A 450-day light curve of the radio afterglow of GRB 970508: Fireball calorimetry

We report on the results of an extensive monitoring campaign of the radio afterglow of GRB 970508, lasting 450 days after the burst. The spectral and temporal radio behavior indicate that the fireball has undergone a transition to sub-relativistic expansion at t~100 days. This allows us to perform "calorimetry" of the explosion. The derived total energy, ~5\times 10^{50} erg, is well below the ~5\times 10^{51} erg inferred under the assumption of spherical symmetry from gamma-ray and early afterglow observations. A natural consequence of this result, which can also account for deviations at t<100 days from the spherical relativistic fireball model predictions, is that the fireball was initially a wide-angle jet of opening angle ~30 degrees. Our analysis also allows to determine the energy fractions carried by electrons and magnetic field, and the density of ambient medium surrounding the fireball. We find that during the sub-relativistic expansion electrons and magnetic field are close to equipartition, and that the density of the ambient medium is ~1/cm^3. The inferred density rules out the possibility that the fireball expands into a strongly non-uniform medium, as would be expected, e.g., in the case of a massive star progenitor.Comment: 33 pages, including 7 figures, submitted to Ap

The 1.4 GHz light curve of GRB 970508

We report on Westerbork 1.4 GHz radio observations of the radio counterpart to $\gamma$-ray burst GRB~970508, between 0.80 and 138 days after this event. The 1.4 GHz light curve shows a transition from optically thick to thin emission between 39 and 54 days after the event. We derive the slope $p$ of the spectrum of injected electrons ($dN/d\gamma_{e}\propto\gamma_{e}^{-p}$) in two independent ways which yield values very close to $p=2.2$. This is in agreement with a relativistic dynamically near-adiabatic blast wave model whose emission is dominated by synchrotron radiation and in which a significant fraction of the electrons cool fast.Comment: Paper I. Accepted for publication in the Astrophysical Journal Letter

A bioinformatics approach to the development of immunoassays for specified risk material in canned meat products

A bioinformatics approach to developing antibodies to specific proteins has been evaluated for the production of antibodies to heat-processed specified risk tissues from ruminants (brain and eye tissue). The approach involved the identification of proteins specific to ruminant tissues by interrogation of the annotation fields within the Swissprot database. These protein sequences were then interrogated for peptide sequences that were unique to the protein. Peptides were selected that met these criteria as close as possible and that were also theoretically resistant to either pepsin or trypsin. The selected peptides were synthesised and used as immunogens to raise monoclonal antibodies. Antibodies specific for the synthetic peptides were raised to half of the selected peptides. These antibodies have each been incorporated into a competitive enzyme-linked immunosorbent assay (ELISA) and shown to be able to detect the heat-processed parent protein after digestion with either pepsin or trypsin. One antibody, specific for alpha crystallin peptide (from bovine eye tissue), was able to detect the peptide in canned meat products spiked with 10% eye tissue. These results, although preliminary in nature, show that bioinformatics in conjunction with enzyme digestion can be used to develop ELISA for proteins in high-temperature processed foods and demonstrate that the approach is worth further stud

Dynamic PRA: an Overview of New Algorithms to Generate, Analyze and Visualize Data

State of the art PRA methods, i.e. Dynamic PRA (DPRA) methodologies, largely employ system simulator codes to accurately model system dynamics. Typically, these system simulator codes (e.g., RELAP5 ) are coupled with other codes (e.g., ADAPT, RAVEN that monitor and control the simulation. The latter codes, in particular, introduce both deterministic (e.g., system control logic, operating procedures) and stochastic (e.g., component failures, variable uncertainties) elements into the simulation. A typical DPRA analysis is performed by: 1. Sampling values of a set of parameters from the uncertainty space of interest 2. Simulating the system behavior for that specific set of parameter values 3. Analyzing the set of simulation runs 4. Visualizing the correlations between parameter values and simulation outcome Step 1 is typically performed by randomly sampling from a given distribution (i.e., Monte-Carlo) or selecting such parameter values as inputs from the user (i.e., Dynamic Event Tre

ALMA unveils wider environment of distant red protocluster core

We report observations with the Atacama Large Millimetre Array (ALMA) of six submillimetre galaxies (SMGs) within 3 arcmin of the Distant Red Core (DRC) at $z=4.0$, a site of intense cluster-scale star formation, first reported by Oteo et al. (2018). We find new members of DRC in three SMG fields; in two fields, the SMGs are shown to lie along the line of sight towards DRC; one SMG is spurious. Although at first sight this rate of association is consistent with earlier predictions, associations with the bright SMGs are rarer than expected, which suggests caution when interpreting continuum over-densities. We consider the implications of all 14 confirmed DRC components passing simultaneously through an active phase of star formation. In the simplest explanation, we see only the tip of the iceberg in terms of star formation and gas available for future star formation, consistent with our remarkable finding that the majority of newly confirmed DRC galaxies are not the brightest continuum emitters in their immediate vicinity. Thus while ALMA continuum follow-up of SMGs identifies the brightest continuum emitters in each field, it does not necessarily reveal all the gas-rich galaxies. To hunt effectively for protocluster members requires wide and deep spectral-line imaging to uncover any relatively continuum-faint galaxies that are rich in atomic or molecular gas. Searching with short-baseline arrays or single-dish facilities, the true scale of the underlying gas reservoirs may be revealed.Comment: 8 pages, 2 colour figures; MNRAS, in pres

The radio to X-ray spectrum of GRB 970508 on May 21.0 UT

We have reconstructed the spectrum of the afterglow of GRB 970508, on May 21.0 UT (12.1 days after the GRB), on the basis of observations spanning the X-ray to radio range. The low-frequency power law index of the spectrum, $\alpha=0.44\pm0.07$ ($F_\nu\propto\nu^\alpha$), is in agreement with the expected value $\alpha=1/3$ for optically thin synchrotron radiation. The 1.4 GHz emission is self-absorbed. We infer constraints on the break frequecies $\nu_{c}$ and $\nu_{m}$ on May 21.0 UT from a spectral transition from $F_{\nu} \sim \nu^{-0.6}$ to $F_{\nu} \sim \nu^{-1.1}$ in the optical passband around 1.4 days. A model of an adiabatically expanding blast wave, emitting synchrotron radiation, in which a significant fraction of the electrons cool rapidly provides a successful and consistent description of the afterglow observations over nine decades in frequency, ranging in time from trigger until several months later.Comment: Paper II. Accepted for publication in the Astrophysical Journal Letter

Core–shell catalyst pellets for effective reaction heat management

Catalyst research is concerned with synthesizing increasingly active materials, leading to safety issues at reactor scale, unless the reaction heat release is controllable. Computational studies predict that core–shell pellets with catalytically active core and inert shell are beneficial for this purpose, compared to established concepts such as catalyst pellet dilution. At high temperatures, reactant diffusion through the shell becomes rate-determining, resulting in a well-controllable heat release rate, which prevents further temperature increase. Here, industrial catalyst pellets were coated in a fluidized-bed pilot plant, demonstrating large-scale production feasibility. The obtained pellets were characterized via Dynamic Image Analysis, Scanning Electron Microscopy and X-ray Computed Tomography. Conducted CO2 methanation experiments confirm the predicted trends, if the applied shell is fully closed. Furthermore, mathematical and experimental studies demonstrate, that the inert shell shifts selectivity. Based on this work, safer and yet economical reactor operation is anticipated also for other reaction systems

Finite Action in d5 Gauged Supergravity and Dilatonic Conformal Anomaly for Dual Quantum Field Theory

Gauged supergravity (SG) with single scalar (dilaton) and arbitrary scalar potential is considered. Such dilatonic gravity describes special RG flows in extended SG where scalars lie in one-dimensional submanifold of total space. The surface counterterm and finite action for such gauged SG in three-, four- and five-dimensional asymptotically AdS space are derived. Using finite action and consistent gravitational stress tensor (local surface counterterm prescription) the regularized expressions for free energy, entropy and mass of d4 dilatonic AdS black hole are found. The same calculation is done within standard reference background subtraction. The dilaton-dependent conformal anomaly from d3 and d5 gauged SGs is calculated using AdS/CFT correspondence. Such anomaly should correspond to two- and four-dimensional dual quantum field theory which is classically (not exactly) conformally invariant, respectively. The candidate c-functions from d3 and d5 SGs are suggested. These c-functions which have fixed points in asymptoticaly AdS region are expressed in terms of dilatonic potential and they are positively defined and monotonic for number of potentials.Comment: LaTeX file, 46 pages, two appendixes and some clarifications are adde

"All-fiber" tunable laser in the 2 mu m region, designed for CO2 detection

A stable and tunable thulium-doped “all-fiber” laser offering a narrow linewidth has been created specifically to act as a compact and simple laser source for gaseous CO2 detection. This has been done through a careful design to match the laser output wavelengths to the CO2 absorption lines at 1.875 and 1.997 μm, respectively. A sustainable output power of 11 mW over a tuning range of 7 nm has been obtained by using a combination of a high-reflective fiber Bragg grating with a low-reflective broadband mirror, fabricated at the end of the fiber through silver film deposition. The tuning was achieved using the relaxation-compression mechanism of the fiber Bragg grating, which formed an integral part of the laser resonant cavity. A fiber Bragg grating at 1.548 μm was utilized as a wavelength reference to monitor the tuning of the laser output over the 2 μm wavelength range with a simple and inexpensive interrogator, to avoid the use of an expensive optical spectrum analyzer and to facilitate “in-the-field” operation. This “all-fiber” laser resonator has been shown to be superior in terms of laser tuning range, output power, and linewidth compared to that created with a fiber Bragg grating pair, which was limited by the nonuniform strain transfer to both fiber Bragg gratings

Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations

Biomolecular condensates form via coupled associative and segregative phase transitions of multivalent associative macromolecules. Phase separation coupled to percolation is one example of such transitions. Here, we characterize molecular and mesoscale structural descriptions of condensates formed by intrinsically disordered prion-like low complexity domains (PLCDs). These systems conform to sticker-and-spacers architectures. Stickers are cohesive motifs that drive associative interactions through reversible crosslinking and spacers affect the cooperativity of crosslinking and overall macromolecular solubility. Our computations reproduce experimentally measured sequence-specific phase behaviors of PLCDs. Within simulated condensates, networks of reversible inter-sticker crosslinks organize PLCDs into small-world topologies. The overall dimensions of PLCDs vary with spatial location, being most expanded at and preferring to be oriented perpendicular to the interface. Our results demonstrate that even simple condensates with one type of macromolecule feature inhomogeneous spatial organizations of molecules and interfacial features that likely prime them for biochemical activity