816 research outputs found

    Story time: the benefits of reading together as a family

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    One for the Books: How Reading Improves Your Well-being

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    Article published in Vibrant Life, volume 31, issue 5 under the title One for the Books: How Reading Improves Your Well-being

    Consumo, endeudamiento y ahorro un análisis experimental

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    El consumo tiene un gran impacto a lo largo de la vida de cualquier ser humano. Este trabajo se realiza un estudio experimental aplicado a una muestra de estudiantes de la USFQ, para analizar el grado de impacto de varios factores sobre el consumo, el endeudamiento y el ahorro. Entre estos factores se encuentran las preferencias intertemporales, el sesgo hacia el presente y el problema del autocontrol, conjuntamente con el conocimiento financiero, capacidad de crédito, nivel de independencia socioeconómica de los sujetos, además de la disponibilidad de una tarjeta de crédito. Los resultados demuestran que aquellas personas con mayor factor de descuento en periodos cercanos (más impacientes) poseen patrones de consumo crecientes; los sujetos con información financiera ahorran más y se endeudan menos; y aquellos sujetos a un gasto real alto presentan niveles altos de deuda.El consumo tiene un gran impacto a lo largo de la vida de cualquier ser humano. Este trabajo se realiza un estudio experimental aplicado a una muestra de estudiantes de la USFQ, para analizar el grado de impacto de varios factores sobre el consumo, el endeudamiento y el ahorro. Entre estos factores se encuentran las preferencias intertemporales, el sesgo hacia el presente y el problema del autocontrol, conjuntamente con el conocimiento financiero, capacidad de crédito, nivel de independencia socioeconómica de los sujetos, además de la disponibilidad de una tarjeta de crédito. Los resultados demuestran que aquellas personas con mayor factor de descuento en periodos cercanos (más impacientes) poseen patrones de consumo crecientes; los sujetos con información financiera ahorran más y se endeudan menos; y aquellos sujetos a un gasto real alto presentan niveles altos de deuda

    Enfoque multidisciplinario en la atención de pacientes con enfermedad renal crónica. Una revisión narrativa

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    Chronic renal disease (CRD) is an important public health problem. There is no a national renal health program in Peru. There is evidence that the multidisciplinary model of care in patients with CRD delays progression and reduces all-cause mortality. Although there is no agreement on certain topics, such as at which glomerular filtration rate should the multidisciplinary team work, it is clear that outcomes are improved. Human and financial resources are needed to implement this approach.La enfermedad renal crónica (ERC) es un importante problema de salud pública. En el Perú al momento no existe un programa nacional de salud renal. Existe evidencia que el modelo multidisciplinario de atención en ERC mejora la calidad de atención y ha mostrado que enlentece la progresión de ERC y disminuye la mortalidad por todas las causas. Aunque aún hay puntos controversiales, como, por ejemplo, desde que nivel de tasa de filtración glomerular se debería iniciar el manejo multidisciplinario, es una práctica que ha mejorado la atención y el seguimiento de los pacientes renales. Sin embargo, se requiere para su implementación recursos financieros y profesionales y una capacidad organizativa del sistema de salud, que quizás en nuestro país se convierte en un reto

    Subsidiarity: consolidating principle of the mexican concurrent competence system in environmental matters

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    Esta investigación, tiene como propósito central analizar algunas particularidades, deficiencias y desafíos relativos al sistema de distribución de competencias en nuestro actual régimen federal mexicano, concretamente en materia ambiental. Ello, con la finalidad de seguir en la búsqueda de un diseño institucional más novedoso que permita replantear y consolidar nuestro régimen federal, específicamente, el sistema de competencias concurrentes y, se destaca al principio de subsidiariedad como posible vía para lograrlo.The main purpose of this research is to analyze some particularities, deficiencies and challenges related to the system of distribution of powers in our current Mexican federal regime, specifically in environmental matters. This, with the aim of continuing in the search for a more innovative institutional design that allows us to rethink and consolidate our federal regime, specifically, the system of concurrent powers, and the subsidiarity principle stands out as a possible way to achieve it.Facultad de Ciencias Jurídicas y Sociale

    Hepatocyte growth factor modulates in vitro survival and proliferation of germ cells during postnatal testis development

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    The hepatocyte growth factor (HGF) is a pleiotropic cytokine that influences mitogenesis, motility and differentiation of many different cell types by its tyrosine kinase receptor c-Met. We previously demonstrated that the c-Met/HGF systern is present and functionally active during postnatal testis development. We found also that spermatozoa express c-Met and that HGF has a positive effect on the maintenance of sperm motility. In the present paper, we extend our study on the germ cells at different stages of differentiation during the postnatal development of the testis. We demonstrate that c-met is present in rat spermatogonia, pachytene spermatocytes and round spermatids and that HGF significantly increases spermatogonial proliferation in 8- to 10-day-old prepubertal rats. At this age HGF does not affect Sertoli cells and peritubular myoid cells proliferation. In addition, we studied the effect of the factor on germ cell apoptosis and we show that HGF prevents the genii cell apoptotic process. We also studied the effect of HGF on 18- to 20-day-old and 28- to 30-day-old rat testes. At these ages also the factor significantly increases genii cell duplication and decreases the number of apoptotic cells. However, the effect on programmed cell death is higher in the 8- to 10-day-old rats and declines in the older animals. In conclusion, we report that rat genii cells (spermatogonia, pachytene spermatocytes and round spermatids) express c-met and that HGF modulates genii cell proliferating activity and apoptosis in vitro. These data indicate that the c-Met/HGF system is involved in male germ cell homeostasis and, consequently, has a role in mate fertility

    Isolation as a strategy for controlling the transmission of hepatitis C virus (HCV) infection in haemodialysis units.

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    BACKGROUND: The hepatitis C virus (HCV) infection affects about 2% of the world's population and can cause chronic liver infection and persistent long-term sequelae such as cirrhosis and liver cancer.The prevalence of HCV infection among people on haemodialysis is often higher than the general population. The virus is easily transmitted parenterally, and blood transfusions have previously played a significant role in transmission; however, erythropoietin therapy has reduced the need for transfusions, and coupled with improved screening of donated blood, has significantly decreased transmission by transfusion. Although control of hospital-acquired infection has improved with the advent of biosafety measures, stopping HCV transmission in haemodialysis units remains challenging.Isolating people infected with HCV involves physical separation from others to limit direct or indirect transmission and includes a number of strategies during dialysis. The evidence for isolating people infected with HCV during haemodialysis is sparse with some inconsistencies. OBJECTIVES: To evaluate the benefits and harms of isolation of HCV-infected patients during haemodialysis on the transmission of HCV to other patients. SEARCH METHODS: We searched the Cochrane Kidney and Transplant Specialised Register to 26 November 2015 through contact with the Information Specialist using search terms relevant to this review. We also searched the Latin American and Caribbean Health Sciences Literature Database (LILACS) (1982 to 2015), Web of Science Conference Proceedings Citation Index-Science (CPCI-S, 1990 to 2015), ProQuest Dissertations & Theses Database (1990 to 2015), and Open Grey (1990 to 2015). SELECTION CRITERIA: We included randomised controlled trials (RCTs), quasi-RCTs and cluster RCTs evaluating the clinical benefits and harms of isolating HCV-infected patients during haemodialysis on the transmission of HCV to other patients. We considered incidence of dialysis-acquired HCV infection, all-cause mortality, and adverse effects associated with isolation as the primary outcomes. DATA COLLECTION AND ANALYSIS: Summary estimates of effect were obtained using a random-effects model, and results were expressed as risk ratios (RR) and their 95% confidence intervals (CI) for dichotomous outcomes, and mean difference (MD) or standardised mean difference (SMD) and 95% CI for continuous outcomes. MAIN RESULTS: Only one study, which included 12 centres was identified: four centres used dedicated haemodialysis machines for HCV-infected patients and eight centres used non-dedicated machines. The total number of patients enrolled was 593. One centre was excluded after randomisation. Random sequence generation was not described and allocation concealment was not performed. Participants and personnel were not blinded and blinding of outcome assessors was not reported. Only 74.5% of the patients were followed for 9 months; and 47.3% were followed for an additional 9 months. The authors only reported one outcome, measuring the difference in the incidence of HCV in both groups. The authors did not consider the exposure time, to determine the adjusted rate of seroconversion risk/patient-year. The study reported that the incidence of HCV infection during the first follow-up period (9 months) was 1.6% in the dedicated group, and 4.7% in the non-dedicated one (446 patients analysed out of 593 randomised; RR 0.34, 95% CI 0.11 to 1.07). During the second follow-up period (18 months) the incidence was 1.3% in the dedicated group and 5.8% in the control (281 patients analysed out of 593 randomised; RR 0.22, 95% CI 0.05 to 1.02). Therefore, we found no differences in terms of the number of participants developing HCV infection when comparing the dedicated group with the usual care. Moreover, the evidence was of very low quality, which means that we have very little confidence in the effect estimate. AUTHORS' CONCLUSIONS: The benefits and harms of isolation of HCV-infected patients during haemodialysis on the transmission of HCV to other patients are uncertain. Evidence from one short-duration cluster-randomised study with a high risk of bias did not find differences in terms of the number of participants developing HCV infection when comparing the use of dedicated haemodialysis machines for HCV infected patients with the use of non-dedicated machines.post-print398 K

    Trabajo de investigación previo a la obtención del Grado de Magister en Ciencias de la Educación, mención Educación Parvularia

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    La investigación sobre el tema del egocentrismo infantil en el desarrollo intelectual del niño de tres a cuatro años del Instituto Particular Vigotsky de la ciudad de Riobamba tiene como objetivo general reflexionar sobre la relación entre el egocentrismo infantil y el desarrollo intelectual de los niños y niñas de 3 a 4 años del Instituto Particular Vygotsky. La investigación ha fundamentado las bases bibliográficas tanto sobre el egocentrismo infantil como sobre el desarrollo intelectual de niños y niñas de 3 a 4 años de edad. El propósito de la investigación es establecer las causas del egocentrismo infantil y su repercusión en el desarrollo intelectual de los niños/as del Instituto Particular Vigotsky, y así plantear una alternativa de solución a esta problemática educativa y social. Considerando que la investigación de campo reveló un correlación entre las dos variables estudiadas se procedió a diseñar una propuesta de solución a esta problemática planteando una Guía de técnicas orientadas a los Padres de Familia y Maestras para mitigar el egocentrismo y mejorar el desarrollo intelectual de los niños/as de la Unidad Educativa “LeontievVigotsky”.Con la guía desarrollada se espera que esta situación pueda ser mitigada contribuyendo de esta manera a un desarrollo intelectual más apropiado para los niños y niñas motivo de este estudio
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