8,059 research outputs found

    The Second Coming Of The Invisible Empire: The Ku Klux Klan Of The 1920s

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    Invisible Empire\u27s Visible Reach in Georgia The Ku Klux Klan, a terrorist group with its origins in the Reconstruction era after the Civil War, reemerged as a wildly popular organization in the 1920s. The Klan\u27s ability to enroll millions of dues-paying Americans in its ranks owed much to the sophi...

    Mckenzie Evaluation and Treatment for Lumbar Dysfunction and ANR

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    Background and Purpose: When it comes to low back pain, McKenzie theory is considered highly effective for evaluating and treating patients with low back symptoms. There are three main classifications within McKenzie theory; postural, dysfunction, and derangement syndromes. The main focus of this case will be on the dysfunction classification and its subcategory adherent nerve roots (ANR). Dysfunction syndrome is characterized by pain due to deformation of structures and tissues that limit ROM causing pain at end range. ANR\u27s are caused by scar tissue build up encompassing nerve roots due to trauma or surgery that produces symptoms when nerve tension is present. Case Description: The patient is a 32 year old male who presents with low back pain which later was diagnosed as a lumbar extension dysfunction and RlE ANR. Interventions: Treatment focused on correction of dysfunction and ANR through prone press ups and nerve flossing. Treatment goals were to decrease pain, increase spinal ROM, and improve functional abilities. Outcomes: Treatment lasted 9 weeks from initial evaluation with a total of 10 visits. Upon discharge the patient displayed full and pain-free spinal ROM in all directions with SlR, and slump test being negative with improved functional mobility at home and work. Discussion: The patient reported high satisfaction with treatment outcomes. Additional studies would be beneficial due to limited research in the area of ANR\u27s and dysfunctions

    Transcriptional Analysis of Reciprocal Tumor-Microenvironment Interactions in Glioblastoma

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    In the last twenty years both computational biology and cancer biology have made great strides and in the last 5 years the merger of the two has helped to revolutionize our knowledge of personalized targeted therapy and the diversity of cancer. In cancer, cell-to-cell interactions between tumor cells and their microenvironment are critical determinants of tumor tissue biology and therapeutic responses. Interactions between glioblastoma (GBM) cells and endothelial cells (ECs) establish a purported stem cell niche. We hypothesized that genes that mediate these interactions would be important, particularly as therapeutic targets. Using a novel computational approach to deconvoluting expression data from mixed physical coculture of GBM cells and ECs, we identified a previously undescribed upregulation of the cAMP specific phosphodiesterase PDE7B in GBM cells in response to ECs. We further found that elevated PDE7B expression occurs in most GBM cases and has a negative effect on survival. PDE7B overexpression resulted in the expansion of a stem-like cell subpopulation, increased tumor aggressiveness, and increased growth in an intracranial GBM model. This deconvolution algorithm provides a new tool for cancer biology, particularly when looking at cell-to-cell interactions, and these results identify PDE7B as a therapeutic target in GBM

    Cosmetic Talc-Related Pulmonary Granulomatosis.

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    Inhalation of cosmetic talc can lead to pulmonary foreign-body granulomatosis, though fewer than 10 cases of inhaled cosmetic talc-related pulmonary granulomatosis have been reported in adults. We report the case of a 64-year-old man with diffuse, bilateral pulmonary nodules and ground glass opacities associated with chronic inhalation of cosmetic talc. Transbronchial biopsy showed peribronchiolar foreign-body granulomas. After cessation of talc exposure, the patient demonstrated clinical and radiographic improvement without the use of corticosteroids. This case demonstrates that a conservative approach with cessation of exposure alone, without the use of corticosteroids, can be an effective therapy in cosmetic talc-related pulmonary granulomatosis

    Induced quasi-cocycles on groups with hyperbolically embedded subgroups

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    Let G be a group, H a hyperbolically embedded subgroup of G, V a normed G-module, U an H-invariant submodule of V. We propose a general construction which allows to extend 1-quasi-cocycles on H with values in U to 1-quasi-cocycles on G with values in V. As an application, we show that every group G with a non-degenerate hyperbolically embedded subgroup has dim H^2_b (G, l^p(G))=\infty for p\in [1, \infty). This covers many previously known results in a uniform way. Applying our extension to quasimorphisms and using Bavard duality, we also show that hyperbolically embedded subgroups are undistorted with respect to the stable commutator length.Comment: 27 pages, 6 figure

    Comparison of the Effects of 97 Per Cent and 21 Per Cent Oxygen Mixtures Upon Recovery From Treadmill Running Among Male Wrestlers at Utah State University

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    A comparison of the effects on recovery while breathing a 97 per cent oxygen mixture and normal compressed atmospheric air after treadmill running was determined among nine male wrestlers at Utah State University. The variables examined were heart rate and percentages of oxygen and carbon dioxide in expired air. The practice of some athletic teams of administering oxygen to participants during time out periods was the motivation for this study. A great majority of the studies reviewed conclude that oxygen does not play a significant role in aiding recovery from physical activity. The experiment first consisted of eight runs on the treadmill (Quinton Model 18-49-C) to familiarize the subjects with the equipment and also to enable them to plateau in conditioning for a five minute run at 0 per cent grade at eight miles per hour. After the training period was completed, the nine subjects went through a series of six runs, each followed immediately by a five minute recovery period while breathing a 97 per cent oxygen mixture for three of the recovery periods, and a 21 per cent oxygen mixture for the other three recovery periods. Heart rate was recorded every 30 seconds during the recovery period by the use of three electrodes on the subjects. Expired air was collected with the use of the Kofrany-Michaelis Respirometer. Air samples were analyzed for percentages of oxygen and carbon dioxide by the Fry Gas Analyzer. An analysis of variance showed no significant difference in heart rate decline while breathing either gas mixture. At the end of the five minutes of recovery, the subjects expired 3 per cent of carbon dioxide regardless of which oxygen mixture was breathed. It was concluded that there were no significant differences in the effects on recovery while breathing the 97 per cent oxygen mixture or the 21 per cent oxygen mixture
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