THE ROLE OF PREVIOUS ANTERIOR CRUCIATE LIGAMENT INJURY ON THE VARIABILITY OF JOINT KINEMATICS AND COORDINATION DURING A MATCH SPECIFIC LAND-CUT TASK

This study compared the movement and coordination variability of the previously injured leg of ACL injured subjects (ACLr, n=9), against their non-injured leg and a control (nACL, n=9) leg. The variability of lower limb joint angles and couplings were calculated during a land-cut task (n=20). The previously injured leg had less variability than the noninjured leg in the knee rotation–knee abd-adduction coupling, and more variability than the nACL leg in frontal and transverse knee joint angles and hip rotation–knee abdadduction coupling. Reduced coordination variability could produce a more repetitive loading pattern linked to cartilage degeneration. Increased movement and coordination variability may stem from proprioceptive deficits on the previously injured leg and decrease the ability to adapt to perturbations

Constraining the properties of 1.2-mm dust clumps that contain luminous water masers

We have conducted a sensitive water maser search with the ATCA towards 267 1.2-mm dust clumps presented in the literature. We combine our new observations with previous water maser observations to extend our sample to 294 1.2-mm dust clumps, towards which we detect 165 distinct water maser sites towards 128 1.2-mm dust clumps. Within the fields of our observations, we additionally find four water masers with no apparent associated 1.2-mm dust continuum emission. Our overall detection rate of 44 per cent appears to vary as a function of Galactic longitude. We find that there is an excellent correspondence between the locations of the detected water masers with the peak of the target 1.2-mm dust clump sources. As expected from previous similar studies, the water masers are chiefly detected towards the bigger, brighter and more massive 1.2-mm dust clumps. We find further evidence that the water masers tend to increase in flux density (and therefore luminosity), as well as velocity range, as the sources evolve. We also show that the current sample of water maser sources suffer less from evolutionary biases than previous targeted searches. A higher fraction of dust clump sources in our sample are only associated with water masers (41) than only associated with methanol masers (13). This suggests that water masers can be present at an even earlier evolutionary stage than 6.7-GHz methanol masers. Comparison of the water maser detection rates associated with different combinations of methanol maser and radio continuum, as well as those with neither tracer, shows that the highest detection rate is towards those sources which also exhibit methanol maser emission. We have tested a previously hypothesised model for water maser presence towards 1.2-mm dust clumps. We suggest refinements and future work which will further constrain the nature of the driving sources associated with water masers.Comment: accepted to MNRA

37 GHz methanol masers : Horsemen of the Apocalypse for the class II methanol maser phase?

We report the results of a search for class II methanol masers at 37.7, 38.3 and 38.5 GHz towards a sample of 70 high-mass star formation regions. We primarily searched towards regions known to show emission either from the 107 GHz class II methanol maser transition, or from the 6.035 GHz excited OH transition. We detected maser emission from 13 sources in the 37.7 GHz transition, eight of these being new detections. We detected maser emission from three sources in the 38 GHz transitions, one of which is a new detection. We find that 37.7 GHz methanol masers are only associated with the most luminous 6.7 and 12.2 GHz methanol maser sources, which in turn are hypothesised to be the oldest class II methanol sources. We suggest that the 37.7 GHz methanol masers are associated with a brief evolutionary phase (of 1000-4000 years) prior to the cessation of class II methanol maser activity in the associated high-mass star formation region.Comment: 14 pages, 4 figures, accepted for publication in Ap

Disability as Difference - A Fictional Representation

This study presents three perspectives about how the life experience of individuals with disabilities is profoundly affected by the attitudes of others. A first perspective is presented by three individuals who had sustained significant, traumatic injuries. They each shared with me their experiences with acceptance and the attitudes of others. A second perspective comes from me, as the author of this article. As a person with a virtually lifelong disability, I have interpreted those experiences through a lens mediated by my own relationship to disability. These interpretations have informed a third perspective, that of a fictional representation of the role that the attitudes of others play in the lives of individuals with disabilities. That representation of attitude is presented as a one-act play. Within an oral history framework of narrative inquiry, the play offers a synthesis and restorying of the meanings inherent in each of these individual stories. Its purpose is to provide the reader/audience with a more intimate understanding of disability, demonstrating the relationship between others’ perceptions of disability and its apparently significant and categorical difference from the mainstream. Finally, the implications of this perception of disability as difference are made specific within the context of the ongoing employment challenges that continue to confront individuals living with disabilities

Homosexual Identity, Translation, and Prime-Stevenson\u27s Imre and The Intersexes

In her article Homosexual Identity, Translation, and Prime-Stevenson\u27s Imre and The Intersexes Margaret S. Breen examines the role of translation in lesbian, gay, bisexual, and transgender studies. Breen\u27s focus is Edward Prime-Stevenson, who, under the penname Xavier Mayne, wrote two works: a short novel, Imre: A Memorandum (1906), and a general history of homosexuality, The Intersexes: A History of Similisexualism as a Problem of Social Life (1908). Breen argues that Prime-Stevenson\u27s texts are relevant to late nineteenth- and early twentieth-century discussions of (homo)sexuality because they point to the importance of translation in writings concerning sexual and gender identities and behavior, specifically in lesbian, gay, bisexual, and transgender literature from the late nineteenth century forward

A preliminary examination of the deployment of lean and reverse logistics within the pharmaceutical supply chain (PSC) UK

Drug treatment is the most common form of healthcare intervention and represents the highest non-staff revenue cost in the UK National Health Service (NHS).The annual drugs bill in the UK equates to just about 10% of NHS expenditure (McKee, 2012). Demand for NHS healthcare is effectively infinite (Lodge and Bamford, 2008); there are constant efforts to increase capacity and operational budgets are constrained. One area where hospital pharmacies are looking for cost saving and better services is through improving their Supply Chain Management (SCM) (AT Kearney, 2009). However, they have not only to manage the forward components of the logistics process to minimise waste and maximise patient wellbeing, but to manage the reverse components as well (Jamali et al., 2010). Success in this area can be realised through the application of a Lean Philosophy which focuses on eliminating waste by defining value (Brandao, 2009)

Lower limb kinematics, kinetics and coordination during a land and cut task; the role of gender and previous ACL injury

Anterior cruciate ligament (ACL) injury continues to be a constant adversary to field sports athletes. Females are widely acknowledged as being at an increased risk of ACL injury, in comparison to males. Athletes who are successful in rehabilitation after surgery and return to their sport are reported to have an increased risk of repeated ACL injury and the development of osteoarthritis. The current thesis utilised a novel, maximal drop-jump land and unanticipated cutting task to assess the lower limb biomechanics of uninjured male and females, and previously ACL injured subjects (ACLr). Discrete measures of lower limb kinematics and kinetics were firstly compared between uninjured males and females, and secondly between the previously injured (PI) leg of ACLr subjects and both the contralateral non-injured (NI) leg and an uninjured subject’s control leg. The results show that females had increased hip internal rotation, the PI leg was not significantly different to the NI leg but was different to the control subject’s leg with increased hip flexion, internal knee abduction moment and transverse plane knee ROM. Lower limb coordination was assessed in the ACLr subjects and both legs of the ACLr subjects had similar coordination patterns. The PI leg however showed different coordination patterns than the control subject’s leg for a number of couplings. Movement and coordination variability were also utilised for a gender and ACLr – control comparison. The female subjects and the PI leg had lower levels of movement and coordination variability than males and the contralateral non-injured leg respectively. The PI leg however, had higher levels of movement and coordination variability than the control subject’s leg. In conclusion, females and previously ACL injured subjects may be at an increased risk of initial ACL injury and the development of osteoarthritis on the PI leg respectively, due to lower levels of movement and coordination variability. Altered biomechanics at the hip were also highlighted as a potential mechanism increasing injury risk in females and ACLr subjects

Investigator analytic repeatability of two new intervertebral motion biomarkers for chronic, nonspecific low back pain in a cohort of healthy controls

Background: Understanding the mechanisms underlying chronic, nonspecific low back pain (CNSLBP) is essential to advance personalized care and identify the most appropriate intervention. Recently, two intervertebral motion biomarkers termed “Motion Sharing Inequality” (MSI) and “Motion Sharing Variability” (MSV) have been identified for CNSLBP using quantitative fluoroscopy (QF). The aim of this study was to conduct intra- and inter-investigator analytic repeatability studies to determine the extent to which investigator error affects their measurement in clinical studies.  Methods: A cross-sectional cohort study was conducted using the image sequences of 30 healthy controls who received QF screening during passive recumbent flexion motion. Two independent investigators analysed the image sequences for MSI and MSV from October to November 2018. Intra and inter- investigator repeatability studies were performed using intraclass correlations (ICC), standard errors of measurement (SEM) and minimal differences (MD). Results: Intra-investigator ICCs were 0.90 (0.81,0.95) (SEM 0.029) and 0.78 (0.59,0.89) (SEM 0.020) for MSI and MSV, respectively. Inter-investigator ICCs 0.93 (0.86,0.97) (SEM 0.024) and 0.55 (0.24,0.75) (SEM 0.024). SEMs for MSI and MSV were approximately 10% and 30% of their group means respectively. The MDs for MSI for intra- and inter-investigator repeatability were 0.079 and 0.067, respectively and for MSV 0.055 and 0.067. Conclusions: MSI demonstrated substantial intra- and inter-investigator repeatability, suggesting that investigator input has a minimal influence on its measurement. MSV demonstrated moderate intra-investigator reliability and fair inter-investigator repeatability. Confirmation in patients with CNSLBP is now required