13,173 research outputs found
Lower oil prices and state employment
Employment (Economic theory) ; Power resources ; Petroleum industry and trade
Business cycles: the role of energy prices
Oil price shocks have figured prominently U.S. business cycles since the end of World War II—although the relationship seems to have weakened during the 1990s. In addition the economy appears to respond asymmetrically to oil price shocks, rising oil prices hurt economic activity more than falling oil prices help it. This section of the Encyclopedia of Energy sorts through an extensive economics literature that relates oil price shocks to aggregate economic activity. It examines how oil price shocks create business cycles, why they seem to have a disproportionate effect on economic activity, why the economy responds asymmetrically to oil prices, and why the relationship between oil prices and economic activity may have weakened. It also addresses the issue of developing energy policy to mitigate the economic effects of oil price shocks.Petroleum industry and trade
Three-dimensional Keplerian orbit-superposition models of the nucleus of M31
We present three-dimensional eccentric disc models of the nucleus of M31,
modelling the disc as a linear combination of thick rings of massless stars
orbiting in the potential of a central black hole. Our models are nonparametric
generalisations of the parametric models of Peiris & Tremaine. The models
reproduce well the observed WFPC2 photometry, the detailed line-of-sight
velocity distributions from STIS observations along P1 and P2, together with
the qualitative features of the OASIS kinematic maps. We confirm Peiris &
Tremaine's finding that nuclear discs aligned with the larger disc of M31 are
strongly ruled out. Our optimal model is inclined at 57 degrees with respect to
the line of sight of M31 and has a position angle of 55 degrees. It has a
central black hole of mass 10^8 solar masses, and, when viewed in three
dimensions, shows a clear enhancement in the density of stars around the black
hole. The distribution of orbit eccentricities in our models is similar to
Peiris & Tremaine's model, but we find significantly different inclination
distributions, which might provide valuable clues to the origin of the disc.Comment: 13 pages, 14 figures. MNRAS, in pres
Computational design of low aspect ratio wing-winglet configurations for transonic wind-tunnel tests
A computational design has been performed for three different low aspect ratio wing planforms fitted with nonplanar winglets; one of the three planforms has been selected to be constructed as a wind tunnel model for testing in the NASA LaRC 7 x 10 High Speed Wind Tunnel. A design point of M = 0.8, CL approx = 0.3 was selected, for wings of aspect ratio equal to 2.2, and leading edge sweep angles of 45 and 50 deg. Winglet length is 15 percent of the wing semispan, with a cant angle of 15 deg, and a leading edge sweep of 50 deg. Winglet total area equals 2.25 percent of the wing reference area. This report summarizes the design process and the predicted transonic performance for each configuration
Sociology of low expectations: Recalibration as innovation work in biomedicine
"This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm). "Social scientists have drawn attention to the role of hype and optimistic visions of the future in providing momentum to biomedical innovation projects by encouraging innovation alliances. In this article, we show how less optimistic, uncertain, and modest visions of the future can also provide innovation projects with momentum. Scholars have highlighted the need for clinicians to carefully manage the expectations of their prospective patients. Using the example of a pioneering clinical team providing deep brain stimulation to children and young people with movement disorders, we show how clinicians confront this requirement by drawing on their professional knowledge and clinical expertise to construct visions of the future with their prospective patients; visions which are personalized, modest, and tainted with uncertainty. We refer to this vision-constructing work as recalibration, and we argue that recalibration enables clinicians to manage the tension between the highly optimistic and hyped visions of the future that surround novel biomedical interventions, and the exigencies of delivering those interventions in a clinical setting. Drawing on work from science and technology studies, we suggest that recalibration enrolls patients in an innovation alliance by creating a shared understanding of how the “effectiveness” of an innovation shall be judged.This project was funded by the Wellcome Trust (Wellcome Trust Biomedical Strategic Award 086034)
A cancer cell-line titration series for evaluating somatic classification.
BackgroundAccurate detection of somatic single nucleotide variants and small insertions and deletions from DNA sequencing experiments of tumour-normal pairs is a challenging task. Tumour samples are often contaminated with normal cells confounding the available evidence for the somatic variants. Furthermore, tumours are heterogeneous so sub-clonal variants are observed at reduced allele frequencies. We present here a cell-line titration series dataset that can be used to evaluate somatic variant calling pipelines with the goal of reliably calling true somatic mutations at low allele frequencies.ResultsCell-line DNA was mixed with matched normal DNA at 8 different ratios to generate samples with known tumour cellularities, and exome sequenced on Illumina HiSeq to depths of >300Ă—. The data was processed with several different variant calling pipelines and verification experiments were performed to assay >1500 somatic variant candidates using Ion Torrent PGM as an orthogonal technology. By examining the variants called at varying cellularities and depths of coverage, we show that the best performing pipelines are able to maintain a high level of precision at any cellularity. In addition, we estimate the number of true somatic variants undetected as cellularity and coverage decrease.ConclusionsOur cell-line titration series dataset, along with the associated verification results, was effective for this evaluation and will serve as a valuable dataset for future somatic calling algorithm development. The data is available for further analysis at the European Genome-phenome Archive under accession number EGAS00001001016. Data access requires registration through the International Cancer Genome Consortium's Data Access Compliance Office (ICGC DACO)
Chemisorption studies of Pt/SnO2 catalysts
The low temperature CO oxidation catalysts that are being developed and tested at NASA-Langley are fairly unique in their ability to efficiently oxidize CO at low temperatures (approx. 303 K). The bulk of the reaction data that has been collected in the laboratory has been determined using plug flow reactors with a low mass of Pt/SnO2/SiO2 catalyst (approx. 0.1 g) and a modest flow rate (5 to 10 sc sm). The researchers have previously characterized the surface solely in terms of N2 BET surface areas. These surface areas have not been that indicative of reaction rate. Indeed, some of the formulations with high BET surface area have yielded lower reaction rates than those with lower BET surface areas. As a result researchers began a program of determining the chemisorption of the various species involved in the reaction; CO, O2 and CO2. Such a determination of will lead to a better understanding of the mechanism and overall kinetics of the reaction. The pulsed-reactor technique, initially described by Freel, is used to determine the amount of a particular molecule that is adsorbed on the catalyst. Since there is some reaction of CO with the surface to produce CO2, the pulsed reactor had to be coupled with a gas chromatograph in order to distinguish between the loss of CO that is due to adsorption by the surface and the loss that is due to reaction with the surface
Evaluate Naturally and Quickly with Just-in-Time Program Evaluation
A just-in-time evaluation approach can help Extension professionals expand their program evaluation readiness, interest, and competence. A pilot test of this efficient approach helped organizers of a forest farming conference determine important information about the event\u27s processes and content to be better positioned for future work. The conference evaluation team and conference participants enjoyed this approach that integrated evaluation methods and evaluative thinking into all the conference activities. This approach to evaluation is especially appropriate for gathering real-time data for determining the value of educational processes taking place while making evaluation more visible and easier to accomplish
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