17,517 research outputs found

    Collide and Conquer: Constraints on Simplified Dark Matter Models using Mono-X Collider Searches

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    The use of simplified models as a tool for interpreting dark matter collider searches has become increasingly prevalent, and while early Run II results are beginning to appear, we look to see what further information can be extracted from the Run I dataset. We consider three `standard' simplified models that couple quarks to fermionic singlet dark matter: an ss-channel vector mediator with vector or axial-vector couplings, and a tt-channel scalar mediator. Upper limits on the couplings are calculated and compared across three alternate channels, namely mono-jet, mono-ZZ (leptonic) and mono-W/ZW/Z (hadronic). The strongest limits are observed in the mono-jet channel, however the computational simplicity and absence of significant tt-channel model width effects in the mono-boson channels make these a straightforward and competitive alternative. We also include a comparison with relic density and direct detection constraints.Comment: 32 pages, 8 figures; v2: minor changes, conclusion unchanged, matches published versio

    A Genome Sequence of Oceanimonas doudoroffii ATCC 27123T

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    Oceanimonas doudoroffii ATCC 27123T is an obligately aerobic Gram-negative rod of the class Gammaproteobacteria. It was first isolated from surface seawater off the coast of Oahu, HI, USA, in 1972. The predicted genome size is 3,832,938 bp (G+C content, 60.03%), which contains 3,524 predicted coding sequences

    Draft Genome Sequence of the Marine Bacterium Oceanimonas baumannii ATCC 700832T

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    The aerobic phenol-degrading Gram-negative rod Oceanimonas baumannii ATCC 700832T was first isolated from estuary mud from the River Wear, United Kingdom, in 1983. Information on the draft genome sequence for O. baumannii ATCC 700832T is included in this announcement. The predicted genome size is 3,809,332 bp, with 55.88% G+C content

    Diagnostic services in Australia: service rates and characteristics of patients

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    Background: Diagnostic services are the most common area of dental service in Australia. The objective was to investigate differences in services per visit for examinations and radiographs in relation to the characteristics of patients receiving these services in terms of age and sex, aspects of visiting such as dental insurance and reasons for visit, and oral health such as number of teeth and presence of decay. Methods: A random sample of Australian dentists was surveyed in 2009-10. Data on diagnostic services and patient characteristics were collected from a service log. Results: A total of 1,148 dentists responded (response rate=67%). Models adjusted for age and gender of patients showed that rates [Rate Ratio, 95% CI] of examinations were higher for insured patients [1.13; 1.06-1.21], while rates of radiographs were higher for emergency visits [1.25; 1.11-1.48]. Patients with 20 or more teeth had higher rates for examinations [1.15; 1.01- Accepted Article This article is protected by copyright. All rights reserved. 1.32] and radiographs [1.28; 1.02-1.60]. Decayed teeth were associated with lower examination rates [0.70; 0.65-0.76] but higher rates of radiographs [1.34; 1.16-1.55]. Conclusions: The finding that number of teeth was associated with higher rates of examinations and radiographs suggests that retention of teeth could be influencing the increasing rates of diagnostic services in Australia.DS Brennan, M Balasubramanian, AJ Spence

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    Fusing Information in a 3D Chart-of-the-Future Display

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    The Data Visualization Research Lab at the Center for Coastal and Ocean Mapping is investigating how three-dimensional navigational displays can most effectively be constructed. This effort is progressing along multiple paths and is implemented in the GeoNav3D system, a 3D chart-of-the-future research prototype. We present two lines of investigation here. First, we explore how tide, depth, and planning information can be combined (fused) into a single view, in order to give the user a more realistic picture of effective water depths. In the GeoNav3D system, 3D shaded bathymetry, coded for color depth, is used to display navigable areas. As in ENC displays, different colors are used to easily identify areas that are safe, areas where under-keel clearance is minimal, and areas where depths are too shallow. Real-time or model-generated tide information is taken into account in dynamically color-coding the depths. One advantage to using a continuous bathymetric model, versus discrete depth areas, is that the model can be continuously adjusted for water level. This concept is also extended for planning purposes by displaying the color-coded depths along a proposed corridor at the expected time of reaching each point. In our second line of investigation, we explore mechanisms for linking information from multiple 3D views into a coherent whole. In GeoNav3D, it is possible to create a variety of plan and perspective views, and these views can be attached to moving reference frames. This provides not only semi-static views such as from-the-bridge and under-keel along-track profile views, but also more dynamic, interactive views. These views are linked through visual devices that allow the fusion of information from among the views. We present several such devices and show how they highlight relevant details and help to minimize user confusion. Investigation into the utility of various linked views for aiding realsituation decision-making is ongoin

    Sea anemone model has a single Toll-like receptor that can function in pathogen detection, NF-κB signal transduction, and development

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    In organisms from insects to vertebrates, Toll-like receptors (TLRs) are primary pathogen detectors that activate downstream pathways, specifically those that direct expression of innate immune effector genes. TLRs also have roles in development in many species. The sea anemone Nematostella vectensis is a useful cnidarian model to study the origins of TLR signaling because its genome encodes a single TLR and homologs of many downstream signaling components, including the NF-κB pathway. We have characterized the single N. vectensis TLR (Nv-TLR) and demonstrated that it can activate canonical NF-κB signaling in human cells. Furthermore, we show that the intracellular Toll/IL-1 receptor (TIR) domain of Nv-TLR can interact with the human TLR adapter proteins MAL and MYD88. We demonstrate that the coral pathogen Vibrio coralliilyticus causes a rapidly lethal disease in N. vectensis and that heat-inactivated V. coralliilyticus and bacterial flagellin can activate a reconstituted Nv-TLR–to–NF-κB pathway in human cells. By immunostaining of anemones, we show that Nv-TLR is expressed in a subset of cnidocytes and that many of these Nv-TLR–expressing cells also express Nv-NF-κB. Additionally, the nematosome, which is a Nematostella-specific multicellular structure, expresses Nv-TLR and many innate immune pathway homologs and can engulf V. coralliilyticus. Morpholino knockdown indicates that Nv-TLR also has an essential role during early embryonic development. Our characterization of this primitive TLR and identification of a bacterial pathogen for N. vectensis reveal ancient TLR functions and provide a model for studying the molecular basis of cnidarian disease and immunity.IOS-1354935 - National Science Foundation (NSF); GRFP - National Science Foundation (NSF); GRFP - National Science Foundation (NSF); 1262934 - National Science Foundation (NSF); 2014-BSP - Arnold and Mabel Beckman Foundatio

    An Integrated Circuit for Signal Processing of the AMS RICH Photmultipliers Tubes

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    An analog integrated circuit has been designed, in a BiCMOS 0.8 micron technology, for the feasability study of the signal processing of the AMS RICH photomultiplier tubes. This low power, three channel gated integrator includes its own gate and no external analog delay is requiered. It processes PMT pulses over a dynamic range of more than 100. A logic output that indicates whether the analog charge has to be considered is provided. This gated integrator is used with a compact DSP based acquisition system in a 132 channels RICH prototype. The charge calibration of each channel is carried out using a LED. The pedestal measurement is performed on activation of a dedicated input. The noise contribution study of the input RC network and amplifiers is presented.Comment: IEEE symp. on Nucl. Sci. and Med. Imaging, Toront
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