BEM-ESTAR ANIMAL: CONCEITO E QUESTÕES RELACIONADAS REVISÃO

Bem-estar é um termo de uso corrente em várias situações e seu significado geralmente não é preciso. Entretanto, definição objetiva de bem-estar faz-se necessária para a utilização científica e profissional do conceito. Bem-estar deve ser definido de forma que permita pronta relação com outros conceitos, tais como: necessidades, liberdades, felicidade, adaptação, controle, capacidade de previsão, sentimentos, sofrimento, dor, ansiedade, medo, tédio, estresse e saúde. Objetiva-se na revisão apresentar uma definição de bem-estar animal atendendo os critérios mencionados, associada a uma explicação sobre a avaliação do bem-estar animal. Espera-se oferecer ao leitor uma base para o entendimento desta nova ciência, indispensável aos profissionais cujo trabalho gira em torno da interação entre seres humanos e animais. Animal welfare: concept and related issues Review Abstract Welfare is a word widely used by public in many situations and its meaning is often not precise. However, an objective definition is needed if the concept is to be used scientifically and professionally. Moreover, welfare has to be defined in such a way that it can be readily related to other concepts such as: needs, freedoms, happiness, coping, control, predictability, feelings, suffering, pain, anxiety, fear, boredom, stress and health. This review presents a definition of animal welfare which satisfies these criteria, as well as explaining how to assess welfare. Its main objective is to offer the reader a basis for an understanding of this new science, which is essential to those whose work centres on the human-animal interaction

Longitudinal effects of environmental enrichment on behaviour and physiology of pigs reared on an intensive-stock farm

The aim of this paper was to provide a longitudinal evaluation of the effects of physical enrichments on the behaviour and physiology of intensive stock-farming pigs. Twenty-eight crossbred pigs of both sexes, were exposed to four types of enrichments (hemp ropes, steel chains, plastic balls, rubber hoses) over a period of eleven weeks. This investigation was based on specific abnormal behaviours and physiological indicators, including hematologic parameters. For behavioural score, focal sampling was used with recording of abnormal behaviours (body-, tail- and ear-biting), belly nosing, running, and interaction with objects (for Enriched pigs). The presence of skin injuries was also recorded. In general, the frequency of abnormal behaviours was significantly reduced in the Enriched group. A timerelated profile appeared in the use of the enrichments. Males showed higher occurrence of skin injuries than females. Physiological measurements, such as levels of complement system, white blood cells and neutrophils, were lower in pigs from the Enriched group. Enriched pigs, as a whole, presented much lower levels of serum DHEA-S concentration over two weeks. The findings of this study show the successful provision of appropriate enrichments to encourage behaviours which may result in satisfactory animal oral interaction with the enriching objects, preventing them biting pen-mates. In this respect, the objects proposed were strongly effective in producing changes in behaviour which could mitigate inadequate conditions, such as the relationship between animal body weight and the available space allowance

Effect of summer grazing on welfare of dairy cows reared in mountain tie-stall barns

Traditional mountain farms have an important economic, social and environmental role. The Alps management system for dairy cows consists of animals kept indoors from autumn to spring, mostly in tie-stalls, and moved to mountain pasture in summer. The aim of our study was to assess the effect of mountain summer grazing on the welfare of dairy cows housed in tie-stall barns. Twenty-four farms were considered. In twelve of them, animals were reared in tie-stalls and moved to mountain pasture for three months in summer; they were visited three times: (i) four weeks before grazing during the indoor period in the stall; (ii) about three weeks after the start of grazing; and (iii) in the stall, in autumn, at least three weeks after returning from grazing. The other twelve farms kept the animals in tie-stalls all year; they were visited once in autumn. Data were collected following a protocol that considers animal-based measures and structure information on the basis of Quality Welfare Consortium® indications. Data allowed the calculation of both the Animal Needs Index score (ANI 35L) and an overall assessment of the cows' welfare obtained from three general aspects: housing, animal's physical condition, and animal's behaviour. Summer grazing had a significant positive effect on injuries, lameness and animal's rising duration but a negative effect on faeces consistency. Moreover, a reduction of tongue playing was observed. The ANI 35L and the overall assessment did not show significant differences linked to summer grazing, which tended to have a positive but temporary effect on animal behaviour

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types