Symmetric M-ary phase discrimination using quantum-optical probe states

We present a theoretical study of minimum error probability discrimination, using quantum- optical probe states, of M optical phase shifts situated symmetrically on the unit circle. We assume ideal lossless conditions and full freedom for implementing quantum measurements and for probe state selection, subject only to a constraint on the average energy, i.e., photon number. In particular, the probe state is allowed to have any number of signal and ancillary modes, and to be pure or mixed. Our results are based on a simple criterion that partitions the set of pure probe states into equivalence classes with the same error probability performance. Under an energy constraint, we find the explicit form of the state that minimizes the error probability. This state is an unentangled but nonclassical single-mode state. The error performance of the optimal state is compared with several standard states in quantum optics. We also show that discrimination with zero error is possible only beyond a threshold energy of (M - 1)/2. For the M = 2 case, we show that the optimum performance is readily demonstrable with current technology. While transmission loss and detector inefficiencies lead to a nonzero erasure probability, the error rate conditional on no erasure is shown to remain the same as the optimal lossless error rate.Comment: 13 pages, 10 figure

Low-Temperature Spin Diffusion in a Spin-Polarized Fermi Gas

We present a finite temperature calculation of the transverse spin-diffusion coefficient, $D_\bot$, in a dilute degenerate Fermi gas in the presence of a small external magnetic field, $H$. While the longitudinal diffusion coefficient displays the conventional low-temperature Fermi-liquid behavior, $D_\parallel \propto T^{-2}$, the corresponding results for $D_\bot$ show three separate regimes: (a) $D_\bot \sim H^{-2}$ for $T \ll H$; (b) $D_\bot \sim T^{-2}$, $D_\bot /D_\parallel \neq 1$ for $T \gg H$ and large spin-rotation parameter $\xi \gg 1$, and (c) $D_\bot = D_\parallel \propto T^{-2}$ for $T \gg H$ and $\xi \ll 1$. Our results are qualitatively consistent with the available experimental data in weakly spin-polarized $^3{\rm He}$ and $^3{\rm He} - ^4{\rm He}$ mixtures.Comment: 13 pages, REVTEX, 3 figures available upon request, RU-94-4

Electrical Conductivity of Fermi Liquids. II. Quasiparticle Transport

We develop a general theory of Fermi liquids to discuss the Kadowaki-Woods relation $A\propto \gamma^2$. We derive a formula for the ratio $A/\gamma^2$ which is expressed as a product of two dimensionless parameters $\alpha$ and $F$, where $\alpha$ represents a coupling constant for quasiparticle scattering and $F$ is a geometric factor determined by the shape of the Fermi surface. Then we argue that the universal ratio observed in heavy fermion compounds is reproduced under the conditions $\alpha\sim 1$ and $F\sim 20$. The former is regarded as a universality of Fermi liquids in a strong coupling regime, and the latter is corroborated by evaluating $F$ definitely in simple cases. It is noted that the proportional relation is just an example of the universal phenomena to be expected for the whole class of strong coupling Fermi liquids.Comment: 28 pages, 7 figures; J. Phys. Soc. Jpn. Vol.67, No.1

Spatial distribution of podoconiosis in relation to environmental factors in Ethiopia: a historical review

BACKGROUND An up-to-date and reliable map of podoconiosis is needed to design geographically targeted and cost-effective intervention in Ethiopia. Identifying the ecological correlates of the distribution of podoconiosis is the first step for distribution and risk maps. The objective of this study was to investigate the spatial distribution and ecological correlates of podoconiosis using historical and contemporary survey data. METHODS Data on the observed prevalence of podoconiosis were abstracted from published and unpublished literature into a standardized database, according to strict inclusion and exclusion criteria. In total, 10 studies conducted between 1969 and 2012 were included, and data were available for 401,674 individuals older than 15 years of age from 229 locations. A range of high resolution environmental factors were investigated to determine their association with podoconiosis prevalence, using logistic regression. RESULTS The prevalence of podoconiosis in Ethiopia was estimated at 3.4% (95% CI 3.3%-3.4%) with marked regional variation. We identified significant associations between mean annual Land Surface Temperature (LST), mean annual precipitation, topography of the land and fine soil texture and high prevalence of podoconiosis. The derived maps indicate both widespread occurrence of podoconiosis and a marked variability in prevalence of podoconiosis, with prevalence typically highest at altitudes >1500 m above sea level (masl), with >1500 mm annual rainfall and mean annual LST of 19-21°C. No (or very little) podoconiosis occurred at altitudes 24°C. CONCLUSION Podoconiosis remains a public health problem in Ethiopia over considerable areas of the country, but exhibits marked geographical variation associated in part with key environmental factors. This is work in progress and the results presented here will be refined in future work

Sound modes in hot nuclear matter

The propagation of the isoscalar and isovector sound modes in a hot nuclear matter is considered. The approach is based on the collisional kinetic theory and takes into account the temperature and memory effects. It is shown that the sound velocity and the attenuation coefficient are significantly influenced by the Fermi surface distortion (FSD). The corresponding influence is much stronger for the isoscalar mode than for the isovector one. The memory effects cause a non-monotonous behavior of the attenuation coefficient as a function of the relaxation time leading to a zero-to-first sound transition with increasing temperature. The mixing of both the isoscalar and the isovector sound modes in an asymmetric nuclear matter is evaluated. The condition for the bulk instability and the instability growth rate in the presence of the memory effects is studied. It is shown that both the FSD and the relaxation processes lead to a shift of the maximum of the instability growth rate to the longer wave length region.Comment: 15 pages, 4 figures, submitted to Phys. Rev.

Interactions and potential implications of Plasmodium falciparum-hookworm coinfection in different age groups in south-central Côte d'Ivoire

BACKGROUND: Given the widespread distribution of Plasmodium and helminth infections, and similarities of ecological requirements for disease transmission, coinfection is a common phenomenon in sub-Saharan Africa and elsewhere in the tropics. Interactions of Plasmodium falciparum and soil-transmitted helminths, including immunological responses and clinical outcomes of the host, need further scientific inquiry. Understanding the complex interactions between these parasitic infections is of public health relevance considering that control measures targeting malaria and helminthiases are going to scale.METHODOLOGY: A cross-sectional survey was carried out in April 2010 in infants, young school-aged children, and young non-pregnant women in south-central Côte d'Ivoire. Stool, urine, and blood samples were collected and subjected to standardized, quality-controlled methods. Soil-transmitted helminth infections were identified and quantified in stool. Finger-prick blood samples were used to determine Plasmodium spp. infection, parasitemia, and hemoglobin concentrations. Iron, vitamin A, riboflavin, and inflammation status were measured in venous blood samples.PRINCIPAL FINDINGS: Multivariate regression analysis revealed specific association between infection and demographic, socioeconomic, host inflammatory and nutritional factors. Non-pregnant women infected with P. falciparum had significantly lower odds of hookworm infection, whilst a significant positive association was found between both parasitic infections in 6- to 8-year-old children. Coinfected children had lower odds of anemia and iron deficiency than their counterparts infected with P. falciparum alone.CONCLUSIONS/SIGNIFICANCE: Our findings suggest that interaction between P. falciparum and light-intensity hookworm infections vary with age and, in school-aged children, may benefit the host through preventing iron deficiency anemia. This observation warrants additional investigation to elucidate the mechanisms and consequences of coinfections, as this information could have important implications when implementing integrated control measures against malaria and helminthiases

Ein neues, unkompliziertes Verfahren zur Bestimmung der Zusammensetzung binärer Flüssigkeitsgemische

Ein neues Verfahren zur Bestimmung der Zusammensetzung binärer Flüssigkeitsgemische mit Hilfe solvatochromer Farbstoffe wird beschrieben. Die Analyse erfolgt durch einfache UV/VIS-Absorptionsmessung und ist unter Verwendung einer Zwei-Parameter-Gleichung ein exakter Schnelltest

Spatial and Genetic Epidemiology of Hookworm in a Rural Community in Uganda

There are remarkably few contemporary, population-based studies of intestinal nematode infection for sub-Saharan Africa. This paper presents a comprehensive epidemiological analysis of hookworm infection intensity in a rural Ugandan community. Demographic, kinship, socioeconomic and environmental data were collected for 1,803 individuals aged six months to 85 years in 341 households in a cross-sectional community survey. Hookworm infection was assessed by faecal egg count. Spatial variation in the intensity of infection was assessed using a Bayesian negative binomial spatial regression model and the proportion of variation explained by host additive genetics (heritability) and common domestic environment was estimated using genetic variance component analysis. Overall, the prevalence of hookworm was 39.3%, with the majority of infections (87.7%) of light intensity (≤1000 eggs per gram faeces). Intensity was higher among older individuals and was associated with treatment history with anthelmintics, walking barefoot outside the home, living in a household with a mud floor and education level of the household head. Infection intensity also exhibited significant household and spatial clustering: the range of spatial correlation was estimated to be 82 m and was reduced by a half over a distance of 19 m. Heritability of hookworm egg count was 11.2%, whilst the percentage of variance explained by unidentified domestic effects was 17.8%. In conclusion, we suggest that host genetic relatedness is not a major determinant of infection intensity in this community, with exposure-related factors playing a greater role

Assessment of breast pathologies using nonlinear microscopy

Rapid intraoperative assessment of breast excision specimens is clinically important because up to 40% of patients undergoing breast-conserving cancer surgery require reexcision for positive or close margins. We demonstrate nonlinear microscopy (NLM) for the assessment of benign and malignant breast pathologies in fresh surgical specimens. A total of 179 specimens from 50 patients was imaged with NLM using rapid extrinsic nuclear staining with acridine orange and intrinsic second harmonic contrast generation from collagen. Imaging was performed on fresh, intact specimens without the need for fixation, embedding, and sectioning required for conventional histopathology. A visualization method to aid pathological interpretation is presented that maps NLM contrast from two-photon fluorescence and second harmonic signals to features closely resembling histopathology using hematoxylin and eosin staining. Mosaicking is used to overcome trade-offs between resolution and field of view, enabling imaging of subcellular features over square-centimeter specimens. After NLM examination, specimens were processed for standard paraffin-embedded histology using a protocol that coregistered histological sections to NLM images for paired assessment. Blinded NLM reading by three pathologists achieved 95.4% sensitivity and 93.3% specificity, compared with paraffin-embedded histology, for identifying invasive cancer and ductal carcinoma in situ versus benign breast tissue. Interobserver agreement was κ = 0.88 for NLM and κ = 0.89 for histology. These results show that NLM achieves high diagnostic accuracy, can be rapidly performed on unfixed specimens, and is a promising method for intraoperative margin assessment.National Institutes of Health (U.S.) (Grant R01-CA178636-01)National Institutes of Health (U.S.) (Grant R01-CA75289-16)United States. Air Force Office of Scientific Research (Grant FA9550-10-1-0551)United States. Air Force Office of Scientific Research (Grant FA9550-12-1-0499)National Institutes of Health (U.S.) (National Research Service Award Postdoctoral Fellowship F32-CA165484