Comparative study of voice print Based acoustic features: MFCC and LPCC

Voice is the best biometric feature for investigation and authentication. It has both biological and behavioural features. The acoustic features are related to the voice. The Speaker Recognition System is designed for the automatic authentication of speaker's identity which is truly based on the human's voice. Mel Frequency Cepstrum coefficient (MFCC) and Linear Prediction Cepstrum coefficient (LPCC) are taken in use for feature extraction from the provided voice sample. This paper provides a comparative study of MFCC and LPCC based on the accuracy of results and their working methodology. The results are better if MFCC is used for feature extraction

Health And Social Status Of Senior Citizens In Rural Areas

Research Problem: What is the quality of life of the elderly people, as also the available support system, in rural areas? Objectives:i) To determine the demographic profile of eld­erly ii) To assess the socio-economic, nutritional, health, morbidity and dependency status, and health care utilization. Study Design: Population based cross sectional study. Setting: Community Development   Block - Lakhanmajra Participants: Persons above the age of 65 years. Sample Size: 809 elderly above the age of 65 years. Study Variables: Demographic profile, Literacy, Oc­cupation, Health, Nutrition, Mobility, Dependency, Substance abuse, Support system. Statistical Analysis: By simple proportions. Result: In this study, majority ofthe elderly were self reliant and mobile, being an asset to the family and led socially useful and productive lives. Their pre­dominant problems were visual impairment, joint pains, respiratory diseases and hearing impairment. Joint family and government pension was the major support system to the elderly. However, there is an imperative need to organize education, training and special service programmes for the elderly at the village level

Study of various reasons for interruption of anti-tubercular treatment in patients of tuberculosis reporting to tertiary care center of west Rajasthan

Background: Tuberculosis is a major cause of death in India. Premature cessation of treatment in tuberculosis patient is a leading cause for developing MDR (multidrug resistant tuberculosis) as well as a major threat to control programs. Despite the easy approach and free of cost, availability to antitubercular medicines the interruptions of the treatment are still on a high. So, we analyzed  such various reasons  leading to interrupt the antitubercular treatment.Methods: Total 150 patients who interrupted the antitubercular treatment, were interviewed with a predesigned questionnaire and the result was analyzed.Results: Out of total 150 patients 115 (76.7%)  male and 35 (23.3%)  female were interviewed, who were  having  history of antitubercular treatment interruption. Out of 150 patients, 79 (52.7%) patients stopped their treatment because of improvement. Total 25 (16.7%) patients had stopped their treatment because of high cost, 16 (10.7%) due to personal/family reason, 17 (11.4%) patients had stopped their treatment due to nausea/vomiting/anorexia, 5 (3.3%) due to alcoholism/drug or other addiction, 2 (1.3%) patients  had stopped their treatment because they were advised to stop it  by health personnel and long distance travelled to take drugs.Conclusions: Improvement of symptoms was  the most common reason  in patients who received DOTS treatment and high cost of treatment in patients who received non DOTS treatment. Poor education and socioeconomic status of society are the other reasons for possible treatment interruptions because as soon as the patient improves, they move out to earn their wages to run the family with the unavoidable default from the treatment

Evaluation of IPM modules for the management of fruit borer and fruit rot diseases in tomato, Lycopersicon esculentum Miller

Among, five IPM modules tested against tomato fruit borer and fruit rot on tomato, the IPM module (M3) consisting of use of pheromone traps (@ 12 traps/ha) just after transplanting the tomato crop , Lycopersicon esculentum Miller for monitoring the population of Helicoverpa armigera . followed by three foliar sprays commencing with a mixture of lamba-cyhalothrin 5EC @ 0.8ml/L(0.04%) and Dithane Z-78 (Zineb) @ 2.5g/L (0.25%) after 10 days of appearance of moths in the traps (after 30 days of transplanting) followed by spray with a mixture of Helicide (Ha NPV) 100 LE @ 0.5ml/L+ Indofil M-45 @ 2.5g/L (0.25%) + Gur (0.05%) + Tween 80 (0.05%) after 15 days of first spray followed by spray with a mixture of lamba-cyhalothrin 5EC @ 0.8ml/L(0.04%) and moximate (cymoxanil + mancozeb) @ 0.25% after 15 days of the second spray was found to be most effective in minimizing the infestation of fruit borer and fruit rot diseases with 50.00% and 63.45% reduction over control, respectively. This module was also found to be most economic resulting in highest marketable fruit yield (255.94q/ha) and maximum net returns (Rs.10.36) per rupee spent. The present findings are of immense utility as there will be reduction in number of sprays resulting in the cost of production of tomato crop

RNA interference: A novel tool for plant disease management

Plant diseases pose a huge threat to crop production globally. Variations in their genomes cause selection to favor those who can survive pesticides and Bacillus thuringiensis (Bt) crops. Though plant breeding has been the classical means of manipulating the plant genome to develop resistant cultivar for controlling plant diseases, the advent of genetic engineering provides an entirely new approach being pursued to render plants resistant to fungi, bacteria, viruses and nematodes. RNA interference (RNAi) technology has emerged to be a promising therapeutic weapon to mitigate the inherent risks such as the use of a specific transgene, marker gene, or gene control sequences associated with development of traditional transgenics. Silencing specific genes by RNAi is a desirable natural solution to this problem as disease resistant transgenic plants can be produced within a regulatory framework. Recent studies have been successful in producing potent silencing effects by using target doublestranded RNAs through an effective vector system. Transgenic plants expressing RNAi vectors, as well as, dsRNA containing crop sprays have been successful for efficient control of plant pathogens affecting economically important crop species. The present paper discusses strategies and applications of this novel technology in plant disease management for sustainable agriculture production.Keywords: Plant disease, RNA interference, transgene, managementAfrican Journal of Biotechnology Vol. 12(18), pp. 2303-231

Microstructural evolution under low shear rates during Rheo processing of LM25 alloy

© ASM InternationalMicrostructural features of LM25 alloy processed by two different routes: (1) conventional casting, and(2)shear casting based on inclined heated surface are studied. The microstructures of the primary phase for the shear-cast samples show rosette or ellipsoidal morphologies. Heat transfer of contacting melt with the inclined tube surface and shear stress exerted on the layers of the melt as result of gravitational force are crucial parameters for the microstructural evolution. Compared to those produced by conventional casting, shear-cast samples have a much improved tensile strength and ductility due to globular microstructure

Molecular Detection of Carbapenem Resistance in Clinical Isolates of Klebsiella pneumoniae in Tertiary Care Hospital

Antibiotic resistance has become a serious global threat, mainly due to misuse, overuse of antibiotics and non-compliance with infection control protocol. Superbugs are multidrug-resistant (MDR) and extended drug-resistant (XDR) bacteria, mainly Klebsiella pneumoniae and Escherichia coli from the Enterobacteriaceae family, which cause opportunistic infections and raise death rates and hospital expenditures. The present study was conducted at a tertiary care teaching hospital to study the epidemiology and molecular detection of carbapenem-resistant K. pneumoniae isolated from various clinical specimens. 240 K. pneumoniae isolates were collected from January 2020 to December 2021 at the Bacteriology laboratory, Index Medical College and Hospital, Indore. All isolates were analyzed for carbapenem resistance by the conventional disc diffusion method. All carbapenem-resistant isolates were tested for carbapenemase production using the phenotypic double-disk synergy test (DDST) and modified Hodge test (MHT) as per 2020 CLSI guidelines. All isolates were negative by phenotypic methods, further confirmed by conventional PCR to detect the gene responsible for carbapenemase production. 240 isolates of K. pneumoniae were included during the study periods. Out of 240 isolates, 102 isolates were found resistant to carbapenem drugs. All 102 isolates were confirmed carbapenemase and MBL producers by MHT and DDST tests. Among 102, 60 isolates were found to be MBL producers negative by MHT and DDST tests. Sixty phenotypic negative carbapenem-resistant isolates were tested by conventional PCR. One or more carbapenemase genes were detected in 61.0% of isolates. The blaKPC was detected in 13/60 (21%) isolates, followed by blaNDM 10/60 (16%) isolates, followed by blaVIM in 6/60(10%), blaOXA-48 in 5/60 (8%) and blaIMP in 3/60(5%) isolates. K. pneumoniae produces carbapenemase, which enhances resistance to the carbapenem class of antibiotics. The simultaneous detection of these resistance genes expressed by Klebsiella pneumoniae might be managed by early detection and adhering to antibiotic policies that limit the use of antibiotics