Sarcoidosis and sacroiliitis, a case report

Producción CientíficaSarcoidosis is amultisystem disorder of unknown etiology characterized by the presence of non-caseating granulomas in the organs affected. Sarcoid arthropathy is a rare manifestation, and sacroiliitis is an unusual first manifestation of the disorde

Cuando comer se convierte en un problema

Diabetic gastroparesis is a complication characterized by the slowing of gastric emptying without mechanical obstruction that affects the morbidity and quality of life of patients. Between 5 and 12% of patients present symptoms suggestive of gastroparesis that are maintained over time. The pathogenic mechanisms are not yet clear but they involve nerve alterations at the level of enteric cells, interstitial cells of Cajal and the vagus nerve. Management must be multidisciplinary, including nutritional status, symptom control and the implementation of glycemic control and gastric emptying with new therapies such as electrostimulation.La  gastroparesia diabética es una complicación caracterizada por el enlentecimiento del vaciamiento gástrico sin obstrucción mecánica que afecta a la morbilidad y calidad de vida de los pacientes. Entre el 5-12% de los pacientes presentan síntomas sugestivos de gastroparesia que se mantienen en el tiempo. Los mecanismos patogénicos aún no están claros pero implican alteraciones nerviosas a nivel de células entéricas, células intersticiales de Cajal y el nervio vago. El manejo debe ser multidisciplinar, incluyendo el estado nutricional, el control de síntomas y la implementación del control glucémico y vaciado gástrico con nuevas terapias como la electroestimulación

Lo que la diabetes esconde

Diabetes mellitus (DM) has been associated with various tumor processes. There are several risk factors for pancreatic cancer and it is estimated that 1% of those over 50 years of age, with a recent diagnosis of DM, will develop a pancreatic neoplasm that is usually advanced. Early diagnosis remains key in the prognosis and it may be cost-effective to perform an abdominal CT scan of early screening in adults newly diagnosed with DM. We present the case of a man with a recent diagnosis of DM and a finding of adenocarcinoma of the pancreas with a narrow temporal presentation between both entities.La diabetes mellitus (DM) se ha asociado a diferentes procesos tumorales. Existen diversos factores de riesgo de cáncer de páncreas y se estima que el 1% de los mayores de 50 años con diagnóstico reciente de DM desarrollará una neoplasia pancreática que habitualmente se encuentra en estadio avanzado. El diagnóstico precoz sigue siendo clave en el pronóstico y puede ser rentable la realización de TAC abdominal de cribado temprano en adultos recién diagnosticados de DM. Presentamos el caso de un varón con diagnóstico reciente de DM y hallazgo de adenocarcinoma de páncreas con una estrecha presentación temporal entre ambas entidades

Depression and health related quality of life among HIV-infected people

Producción CientíficaLittle is known about the impact of comorbid psychiatric symptoms in health related quality of life (HRQL) in patients with HIV infection. The aim of this investigation was to describe depressive symptoms and the impact in HRQL in HIV infected people. A cross-sectional study over 150 HIV-outpatients in a tertiary hospital was designed. Depression data were obtained using the Beck Depression Inventory, Second Edition (BDI-II) inventory. HRQL data were collected by disease-specific questionnaire MOS-HIV. Researchers' team designed a specific template to get rest of the data. Almost three-quarters of the population were men. After adjusting for gender and age, HIV-related symptoms and presence of depression were found to be negatively associated with all the Medical Outcomes Study HIV Health Survey (MOS-HIV) general domains and in the Physical Health Summary score and Mental Health Summary score. Optimization of HRQL is particularly important now that HIV is a chronic disease with the prospect of long-term survival. Quality of life and depression should be monitored in follow-up of HIV infected patients. Comorbid psychiatric conditions may serve as markers for impaired functioning and well-being in persons with HIV