The prediction and measurement of sound radiated by structures

Theories regarding the radiation of sound are reviewed and the implementation in strategies for explaining or measuring the sound produced by practical strucutres are discussed. Particular attention is given to those aspects that relate to the determination of the relative amounts of sound generated by various parts of a machine or structure, which can be very useful information for noise reduction efforts

Freed-Witten anomaly in general flux compactification

Turning on a NS-NS three-form flux in a compact space drives some D-branes to be either Freed-Witten anomalous or unstable to decay into fluxes by the appearance of instantonic branes. By applying T-duality on a toroidal compactification, the NS-flux is transformed into metric fluxes. We propose a T-dual version of the Atiyah-Hirzebruch Spectral Sequence upon which we describe the Freed-Witten anomaly and the brane-flux transition driven by NS and metric fluxes in a twisted torus. The required conditions to cancel the anomaly and the appearance of new instantonic branes are also described. In addition, we give an example in which all D6-branes wrapping Freed-Witten anomaly-free three-cycles in the twisted torus T^6/Z(2)XZ(2) are nevertheless unstable to be transformed into fluxes. Evenmore we find a topological transformation between RR, NS-NS and metric fluxes driven by a chain of instantonic branes.Comment: v3: Shortened version. Examples added. Main results unchange

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: Implication for neuroprotective therapies

Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF levels a reduction of TrkB expression could also contribute to diminished neurotrophic support in HD. BDNF can also bind to p75 neurotrophin receptor (p75(NTR)) modulating TrkB signaling. Therefore, in this study we have analyzed the levels of p75(NTR) in several HD models, as well as in HD human brain. Our data demonstrates a p75(NTR)/TrkB imbalance in the striatum of two different HD mouse models, Hdh(Q111/111) homozygous knockin mice and R6/1 mice that was also manifested in the putamen of HD patients. The imbalance between TrkB and p75(NTR) levels in a HD cellular model did not affect BDNF-mediated TrkB activation of prosurvival pathways but induced activation of apoptotic cascades as demonstrated by increased JNK phosphorylation. Moreover, BDNF failed to protect mutant huntingtin striatal cells transfected with p75(NTR) against NMDA-mediated excitotoxicity, which was associated with decreased Akt phosphorylation. Interestingly, lack of Akt activation following BDNF and NMDA treatment correlated with increased PP1 levels. Accordingly, pharmacological inhibition of PP1 by okadaic acid (OA) prevented mutant huntingtin striatal cell death induced by NMDA and BDNF. Altogether, our findings demonstrate that the p75(NTR)/TrkB imbalance induced by mutant huntingtin in striatal cells associated with the aberrant activity of PP1 disturbs BDNF neuroprotection likely contributing to increasing striatal vulnerability in HD. On the basis of this data we hypothesize that normalization of p75(NTR) and/or TrkB expression or their signaling will improve BDNF neuroprotective therapies in HD. Cell Death and Disease (2013) 4, e595; doi:10.1038/cddis.2013.116; published online 18 April 201

Magnetic states of linear defects in graphene monolayers: effects of strain and interaction

The combined effects of defect-defect interaction and of uniaxial or biaxial strains of up to 10\% on the development of magnetic states on the defect-core-localized quasi-one-dimensional electronic states generated by the so-called 558 linear extended defect in graphene monolayers are investigated by means of {\it ab initio} calculations. Results are analyzed on the basis of the heuristics of the Stoner criterion. We find that conditions for the emergence of magnetic states on the 558 defect can be tuned by uniaxial tensile parallel strains (along the defect direction) at both limits of isolated and interacting 558 defects. Parallel strains are shown to lead to two cooperative effects that favor the emergence of itinerant magnetism: enhancement of the DOS of the resonant defect states in the region of the Fermi level and tuning of the Fermi level to the maximum of the related DOS peak. A perpendicular strain is likewise shown to enhance the DOS of the defect states, but it also effects a detunig of the Fermi level that shifts away from the maximum of the DOS of the defect states, which inhibts the emergence of magnetic states. As a result, under biaxial strains the stabilization of a magnetic state depends on the relative magnitudes of the two components of strain.Comment: 9 pages 8 figure

Perdas economicas decorrentes de diferentes graus de severidade e rinite atrofica em suinos.

bitstream/CNPSA/7661/1/cot169.pdf; bitstream/item/58760/1/CUsersPiazzonDocuments169.pd

Chaotic behavior in a Z_2 x Z_2 field theory

We investigate the presence of chaos in a system of two real scalar fields with discrete Z_2 x Z_2 symmetry. The potential that identify the system is defined with a real parameter r and presents distinct features for r>0 and for r<0. For static field configurations, the system supports two topological sectors for r>0, and only one for r<0. Under the assumption of spatially homogeneous fields, the system exhibts chaotic behavior almost everywhere in parameter space. In particular a more complex dynamics appears for r>0; in this case chaos can decrease for increasing energy, a fact that is absent for r<0.Comment: Revtex, 13 pages, no figures. Version with figures in Int. J. Mod. Phys. A14 (1999) 496

Mesoscale dynamics on the Sun's surface from HINODE observations

Aims: The interactions of velocity scales on the Sun's surface, from granulation to supergranulation are still not understood, nor are their interaction with magnetic fields. We thus aim at giving a better description of dynamics in the mesoscale range which lies between the two scales mentioned above. Method: We analyse a 48h high-resolution time sequence of the quiet Sun photosphere at the disk center obtained with the Solar Optical Telescope onboard Hinode. The observations, which have a field of view of 100 \arcsec$\times$ 100 \arcsec, typically contain four supergranules. We monitor in detail the motion and evolution of granules as well as those of the radial magnetic field. Results: This analysis allows us to better characterize Trees of Fragmenting Granules issued from repeated fragmentation of granules, especially their lifetime statistics. Using floating corks advected by measured velocity fields, we show their crucial role in the advection of the magnetic field and in the build up of the network. Finally, thanks to the long duration of the time series, we estimate that the turbulent diffusion coefficient induced by horizontal motion is approximately $430 \mathrm{km}^2 \mathrm{s}^{-1}$. Conclusions: These results demonstrate that the long living families contribute to the formation of the magnetic network and suggest that supergranulation could be an emergent length scale building up as small magnetic elements are advected and concentrated by TFG flows. Our estimate for the magnetic diffusion associated with this horizontal motion might provide a useful input for mean-field dynamo models.Comment: to appear in A&A - 8 pages, 13 figures (degraded quality) - Full resolution version available @ http://www.ast.obs-mip.fr/users/rincon/hinode_roudier_aa09.pd

Universal scaling dynamics in a perturbed granular gas

We study the response of a granular system at rest to an instantaneous input of energy in a localised region. We present scaling arguments that show that, in $d$ dimensions, the radius of the resulting disturbance increases with time $t$ as $t^{\alpha}$, and the energy decreases as $t^{-\alpha d}$, where the exponent $\alpha=1/(d+1)$ is independent of the coefficient of restitution. We support our arguments with an exact calculation in one dimension and event driven molecular dynamic simulations of hard sphere particles in two and three dimensions.Comment: 5 pages, 5 figure