The RCB star V854 Cen is surrounded by a hot dusty shell

Aims : The hydrogen-deficient supergiants known as R Coronae Borealis (RCB) stars might be the result of a double-degenerate merger of two white dwarfs (WDs), or a final helium shell flash in a planetary nebula central star. In this context, any information on the geometry of their circumstellar environment and, in particular, the potential detection of elongated structures, is of great importance. Methods : We obtained near-IR observations of V854 Cen with the AMBER recombiner located at the Very Large Telescope Interferometer (VLTI) array with the compact array (B$\leq$35m) in 2013 and the long array (B$\leq$140m) in 2014. At each time, V854 Cen was at maximum light. The $H$- and $K$-band continua were investigated by means of spectrally dependant geometric models. These data were supplemented with mid-IR VISIR/VLT images. Results : A dusty slightly elongated over density is discovered both in the $H$- and $K$-band images. With the compact array, the central star is unresolved ($\Theta\leq2.5$\,mas), but a flattened dusty environment of $8 \times 11$ mas is discovered whose flux increases from about $\sim$20% in the $H$ band to reach about $\sim$50% at 2.3\micron, which indicates hot (T$\sim$1500\,K) dust in the close vicinity of the star. The major axis is oriented at a position angle (P.A.) of 126$\pm$29$\deg$. Adding the long-array configuration dataset provides tighter constraints on the star diameter ($\Theta\leq1.0$ mas), a slight increase of the overdensity to $12 \times 15$ mas and a consistent P.A. of 133$\pm$49$\deg$. The closure phases, sensitive to asymmetries, are null and compatible with a centro-symmetric, unperturbed environment excluding point sources at the level of 3% of the total flux in 2013 and 2014. The VISIR images exhibit a flattened aspect ratio at the 15-20% level at larger distances ($\sim$1\arcsec) with a position angle of 92$\pm$19$\deg$, marginally consistent with the interferometric observations. Conclusions : This is the first time that a moderately elongated structure has been observed around an RCB star. These observations confirm the numerous suggestions for a bipolar structure proposed for this star in the literature, which were mainly based on polarimetric and spectroscopic observations.Comment: Accepted by A\&A, new version after language editing, Astronomy and Astrophysics (2014

Effective Hamiltonian Approach to Hyperon Beta Decay with Final-State Baryon Polarization

Using an effective Hamiltonian approach, we obtain expressions for hyperon beta decay final-state baryon polarization. Terms through second order in the energy release are retained. The resulting approximate expressions are much simpler and more compact than the exact expressions, and they agree closely with them.Comment: 1 Figure Will appear in Phys Rev D 60 Article 117505 (Dec 1, 1999

Total column CO_2 measurements at Darwin, Australia – site description and calibration against in situ aircraft profiles

An automated Fourier Transform Spectroscopic (FTS) solar observatory was established in Darwin, Australia in August 2005. The laboratory is part of the Total Carbon Column Observing Network, and measures atmospheric column abundances of CO_2 and O_2 and other gases. Measured CO_2 columns were calibrated against integrated aircraft profiles obtained during the TWP-ICE campaign in January–February 2006, and show good agreement with calibrations for a similar instrument in Park Falls, Wisconsin. A clear-sky low airmass relative precision of 0.1% is demonstrated in the CO2 and O2 retrieved column-averaged volume mixing ratios. The 1% negative bias in the FTS X_(CO_2) relative to the World Meteorological Organization (WMO) calibrated in situ scale is within the uncertainties of the NIR spectroscopy and analysis

Engineered carbon-nanomaterial-based electrochemical sensors for biomolecules

The study of electrochemical behavior of bioactive molecules has become one of the most rapidly developing scientific fields. Biotechnology and biomedical engineering fields have a vested interest in constructing more precise and accurate voltammetric/amperometric biosensors. One rapidly growing area of biosensor design involves incorporation of carbon-based nanomaterials in working electrodes, such as one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide. In this review article, we give a brief overview describing the voltammetric techniques and how these techniques are applied in biosensing, as well as the details surrounding important biosensing concepts of sensitivity and limits of detection. Building on these important concepts, we show how the sensitivity and limit of detection can be tuned by including carbon-based nanomaterials in the fabrication of biosensors. The sensing of biomolecules including glucose, dopamine, proteins, enzymes, uric acid, DNA, RNA, and H2O2 traditionally employs enzymes in detection; however, these enzymes denature easily, and as such, enzymeless methods are highly desired. Here we draw an important distinction between enzymeless and enzyme-containing carbon-nanomaterial-based biosensors. The review ends with an outlook of future concepts that can be employed in biosensor fabrication, as well as limitations of already proposed materials and how such sensing can be enhanced. As such, this review can act as a roadmap to guide researchers toward concepts that can be employed in the design of next generation biosensors, while also highlighting the current advancements in the field.ope

Dust around red supergiants in the Magellanic Clouds

It is both surprising and exciting to find that young galaxies at high redshift contain large dust masses. For galaxies at z \u3e 5, after only 1 Gyr, there has not been time for low-mass stars to have evolved to the AGB phase and produce dust. In such galaxies, Type II SNe and red supergiants (RSGs) may even dominate the dust production rate. It has long been known that RSG atmospheres produce dust, but little is known about it. We are pursuing three parallel studies to better understand RSG dust. First, we are using optical spectra and JHK photometry to characterize the optical and near-IR extinction curves of the RSGs. Second, we are using the optical spectra combined with 2MASS, IRAC and MIPS photometry to estimate the dust mass loss rates from Local Group RSGs. In addition, we will use our Monte Carlo radiative transfer models to analyze the emission from dust in the circumstellar shells. Third, the final piece of the puzzle is being provided by obtaining new IRS spectra of LMC and SMC RSGs. We plan to use the IRS to make a systematic study of the dust properties in RSG shells in the LMC and SMC so that we can probe how they may vary with a large range of galactic metallicities. The derived stellar SEDs and extinction curves will be combined with Spitzer IRAC and MIPS photometry and IRS spectra for use as inputs to our Monte Carlo codes which will be used to study the composition, size distributions and clumpiness of the dust. © 2009 International Astronomical Union

The working alliance in stuttering treatment: a neglected variable?

Background Multiple factors can influence the working alliance and treatment outcome in speech and language therapy. The ‘working alliance’ is an important concept in treatment and can be described as the degree to which a treatment dyad is engaged in collaborative, purposive work. To date, relatively little attention has been paid to this concept within speech and language treatment in general, and within stuttering treatment research in particular. Aims To investigate the role of the working alliance within stuttering treatment, and to evaluate whether the quality of the working alliance correlated with clients’ concept of motivation and treatment outcomes 6 months post‐therapy. Methods & Procedures Eighteen adults (21‐61 years) participated in this multiple single‐case treatment study, with treatment facilitated by an experienced speech and language therapist. The working alliance was investigated using the Working Alliance Inventory—Short Version Revised (WAI‐SR), an Extended version of the Client Preferences for Stuttering Treatment (CPST‐E), the Overall Assessment of Speakers’ Experience of Stuttering—Adult version (OASES‐A), the Wright & Ayre Stuttering Self‐Rating Profile (WASSP) and the Hospital Anxiety and Depression Scale (HADS). Outcomes & Results Analyses demonstrated significant associations between the working alliance and client motivation (r = 0.781) and treatment outcomes (r = 0.644) 6 months post‐treatment. The association between client‐led goals and therapy tasks appeared particularly important. Conclusions & Implications The working alliance between speech and language therapists and persons who stutter matters. Within the alliance, the level of client–clinician agreement on treatment goals and therapy tasks may be of greater importance than the bond between client and clinician. Further research with greater numbers of participants is warranted

Identification of pathogen genomic variants through an integrated pipeline

Background: Whole-genome sequencing represents a powerful experimental tool for pathogen research. We present methods for the analysis of small eukaryotic genomes, including a streamlined system (called Platypus) for finding single nucleotide and copy number variants as well as recombination events. Results: We have validated our pipeline using four sets of Plasmodium falciparum drug resistant data containing 26 clones from 3D7 and Dd2 background strains, identifying an average of 11 single nucleotide variants per clone. We also identify 8 copy number variants with contributions to resistance, and report for the first time that all analyzed amplification events are in tandem. Conclusions: The Platypus pipeline provides malaria researchers with a powerful tool to analyze short read sequencing data. It provides an accurate way to detect SNVs using known software packages, and a novel methodology for detection of CNVs, though it does not currently support detection of small indels. We have validated that the pipeline detects known SNVs in a variety of samples while filtering out spurious data. We bundle the methods into a freely available package

A designer's approach: How can autistic adults with learning disabilities be involved in the design process?

Autistic adults with limited speech and additional learning disabilities who are often excluded from design research are at the heart of this project. These are people whose perceptions, experiences and interactions with their surroundings are unique, but also are people who may not be able to communicate verbally their differences to the remaining 99% of the population. This, in combination with their distinctive cognitive profile, has resulted in a lack of studies involving people living with autism, and consequently their life experiences may neither be heard nor understood and remain largely unexplored. By reflecting upon the ongoing design collaboration between The Helen Hamlyn Centre for Design and the autism charity The Kingwood Trust, this paper reflects on the approach and methods used in three design studies. Particular attention is paid towards the careful selection, adaptation and development of collaborative design methods for autistic adults and their support staff to be involved. By working beyond the boundaries of a neurotypical culture, the project aims to support the greater goal of improving the everyday experiences of people living with autism by breaking down the barriers to participation