid. This study finds that due to its remote location between the two colonial population centers of St. Louis to the north and New Orleans to the south, early Arkansas lagged behind its neighbors in growth, relying on the natural watercourses that flowed through the region, resulting in riparian settlement. When Arkansas became a territory and drew ambitious men to the frontier, they demanded better communications to the East, frontier defense against Indian raids, and all-year transportation within the territory. Without improved rivers and roads, settlers could not move into Arkansas and purchase public lands which limited the tax base for making the needed improvements. Subsequently, to pay for and make these improvements Arkansas, unlike other slave states, relied on federal appropriations and the military during its territorial period. After gaining statehood in 1836, federal land donations replaced federal appropriations to pay for improvements. Seeking to be an integral part of a transcontinental route, the use of corporations failed to generate sufficient capital to successfully build railroads across Arkansas.By 1861, none of the major improvements in Arkansas was finished. Through mainly primary sources, this dissertation concludes that early federal policies suppressed improvements in Arkansas until the 1820s and that most Arkansans desired federally-funded improvements regardless of sectional and political party affiliations, debating instead on their optimal locations. Travel conditions warranting improvements and the benefits those improvements offered are evidenced through primary accounts and documents, giving a more complete picture of why Arkansas countered most slave states by seeking federal assistance

Last Night On The Back Porch (I Loved Her Best Of All)

[Verse 1]There’s a girl I’m wild aboutEv’ry time I take her out I hug herI squeeze herI tease her soAnd we always can be foundWhere there’s no one else aroundDo we cuddle?Do we pet? You ain’t heard nothin’ yet. [Verse 2]Ev’rytime she’s aloneWhen i call her on the phoneI hurryI scurryI worry soI’m afraid that I might see Someone there in place of me If I lost her What blow I love her Oh! Oh! Oh! [Chorus]I love her in the morning And I love her at nightI love her, yes I love her When the stars are shinning brightI love her in the springtime and I love her in the fall,But last night on the back porch I loved her best of all. I all The first time that I met her It was true love at first sight in the parlor taxi