Prosthesis coupling

A coupling for use in an apparatus for connecting a prosthesis to the bone of a stump of an amputated limb is described which permits a bio-compatible carbon sleeve forming a part of the prosthesis connector to float so as to prevent disturbing the skin seal around the carbon sleeve. The coupling includes a flexible member interposed between a socket that is inserted within an intermedullary cavity of the bone and the sleeve. A lock pin is carried by the prosthesis and has a stem portion which is adapted to be coaxially disposed and slideably within the tubular female socket for securing the prosthesis to the stump. The skin around the percutaneous carbon sleeve is able to move as a result of the flexing coupling so as to reduce stresses caused by changes in the stump shape and/or movement between the bone and the flesh portion of the stump

Analysis of surface tris (2,3-dibromopropyl) phosphate on chlorobutyl rubber SCAPE suits

Tris (2,30-dibromopropyl) phosphate was used to confer flame retardant properties on butyl rubber formulations used in protective clothing such as the self-contained atmospheric protective ensembles (SCAPE suits) worn at Kennedy Space Center in support of Apollo, Skylab, and Apollo-Soyuz missions since 1966. Because tris (2,3-dibromopropyl) phosphate is mutagenic, surface concentrations of the compound in SCAPE suits were investigated as were as potential methods of removing or isolating it. Analytical procedures for determining surface concentrations of the tris compound on non-porous materials are described. Soap-and-water washing is the most efficient method of removing the compound from fabricated SCAPE suits and unused material

Development of a public audiology service in Southern Malawi: profile of patients across two years

Objective To describe the profile of patients attending the Queen Elizabeth Central Hospital (QECH) audiology clinic in Malawi, over a two-year period (2016–2017). Design A retrospective patient record review. Study sample There were 2299 patients assessed at the QECH audiology department between January 2016 and December 2017. Adult patients’ ages ranged from 18 to 94 years (M = 45.8, SD = 19.22). The mean age of children included in this study was 7.7 years (SD= 5.21). Overall, 45.4% of patients were female. Results Of the 61.6% of adults and 41.7% of children found to have some degree of hearing loss, 28.3% and 15.4% were fitted with hearing aids, respectively. The number of patients seen in 2017 (n = 1385) was 34% higher than that of 2016 (n = 914). Conclusion This study found that demand for hearing services is increasing in this public sector Malawian audiology department but uptake of hearing aids for those in need is low. Future evaluation of service provision and treatment outcomes is needed. Results from this study can be used to inform the development of future audiology clinics in low resource settings

Effective Hamiltonian Approach to Hyperon Beta Decay with Final-State Baryon Polarization

Using an effective Hamiltonian approach, we obtain expressions for hyperon beta decay final-state baryon polarization. Terms through second order in the energy release are retained. The resulting approximate expressions are much simpler and more compact than the exact expressions, and they agree closely with them.Comment: 1 Figure Will appear in Phys Rev D 60 Article 117505 (Dec 1, 1999

Total column CO_2 measurements at Darwin, Australia – site description and calibration against in situ aircraft profiles

An automated Fourier Transform Spectroscopic (FTS) solar observatory was established in Darwin, Australia in August 2005. The laboratory is part of the Total Carbon Column Observing Network, and measures atmospheric column abundances of CO_2 and O_2 and other gases. Measured CO_2 columns were calibrated against integrated aircraft profiles obtained during the TWP-ICE campaign in January–February 2006, and show good agreement with calibrations for a similar instrument in Park Falls, Wisconsin. A clear-sky low airmass relative precision of 0.1% is demonstrated in the CO2 and O2 retrieved column-averaged volume mixing ratios. The 1% negative bias in the FTS X_(CO_2) relative to the World Meteorological Organization (WMO) calibrated in situ scale is within the uncertainties of the NIR spectroscopy and analysis

Dust around red supergiants in the Magellanic Clouds

It is both surprising and exciting to find that young galaxies at high redshift contain large dust masses. For galaxies at z \u3e 5, after only 1 Gyr, there has not been time for low-mass stars to have evolved to the AGB phase and produce dust. In such galaxies, Type II SNe and red supergiants (RSGs) may even dominate the dust production rate. It has long been known that RSG atmospheres produce dust, but little is known about it. We are pursuing three parallel studies to better understand RSG dust. First, we are using optical spectra and JHK photometry to characterize the optical and near-IR extinction curves of the RSGs. Second, we are using the optical spectra combined with 2MASS, IRAC and MIPS photometry to estimate the dust mass loss rates from Local Group RSGs. In addition, we will use our Monte Carlo radiative transfer models to analyze the emission from dust in the circumstellar shells. Third, the final piece of the puzzle is being provided by obtaining new IRS spectra of LMC and SMC RSGs. We plan to use the IRS to make a systematic study of the dust properties in RSG shells in the LMC and SMC so that we can probe how they may vary with a large range of galactic metallicities. The derived stellar SEDs and extinction curves will be combined with Spitzer IRAC and MIPS photometry and IRS spectra for use as inputs to our Monte Carlo codes which will be used to study the composition, size distributions and clumpiness of the dust. © 2009 International Astronomical Union

Spectroscopic Characteristics of Carbon Dots (C-Dots) Derived from Carbon Fibers and Conversion to Sulfur-Bridged C-Dots Nanosheets

We synthesized sub‐10 nm carbon nanoparticles (CNPs) consistent with photoluminescent carbon dots (C-dots) from carbon fiber starting material. The production of different C-dots fractions was monitored over seven days. During the course of the reaction, one fraction of C-dots species with relatively high photoluminescence was short-lived, emerging during the first hour of reaction but disappearing after one day of reaction. Isolation of this species during the first hour of the reaction was crucial to obtaining higher-luminescent C-dots species. When the reaction proceeded for one week, the appearance of larger nanostructures was observed over time, with lateral dimensions approaching 200 nm. The experimental evidence suggests that these larger species are formed from small C-dot nanoparticles bridged together by sulfur-based moieties between the C-dot edge groups, as if the C-dots polymerized by cross-linking the edge groups through sulfur bridges. Their size can be tailored by controlling the reaction time. Our results highlight the variety of CNP products, from sub‐10 nm C-dots to ~200 nm sulfur-containing carbon nanostructures, that can be produced over time during the oxidation reaction of the graphenic starting material. Our work provides a clear understanding of when to stop the oxidation reaction during the top-down production of C-dots to obtain highly photoluminescent species or a target average particle size

A designer's approach: How can autistic adults with learning disabilities be involved in the design process?

Autistic adults with limited speech and additional learning disabilities who are often excluded from design research are at the heart of this project. These are people whose perceptions, experiences and interactions with their surroundings are unique, but also are people who may not be able to communicate verbally their differences to the remaining 99% of the population. This, in combination with their distinctive cognitive profile, has resulted in a lack of studies involving people living with autism, and consequently their life experiences may neither be heard nor understood and remain largely unexplored. By reflecting upon the ongoing design collaboration between The Helen Hamlyn Centre for Design and the autism charity The Kingwood Trust, this paper reflects on the approach and methods used in three design studies. Particular attention is paid towards the careful selection, adaptation and development of collaborative design methods for autistic adults and their support staff to be involved. By working beyond the boundaries of a neurotypical culture, the project aims to support the greater goal of improving the everyday experiences of people living with autism by breaking down the barriers to participation

The working alliance in stuttering treatment: a neglected variable?

Background Multiple factors can influence the working alliance and treatment outcome in speech and language therapy. The ‘working alliance’ is an important concept in treatment and can be described as the degree to which a treatment dyad is engaged in collaborative, purposive work. To date, relatively little attention has been paid to this concept within speech and language treatment in general, and within stuttering treatment research in particular. Aims To investigate the role of the working alliance within stuttering treatment, and to evaluate whether the quality of the working alliance correlated with clients’ concept of motivation and treatment outcomes 6 months post‐therapy. Methods & Procedures Eighteen adults (21‐61 years) participated in this multiple single‐case treatment study, with treatment facilitated by an experienced speech and language therapist. The working alliance was investigated using the Working Alliance Inventory—Short Version Revised (WAI‐SR), an Extended version of the Client Preferences for Stuttering Treatment (CPST‐E), the Overall Assessment of Speakers’ Experience of Stuttering—Adult version (OASES‐A), the Wright & Ayre Stuttering Self‐Rating Profile (WASSP) and the Hospital Anxiety and Depression Scale (HADS). Outcomes & Results Analyses demonstrated significant associations between the working alliance and client motivation (r = 0.781) and treatment outcomes (r = 0.644) 6 months post‐treatment. The association between client‐led goals and therapy tasks appeared particularly important. Conclusions & Implications The working alliance between speech and language therapists and persons who stutter matters. Within the alliance, the level of client–clinician agreement on treatment goals and therapy tasks may be of greater importance than the bond between client and clinician. Further research with greater numbers of participants is warranted

Engineered carbon-nanomaterial-based electrochemical sensors for biomolecules

The study of electrochemical behavior of bioactive molecules has become one of the most rapidly developing scientific fields. Biotechnology and biomedical engineering fields have a vested interest in constructing more precise and accurate voltammetric/amperometric biosensors. One rapidly growing area of biosensor design involves incorporation of carbon-based nanomaterials in working electrodes, such as one-dimensional carbon nanotubes, two-dimensional graphene, and graphene oxide. In this review article, we give a brief overview describing the voltammetric techniques and how these techniques are applied in biosensing, as well as the details surrounding important biosensing concepts of sensitivity and limits of detection. Building on these important concepts, we show how the sensitivity and limit of detection can be tuned by including carbon-based nanomaterials in the fabrication of biosensors. The sensing of biomolecules including glucose, dopamine, proteins, enzymes, uric acid, DNA, RNA, and H2O2 traditionally employs enzymes in detection; however, these enzymes denature easily, and as such, enzymeless methods are highly desired. Here we draw an important distinction between enzymeless and enzyme-containing carbon-nanomaterial-based biosensors. The review ends with an outlook of future concepts that can be employed in biosensor fabrication, as well as limitations of already proposed materials and how such sensing can be enhanced. As such, this review can act as a roadmap to guide researchers toward concepts that can be employed in the design of next generation biosensors, while also highlighting the current advancements in the field.ope