Designing and Evaluating Playground Equipment for Compliance with the Americans with Disabilities Act

The need for accessible playgrounds is more prevalent than ever before, with approximately 3 million children having disabilities and health issues that limit their ability to partake in play and school. The Americans with Disabilities Act (ADA) recently provided, for the first time, specific accessible design standards for playgrounds. All playgrounds must now comply with these rules that went into place on March 15, 2012. As it is vital that playgrounds undergo the necessary changes to come up to compliance, there is an opportunity to develop an accessible playground design which satisfies all ADA playground standards and requirements. The objective of this project was to design, develop, and analyze an accessible play structure that included; an elevated structure and a ground level component. This project utilized the engineering design process and civil engineering knowledge to develop computer aided drawings of the structures, structural analyses, complete construction plans, material lists, and cost analyses

APPROACHES TO THE STUDY OF GLYCOLIPID BIOCHEMICAL MECHANISMS OF ACTION

With this work I want to give an explanation of the role of glycolipids in biological processes, paying particular attention to their involvement in various biochemical mechanisms. This thesis will be divided into two sections in which I discuss in the first one, the involvement of glycolipids in the process of fertilization and in the second one I will pay attention on a new class of glycolipids that might be involved in immunoregulation processes. In more details in the first section I will provide an overview of the biochemical role of sulfogactosylglicerolipid (SGG), present in the sperm head of different mammalian species, and its involvement in the process of fertilization. Then I will discuss an approach with which one can interfere in this biochemical mechanism focusing on the possibility of using a new class of molecules that permit not only the inhibition of the fertilization process but that can also act against sexually transmitted diseases. In this scenario, then I will focus on the characteristics of antimicrobial peptides, in particular on the family of cathelicidin, and on their possible application in the inhibition of fertilization, by interaction with SGG, and at the same time the prevention of sexually transmitted diseases. In the second section I will discuss on a new class of immunomodulating glycolipids with an atypical structure, produced by symbiotic bacteria in the marine sponge Plakortis Simplex, which releases a unique profile of cytokines. In this scenario, then I will talk about simplexide and on the role in which is involved in the activation of peripheral blood mononuclear cells (PBMC), and the peculiar profile of cytokines released. Then I will describe the synthesis of a fluorescent analogue of simplexide which will be made to evaluate the subcellular distribution of the glycolipid and to clarify its mechanism of action

Soil conservation applications with C-band SAR

Soil conservation programs are becoming more important as the growing human population exerts greater pressure on this non-renewable resource. Indeed, soil degradation affects approximately 10 percent of Canada's agricultural land with an estimated loss of 6,000 hectares of topsoil annually from Ontario farmland alone. Soil loss not only affects agricultural productivity but also decreases water quality and can lead to siltation problems. Thus, there is a growing demand for soil conservation programs and a need to develop an effective monitoring system. Topography and soil type information can easily be handled within a geographic information system (GIS). Information about vegetative cover type and surface roughness, which both experience considerable temporal change, can be obtained from remote sensing techniques. For further development of the technology to produce an operational soil conservation monitoring system, an experiment was conducted in Oxford County, Ontario which investigated the separability of fall surface cover type using C-band Synthetic Aperture Radar (SAR) data

A novel systematic method to evaluate computer supported collaborative design technologies

Selection of suitable computer-supported collaborative design (CSCD) technologies is crucial to facilitate successful projects. This paper presents the first systematic method for engineering design teams to evaluate and select the most suitable CSCD technologies comparing technology functionality and project requirements established in peer-reviewed literature. The paper first presents 220 factors that influence successful CSCD. These factors were then systematically mapped and categorised to create CSCD requirement statements. The novel evaluation and selection method incorporates these requirement statements within a matrix and develops a discourse analysis text processing algorithm with data from collaborative projects to automate the population of how technologies impact the success of CSCD in engineering design teams. This method was validated using data collected across 3 years of a student global design project. The impact of this method is the potential to change the way engineering design teams consider the technology they use and how the selection of appropriate tools impacts the success of their CSCD projects. The development of the CSCD evaluation matrix is the first of its kind enabling a systematic and justifiable comparison and technology selection, with the aim of best supporting the engineering designers collaborative design activity

Modelling the relationship between design activity and computer-supported collaborative design factors

Computer-Supported Collaborative Design (CSCD) technologies can enable teams to collaborate across boundaries. Emerging research documents the potential of CSCD technologies to contribute towards successful collaborative design, however, no model exists to define the relationship between a successful design activity and CSCD factors which influence its success. This paper utilises a systematic literature review to categorise known CSCD factors, categorise and characterise them, and applies this knowledge towards developing an established design activity model to include CSCD factors

Effect of Sitting Posture on Development of Scoliosis in Duchenne Muscular Dystrophy Cases

Background: Scoliosis is a frequent association in boys with Duchenne Muscular Dystrophy when the ability to walk is lost around nine to 12 years of age. This study assessed the contribution of physical factors including lumbar posture to scoliosis in non-ambulatory youth with DMD in Nepal. Methods: Linear regression was used to assess effects of time since loss of ambulation, muscle strength, functional severity and lumbar angle as a binary variable on coronal Cobb angle; again logistic regression was used to assess effects of muscle strength and cross-legged sitting on the presence of a lordotic lumbar posture in 22 non-ambulant boys and young men. Results: The boys and young men had a mean (SD) age of 15.1 (4.0) years, had been non-ambulant for 48.6 (33.8) months and used a median of 3.5 (range 2 to 7) postures a day. The mean Cobb angle was 15.1 (range 0 to 70) degrees. Optimal accuracy in predicting scoliosis was obtained with a lumbar angle of -6° as measured by skin markers, and both a lumbar angle ≤-6° (P=0.112) and better functional ability (P=0.102) were associated with less scoliosis. Use of cross-legged sitting postures during the day was associated with a lumbar angle ≤-6° (OR 0.061; 95% CI 0.005 - 0.672; P=0.022). Conclusions: Use of cross-legged sitting posture was associated with increase in lumbar lordosis. Higher angle of lumbar lordosis and better functional ability are associated with lesser degree of scoliosis

satellite technologies to support the sustainability of agricultural production

Precision farming is a form of multidisciplinary and technologically advanced agriculture, which recourses to machines equipped with "intelligent systems," able to dose the productive factors (fertilizers, pesticides, etc.) according to the real needs of the homogeneous areas constituent to the plot (Verhagen and Bouma, Modeling soil variability. In: Pierce FJ, Sadler EJ (eds) The state of site specific management for agriculture. ASA Publications, 1997)

Incorporation of Eye-Tracking and Gaze Feedback to Characterize and Improve Radiologist Search Patterns of Chest X-rays: A Randomized Controlled Clinical Trial

Diagnostic errors in radiology often occur due to incomplete visual assessments by radiologists, despite their knowledge of predicting disease classes. This insufficiency is possibly linked to the absence of required training in search patterns. Additionally, radiologists lack consistent feedback on their visual search patterns, relying on ad-hoc strategies and peer input to minimize errors and enhance efficiency, leading to suboptimal patterns and potential false negatives. This study aimed to use eye-tracking technology to analyze radiologist search patterns, quantify performance using established metrics, and assess the impact of an automated feedback-driven educational framework on detection accuracy. Ten residents participated in a controlled trial focused on detecting suspicious pulmonary nodules. They were divided into an intervention group (received automated feedback) and a control group. Results showed that the intervention group exhibited a 38.89% absolute improvement in detecting suspicious-for-cancer nodules, surpassing the control group's improvement (5.56%, p-value=0.006). Improvement was more rapid over the four training sessions (p-value=0.0001). However, other metrics such as speed, search pattern heterogeneity, distractions, and coverage did not show significant changes. In conclusion, implementing an automated feedback-driven educational framework improved radiologist accuracy in detecting suspicious nodules. The study underscores the potential of such systems in enhancing diagnostic performance and reducing errors. Further research and broader implementation are needed to consolidate these promising results and develop effective training strategies for radiologists, ultimately benefiting patient outcomes.Comment: Submitted for Review in the Journal of the American College of Radiology (JACR