Priorato de la Anunciación

«Desde lejos se divisará el campanario, marcando su silueta enérgica y distintiva en el árido paisaje, y desde cerca su presencia señalará la aproximación a la Capilla. Las campanas de bronce indicarán las horas en que harán los Oficios diarios. Su forma airosa y aristada se presta fácilmente a la técnica del hormigón armado y sus encofrados»

Edificio Van Leer. Holanda

This building houses the offices of a large industrial firm. The central part of the building is H shaped and has two floor. The general services, washrooms, dressing rooms, stores, archive and mechanical equipment are housed on the ground floor. This level also provides communication between the offices in the wings and the staff canteen. The top floor has a hall-cum-reception room, the exhibition of the firms products and a section of the offices. The two lateral wings, which are Y shaped in planform, are taken up with offices on both floor levels. This building clearly shows the touch of a master designer in its layout, finish and details. It is a most perfect solution in terms of its location, its function and its human requirements.El complejo aloja las oficinas de una gran empresa industrial. El cuerpo central del edificio principal—en forma de H—tiene dos plantas: la baja comprende los servicios generales, aseos y vestuarios para empleados, almacenes, archivo, equipos mecánicos, etc., y sirve de calle y comunicación entre los niveles inferiores de las alas de oficinas y la cantina para empleados. La planta alta alberga el vestíbulo, utilizado también como sala de recepción, espera, exposición de los productos fabricados por las factorías de la empresa y parte de oficinas. Las dos alas laterales—con plantas en forma de V—alojan, en sus dos niveles, las oficinas generales. El planteamiento, acabado y detalles de este inmueble muestran la mano de un maestro, que ha realizado un trabajo perfecto, teniendo en cuenta el emplazamiento—Holanda—, el lugar y el cometido a que se destina el edificio

Modelling of Energy-Crops in Agricultural Sector Models - A Review of Existing Methodologies

The present report provides an overview of the different methodologies applied in partial and general equilibrium models used to analyse biofuel policies in Europe, as well as their methodological pros and cons. While the LEITAP model is included as a general equilibrium model covering biofuel demand, partial equilibrium models are represented by ESIM, FAPRI, AGLINK/COSIMO, RAUMIS, AGMEMOD (agricultural models); POLES and PRIMES (energy sector); and EUFASOM/ENFA (forestry sector). The study is highly relevant for the current modelling work at IPTS, where models such as ESIM and AGLINK play an important role in the Integrated Modelling Platform for Agro-economic Commodity and Policy Analysis (iMAP) of the AGRILIFE Unit. Additionally, the POLES model is currently part of the model portfolio used by the Competitiveness & Sustainability Unit in several studies analysing possible technological pathways of energy production and demand for bioenergy in Europe, a result of implementing the biofuel directive. This compilation of information is also important since the implicit and explicit treatment of bioenergy, either as a demand shock to the processing of oilseeds or feedstock for bioethanol and biodiesel, or as the introduction of a biofuel-sector into a computational general equilibrium (CGE) is foreseen in the short-term by other economic models used at IPTS.JRC.J.5-Agriculture and Life Sciences in the Econom

Fiber Coupled Transceiver with 6.5 THz Bandwidth for Terahertz Time-Domain Spectroscopy in Reflection Geometry

We present a fiber coupled transceiver head for terahertz (THz) time-domain reflection measurements. The monolithically integrated transceiver chip is based on iron (Fe) doped In0.53Ga0.47As (InGaAs:Fe) grown by molecular beam epitaxy. Due to its ultrashort electron lifetime and high mobility, InGaAs:Fe is very well suited as both THz emitter and receiver. A record THz bandwidth of 6.5 THz and a peak dynamic range of up to 75 dB are achieved. In addition, we present THz imaging in reflection geometry with a spatial resolution as good as 130 µm. Hence, this THz transceiver is a promising device for industrial THz sensing applications

GRBAlpha: the smallest astrophysical space observatory -- Part 1: Detector design, system description and satellite operations

Aims. Since launched on 2021 March 22, the 1U-sized CubeSat GRBAlpha operates and collects scientific data on high-energy transients, making it the smallest astrophysical space observatory to date. GRBAlpha is an in-obit demonstration of a gamma-ray burst (GRB) detector concept suitably small to fit into a standard 1U volume. As it was demonstrated in a companion paper, GRBAlpha adds significant value to the scientific community with accurate characterization of bright GRBs, including the recent outstanding event of GRB 221009A. Methods. The GRB detector is a 75x75x5 mm CsI(Tl) scintillator wrapped in a reflective foil (ESR) read out by an array of SiPM detectors, multi-pixel photon counters by Hamamatsu, driven by two separate, redundant units. To further protect the scintillator block from sunlight and protect the SiPM detectors from particle radiation, we apply a multi-layer structure of Tedlar wrapping, anodized aluminium casing and a lead-alloy shielding on one edge of the assembly. The setup allows observations of gamma radiation within the energy range of 70-890 keV with an energy resolution of ~30%. Results. Here, we summarize the system design of the GRBAlpha mission, including the electronics and software components of the detector, some aspects of the platform as well as the current way of semi-autonomous operations. In addition, details are given about the raw data products and telemetry in order to encourage the community for expansion of the receiver network for our initiatives with GRBAlpha and related experiments.Comment: Accepted for publication in Astronomy & Astrophysics, 9 pages, 10 figure

The peak-flux of GRB 221009A measured with GRBAlpha

The brightest gamma-ray burst ever observed, long-duration GRB 221009A, was detected by GRBAlpha nano-satellite without saturation. We present light curves of the prompt emission in 13 energy bands, from 80 keV to 950 keV, and perform a spectral analysis to calculate the peak flux and peak isotropic-equivalent luminosity. Since the satellite's attitude information is not available for the time of this GRB, more than 200 incident directions were probed in order to find the median luminosity and its systematic uncertainty. We found that the peak flux in the $80-800$ keV range (observer frame) was $F_{\rm{ph}}^{\rm{p}}=1300_{-200}^{+1200}$ ph cm$^{-2}$s$^{-1}$ or $F_{\rm{erg}}^{\rm{p}}=5.7_{-0.7}^{+3.7}\times10^{-4}$ erg cm$^{-2}$s$^{-1}$ and the fluence in the same energy range of the first GRB episode lasting 300 s, which was observable by GRBAlpha, was $S=2.2_{-0.3}^{+1.4}\times10^{-2}$ erg cm$^{-2}$ or $S^{\rm{bol}}=4.9_{-0.5}^{+0.8}\times10^{-2}$ erg cm$^{-2}$ for the extrapolated range of $0.9-8,690$ keV. We infer the isotropic-equivalent released energy of the first GRB episode to be $E_{\rm{iso}}^{\rm{bol}}=2.8_{-0.5}^{+0.8}\times10^{54}$ erg in the $1-10,000$ keV band (rest frame at $z=0.15$). The peak isotropic-equivalent luminosity in the $92-920$ keV range (rest frame) was $L_{\rm{iso}}^{\rm{p}}=3.7_{-0.5}^{+2.5}\times10^{52}$ erg s$^{-1}$ and the bolometric peak isotropic-equivalent luminosity was $L_{\rm{iso}}^{\rm{p,bol}}=8.4_{-1.5}^{+2.5}\times10^{52}$ erg s$^{-1}$ (4 s scale) in the $1-10,000$ keV range (rest frame). The peak emitted energy is $E_p^\ast=E_p(1+z)=1120\pm470$ keV. Our measurement of $L_{\rm{iso}}^{\rm{p,bol}}$ is consistent with the Yonetoku relation. It is possible that, due to the spectral evolution of this GRB and orientation of GRBAlpha at the peak time, the true values of peak flux, fluence, $L_{\rm{iso}}$, and $E_{\rm{iso}}$ are even higher. [abridged]Comment: 7 pages, 7 figures, 1 table, accepted for publication in Astronomy & Astrophysic

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I:Wet lab procedure

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen detection technique for determination of the DNA/RNA sequences in a variety of sample types and infectious syndromes. mHTS is still in its early stages of translating into clinical application. To support the development, implementation and standardization of mHTS procedures for virus diagnostics, the European Society for Clinical Virology (ESCV) Network on Next-Generation Sequencing (ENNGS) has been established. The aim of ENNGS is to bring together professionals involved in mHTS for viral diagnostics to share methodologies and experiences, and to develop application recommendations. This manuscript aims to provide practical recommendations for the wet lab procedures necessary for implementation of mHTS for virus diagnostics and to give recommendations for development and validation of laboratory methods, including mHTS quality assurance, control and quality assessment protocols

Crowdsourcing hypothesis tests: Making transparent how design choices shape research results

To what extent are research results influenced by subjective decisions that scientists make as they design studies? Fifteen research teams independently designed studies to answer fiveoriginal research questions related to moral judgments, negotiations, and implicit cognition. Participants from two separate large samples (total N > 15,000) were then randomly assigned to complete one version of each study. Effect sizes varied dramatically across different sets of materials designed to test the same hypothesis: materials from different teams renderedstatistically significant effects in opposite directions for four out of five hypotheses, with the narrowest range in estimates being d = -0.37 to +0.26. Meta-analysis and a Bayesian perspective on the results revealed overall support for two hypotheses, and a lack of support for three hypotheses. Overall, practically none of the variability in effect sizes was attributable to the skill of the research team in designing materials, while considerable variability was attributable to the hypothesis being tested. In a forecasting survey, predictions of other scientists were significantly correlated with study results, both across and within hypotheses. Crowdsourced testing of research hypotheses helps reveal the true consistency of empirical support for a scientific claim.</div

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen detection technique for determination of the DNA/RNA sequences in a variety of sample types and infectious syndromes. mHTS is still in its early stages of translating into clinical application. To support the development, implementation and standardization of mHTS procedures for virus diagnostics, the European Society for Clinical Virology (ESCV) Network on Next-Generation Sequencing (ENNGS) has been established. The aim of ENNGS is to bring together professionals involved in mHTS for viral diagnostics to share methodologies and experiences, and to develop application recommendations. This manuscript aims to provide practical recommendations for the wet lab procedures necessary for implementation of mHTS for virus diagnostics and to give recommendations for development and validation of laboratory methods, including mHTS quality assurance, control and quality assessment protocols

Recommendations for the introduction of metagenomic high-throughput sequencing in clinical virology, part I: Wet lab procedure

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen detection technique for determination of the DNA/RNA sequences in a variety of sample types and infectious syndromes. mHTS is still in its early stages of translating into clinical application. To support the development, implementation and standardization of mHTS procedures for virus diagnostics, the European Society for Clinical Virology (ESCV) Network on Next-Generation Sequencing (ENNGS) has been established. The aim of ENNGS is to bring together professionals involved in mHTS for viral diagnostics to share methodologies and experiences, and to develop application recommendations. This manuscript aims to provide practical recommendations for the wet lab procedures necessary for i