6,246 research outputs found
Comparative review of the effects of organic farming on biodiversity (OF0149)
This is the final report of Defra project OF0149
1. The report reviews the impact of different farming regimes and makes a comparative study of their influence on the biodiversity of arable farmland.
2. Within this review, the evaluation of impacts on biodiversity focuses on species and habitats, and includes both the number, abundance and activity of species (section 1.3).
3. Five farming regimes are defined and discussed, namely Conventional Arable, Conventional Mixed Lowland, Organic and two integrated production regimes - LEAF (Linking Environment and Farming) and IFS-Experimental regimes The main differences between the regimes in relation to the use of external inputs and other agricultural practices are discussed. The review draws on both UK and European information (section 1.4).
4. The effect of each farming regime on biodiversity is assessed according to the agricultural practices adopted and to the occurrence and management of uncropped land present. Agricultural practices are reviewed within the following categories: cultivation, crop production, crop protection and post-cropping practice (section 2.1).
5. Among the agricultural practices examined, those associated with crop protection and the artificial inputs associated with crop production were seen as the most adverse for biodiversity. Several practices were seen to benefit the biodiversity of arable land. These included set-aside, crop rotations with grass leys, spring sowing, permanent pasture, green manuring and intercropping (section 2.7).
6. Uncropped areas, such as sown grass strips (beetle banks), grass margins and conservation headlands, were seen as critical for the maintenance of biodiversity on arable farmland. Changes in the balance of cropped to uncropped land within some farming regimes, linked to increase in field size, have had a major impact on the diversity of flora and fauna associated with those regimes (section 3.4).
7. Based on the evaluation of agricultural practices used, the occurrence of uncropped land and the extent of the farming regime within England and Wales, it was concluded that Conventional Arable regimes act effectively to maintain the impoverished status of biodiversity on arable land. Extreme examples can be found of intensively managed farms that further deplete biodiversity and sympathetically managed farms that try to enhance it. Increased adoption of agricultural practices such as direct drilling, use of farmyard manure, set-aside, use of crop rotations with leys, or an increase in the incidence and sympathetic management of uncropped areas may well assist biodiversity on farms within this regime (sections 4.3 & 4.4)
8. Organic regimes were shown to have an overall benefit for biodiversity at the farm level, both in terms of the agricultural practices adopted and in the occurrence and management of uncropped areas (sections 4.3 & 4.4).
9. Conventional Mixed Lowland and LEAF regimes were both seen to have the potential for enhancing biodiversity on arable land. Here, adverse impacts associated with crop protection and crop production may be mitigated by beneficial effects associated with post-cropping practices, the occurrence of permanent pasture and uncropped land. At present, the extent to which enhancement may be achieved, may well depend on the extent, condition and management of uncropped land present within these regimes (sections 4.3 & 4.4).
10. IFS-experimental regimes were seen to have a beneficial effect on biodiversity, due to the stringent procedures used for targeting herbicides and pesticides and for establishing and managing uncropped areas. At present these regimes occupy a tiny area of the national resource of arable land and thus their impact on national biodiversity is likely to be insignificant at the present time (sections 4.3 & 4.4).
11. A number of areas are highlighted for further consideration. These include:
• monitoring of biodiversity on farms pre- and post- conversion to organic farming,
• comparative studies that focus on the effectiveness of different regimes or agricultural practices in enhancing biodiversity on species-impoverished intensively managed arable land,
• manipulative experiments to determine the optimal balance of cropped to uncropped areas for enhancing biodiversity,
• manipulative experiments to examine the separate impacts of rotational regimes and agricultural inputs on biodiversity,
• an economic assessment of the costs and benefits in both production and biodiversity terms, of conversion to organic, integrated production or uptake of available agri-environment schemes
Should Your Wearables Be Shareable? The Ethics of Wearable Technology in Collegiate Athletics
Lower Extremity Passive Range of Motion in Community-Ambulating Stroke Survivors
Background: Physical therapists may prescribe stretching exercises for individuals with stroke to improve joint integrity and to reduce the risk of secondary musculoskeletal impairment. While deficits in passive range of motion (PROM) exist in stroke survivors with severe hemiparesis and spasticity, the extent to which impaired lower extremity PROM occurs in community-ambulating stroke survivors remains unclear. This study compared lower extremity PROM in able-bodied individuals and independent community-ambulatory stroke survivors with residual stroke-related neuromuscular impairments. Our hypothesis was that the stroke group would show decreased lower extremity PROM in the paretic but not the nonparetic side and that decreased PROM would be associated with increased muscle stiffness and decreased muscle length. Methods: Individuals with chronic poststroke hemiparesis who reported the ability to ambulate independently in the community (n = 17) and age-matched control subjects (n = 15) participated. PROM during slow (5 degrees/sec) hip extension, hip flexion, and ankle dorsiflexion was examined bilaterally using a dynamometer that measured joint position and torque. The maximum angular position of the joint (ANGmax), torque required to achieve ANGmax (Tmax), and mean joint stiffness (K) were measured. Comparisons were made between able-bodied and paretic and able-bodied and nonparetic limbs. Results: Contrary to our expectations, between-group differences in ANGmax were observed only during hip extension in which ANGmax was greater bilaterally in people post-stroke compared to control subjects (P ≤ 0.05; stroke = 13 degrees, able-bodied = −1 degree). Tmax, but not K, was also significantly higher during passive hip extension in paretic and nonparetic limbs compared to control limbs (P ≤ 0.05; stroke = 40 Nm, able-bodied = 29 Nm). Compared to the control group, Tmax was increased during hip flexion in the paretic and nonparetic limbs of post-stroke subjects (P ≤ 0.05, stroke = 25 Nm, able-bodied = 18 Nm). K in the nonparetic leg was also increased during hip flexion (P ≤ 0.05, nonparetic = 0.52 Nm/degree, able-bodied = 0.37 Nm/degree.) Conclusion: This study demonstrates that community-ambulating stroke survivors with residual neuromuscular impairments do not have decreased lower extremity PROM caused by increased muscle stiffness or decreased muscle length. In fact, the population of stroke survivors examined here appears to have more hip extension PROM than age-matched able-bodied individuals. The clinical implications of these data are important and suggest that lower extremity PROM may not interfere with mobility in community-ambulating stroke survivors. Hence, physical therapists may choose to recommend activities other than stretching exercises for stroke survivors who are or will become independent community ambulators
Major health-related behaviours and mental well-being in the general population : the health survey for England
Background: Major behavioural risk factors are known to adversely affect health outcomes and be strongly associated with mental illness. However, little is known about the association of these risk factors with mental well-being in the general population. We sought to examine behavioural correlates of high and low mental well-being in the Health Survey for England.
Methods: Participants were 13 983 adults, aged 16 years and older (56% females), with valid responses for the combined 2010 and 2011 surveys. Mental well-being was assessed using the Warwick-Edinburgh Mental Well-being Scale (WEMWBS). ORs of low and high mental well-being, compared to the middle-range category, were estimated for body mass index (BMI), smoking, drinking habits, and fruit and vegetable intake.
Results: ORs for low mental well-being were increased in obese individuals (up to 1.72, 95% CI 1.26 to 2.36 in BMI 40+ kg/m2). They increased in a linear fashion with increasing smoking (up to 1.98, 95% CI 1.55 to 2.53, >20 cigarettes/day) and with decreasing fruit and vegetable intake (up to 1.53, 95% CI 1.24 to 1.90, <1 portion/day); whereas ORs were reduced for sensible alcohol intake (0.78, 95% CI 0.66 to 0.91, ≤4 units/day in men, ≤3 units/day in women). ORs for high mental well-being were not correlated with categories of BMI or alcohol intake. ORs were reduced among ex-smokers (0.81, 95% CI 0.71 to 0.92), as well as with lower fruit and vegetable intake (up to 0.79, 95% CI 0.68 to 0.92, 1 to <3 portions/day).
Conclusions; Along with smoking, fruit and vegetable consumption was the health-related behaviour most consistently associated with mental well-being in both sexes. Alcohol intake and obesity were associated with low, but not high mental well-being
Single-cell analysis of [Ca<sup>2+</sup>]i signalling in sub-fertile men:characteristics and relation to fertilization outcome
STUDY QUESTIONWhat are the characteristics of progesterone-induced (CatSper-mediated) single cell [Ca2+]i signals in spermatozoa from sub-fertile men and how do they relate to fertilizing ability?SUMMARY ANSWERSingle cell analysis of progesterone-induced (CatSper-mediated) [Ca2+]i showed that reduced progesterone-sensitivity is a common feature of sperm from sub-fertile patients and is correlated with fertilization rate.WHAT IS KNOWN ALREADYStimulation with progesterone is a widely used method for assessing [Ca2+]i mobilization by activation of CatSper in human spermatozoa. Although data are limited, sperm population studies have indicated an association of poor [Ca2+]i response to progesterone with reduced fertilization ability.STUDY DESIGN, SIZE, DURATIONThis was a cohort study using semen samples from 21 donors and 101 patients attending the assisted conception unit at Ninewells Hospital Dundee who were undergoing ART treatment. Patients were recruited from January 2016 to June 2017.PARTICIPANTS/MATERIALS, SETTING, METHODSSemen donors and patients were recruited in accordance with local ethics approval (13/ES/0091) from the East of Scotland Research Ethics Service (EoSRES) REC1. [Ca2+]i responses were examined by single cell imaging and motility parameters assessed by computer-assisted sperm analysis (CASA).MAIN RESULTS AND THE ROLE OF CHANCEFor analysis, patient samples were divided into three groups IVF(+ve) (successful fertilization; 62 samples), IVF-FF (failed fertilization; eight samples) and ICSI (21 samples). A further 10 IVF samples showed large, spontaneous [Ca2+]i oscillations and responses to progesterone could not be analysed. All patient samples loaded with the [Ca2+]i-indicator fluo4 responded to progesterone stimulation with a biphasic increase in fluorescence (transient followed by plateau) which resembled that seen in progesterone-stimulated donor samples. The mean normalized response (progesterone-induced increase in fluorescence normalized to resting level) was significantly smaller in IVF-FF and ICSI patient groups than in donors. All samples were further analysed by plotting, for each cell, the relationship between resting fluorescence intensity and the progesterone-induced fluorescence increment. In donor samples these plots overlaid closely and had a gradient of ≈ 2 and plots for most IVF(+ve) samples closely resembled the donor distribution. However, in a subset (≈ 10%) of IVF(+ve) samples, 3/8 IVF-FF samples and one-third of ICSI samples the gradient of the plot was significantly lower, indicating that the response to progesterone of the cells in these samples was abnormally small. Examination of the relationship between gradient (regression coefficient of the plot) in IVF samples and fertilization rate showed a positive correlation. In IVF-FF and ICSI groups, the proportion of cells in which a response to progesterone could be detected was significantly lower than in donors and IVF (+ve) patients. Approximately 20% of cells in donor, IVF(+ve) and ICSI samples generated [Ca2+]i oscillations when challenged with progesterone but in IVF-FF samples only ≈ 10% of cells generated oscillations and there was a significantly greater proportion of samples where no oscillations were observed. Levels of hyperactivated motility were lower in IVF(+ve) and IVF-FF groups compared to controls, IVF-FF also having lower levels than IVF(+ve).LIMITATIONS, REASONS FOR CAUTIONThis is an in vitro study and caution must be taken when extrapolating these results in vivo.WIDER IMPLICATIONS OF THE FINDINGSThis study reveals important details of impaired [Ca2+]i signalling in sperm from sub-fertile men that cannot be detected in population studies
Action-Packed Action Research: How Comic Books, Questions, and Reflection Can Transform Information Literacy Instruction
How many questions can you generate when looking at a single comic panel? Which are researchable, and why? These are questions that we’ve asked our students and our library colleagues. We invite you to ask these questions and more, and consider the broader significance of question-asking and reflective teaching to information literacy and ask if there is a place for comics -- or image-laden materials -- in your classroom
Exploring the role of pain as an early predictor of category 2 pressure ulcers: a prospective cohort study
Objective To explore pressure area related pain as a predictor of category ≥2 pressure ulcer (PU) development.
Design Multicentre prospective cohort study.
Setting UK hospital and community settings.
Participants inclusion Consenting acutely ill patients aged ≥18 years, defined as high risk (Braden bedfast/chairfast AND completely immobile/very limited mobility; pressure area related pain or; category 1 PU).
Exclusion Patients too unwell, unable to report pain, 2 or more category ≥2 PUs.
Follow-up Twice weekly for 30 days.
Primary and secondary outcome measures Development and time to development of one or more category ≥2 PUs.
Results Of 3819 screened, 1266 were eligible, 634 patients were recruited, 32 lost to follow-up, providing a 602 analysis population. 152 (25.2%) developed one or more category ≥2 PUs. 464 (77.1%) patients reported pressure area related pain on a healthy, altered or category 1 skin site of whom 130 (28.0%) developed a category ≥2 PU compared with 22 (15.9%) of those without pain. Full stepwise variable selection was used throughout the analyses. (1) Multivariable logistic regression model to assess 9 a priori factors: presence of category 1 PU (OR=3.25, 95% CI (2.17 to 4.86), p<0.0001), alterations to intact skin (OR=1.98, 95% CI (1.30 to 3.00), p=0.0014), pressure area related pain (OR=1.56, 95% CI (0.93 to 2.63), p=0.0931). (2) Multivariable logistic regression model to account for overdispersion: presence of category 1 PU (OR=3.20, 95% CI (2.11 to 4.85), p<0.0001), alterations to intact skin (OR=1.90, 95% CI (1.24 to 2.91), p=0.0032), pressure area related pain (OR=1.85, 95% CI (1.07 to 3.20), p=0.0271), pre-existing category 2 PU (OR=2.09, 95% CI (1.35 to 3.23), p=0.0009), presence of chronic wound (OR=1.66, 95% CI (1.06 to 2.62), p=0.0277), Braden activity (p=0.0476). (3) Accelerated failure time model: presence of category 1 PU (AF=2.32, 95% CI (1.73 to 3.12), p<0.0001), pressure area related pain (AF=2.28, 95% CI (1.59 to 3.27), p<0.0001). (4) 2-level random-intercept logistic regression model: skin status which comprised 2 levels (versus healthy skin); alterations to intact skin (OR=4.65, 95% CI (3.01 to 7.18), p<0.0001), presence of category 1 PU (OR=17.30, 95% CI (11.09 to 27.00), p<0.0001) and pressure area related pain (OR=2.25, 95% CI (1.53 to 3.29), p<0.0001).
Conclusions This is the first study to assess pain as a predictor of category ≥2 PU development. In all 4 models, pain emerged as a risk factor associated with an increased probability of category ≥2 PU development
RP-1 and JP-8 Thermal Stability Experiments
This work experimentally investigates the effect of fuel composition changes on jet and rocket fuel thermal stability. A High Reynolds Number Thermal Stability test device evaluated JP-8 and RP-1 fuels. The experiment consisted of an electrically heated, stainless steel capillary tube with a controlled fuel outlet temperature. An optical pyrometer monitored the increasing external temperature profiles of the capillary tube as deposits build inside during each test. Multiple runs of each fuel composition provided results on measurement repeatability. Testing a t two different facilities provided data on measurement reproducibility. The technique is able to distinguish between thermally stable and unstable compositions of JP-8 and intermediate blends made by combining each composition. The technique is also able to distinguish among standard RP-1 rocket fuels and those having reduced sulfur levels. Carbon burn off analysis of residue in the capillary tubes on the RP-1 fuels correlates with the external temperature results
Effects of Rainfall on E. coli Concentrations at Door County, Wisconsin Beaches
Rainfall and its associated storm water runoff have been associated with transport of many pollutants into beach water. Fecal material, from a variety of animals (humans, pets, livestock, and wildlife), can wash into beach water following rainfall and result in microbial contamination of the beach. Many locales around the world issue pre-emptive beach closures associated with rainfall. This study looked at eight beaches located in Door County, Wisconsin, on Lake Michigan to determine the impact of rainfall on E. coli concentrations in beach water. Water samples were collected from beach water and storm water discharge pipes during rainfall events of 5 mm in the previous 24 hours. Six of the eight beaches showed a significant association between rainfall and elevated beach water E. coli concentrations. The duration of the impact of rainfall on beach water E. coli concentrations was variable (immediate to 12 hours). Amount of rainfall in the days previous to the sampling did not have significant impact on the E. coli concentrations measured in beach water. Presence of storm water conveyance pipes adjacent to the beach did not have a uniform impact on beach water E. coli concentrations. This study suggests that each beach needs to be examined on its own with regard to rain impacts on E coli concentrations in beach water
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