Technoference: Parent Distraction With Technology and Associations With Child Behavior Problems

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141477/1/cdev12822.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141477/2/cdev12822_am.pd

"Technoference" and Implications for Mothers' and Fathers' Couple and Coparenting Relationship Quality

Technology devices are widely used today, creating opportunities to connect and communicate with distant others while also potentially disrupting communication and interactions between those who are physically present (i.e., technoference or phubbing). These disruptions in couple and coparenting relationships have the potential to negatively impact relationship outcomes. In this two-part study of 182 married/cohabiting couples from the Daily Family Life Project and 239 couples from the Couple Well-Being Project, we examined the role of technoference in couple and coparenting relationship quality and potential gender differences utilizing dyadic data. We found that greater technoference related to greater conflict over technology use, and greater conflict predicted lower relationship satisfaction and poorer perceptions of coparenting quality (Study 1). Using a more diverse sample (Study 2), we again found support for the main pathways tested in our first study, suggesting that results found in Study 1 and in previous work are not artifacts of sampling. As satisfaction, support, and agreement among relationship partners and parents are often critical to relationship health and family cohesion, it is important for couples and families to evaluate, monitor, and be willing to adapt their technology usage patterns so that these patterns do not cause conflict and possibly relationship deterioration over tim

Mindful Parenting and Parent Technology Use: Examining the Intersections and Outlining Future Research Directions

Popular media attention and scientific research in both mindful parenting and technology use in the context of parenting has expanded in the 21st century; however, these two streams of research have largely evolved separately from one another. Thus, in this conceptual paper, we integrate the research on mindful parenting with that on parents’ technology use and parenting to examine how parent technology use may impact or be linked with aspects of mindful parenting. Mindful parenting theory outlines five key components: listening with full attention, self-regulation in the parent–child relationship, emotional awareness of self and child, nonjudgmental acceptance of self and child, and compassion for self and child. Parent technology use, in particular the use of mobile devices, has the potential to impact all five elements of mindful parenting. However, the relationship between mindful parenting and technology is complex, and there can be both positive and negative implications of parent technology use on mindful parenting. On the positive side, technology use might help parents regulate their emotions; access support; and develop more empathy, acceptance, and compassion for themselves and their children. Yet, parent technology use also has the potential to create distractions and disrupt parent–child interactions, which may make it more difficult for parents to listen with full attention, maintain awareness of their own and their child’s emotions, and calmly respond to child behaviors with intentionality. Technology use may also create more opportunities for social comparisons and judgement, making it more difficult for parents to accept their children nonjudgmentally and have compassion for their children as they are. Future research is needed to understand the conditions under which technology use can hinder or promote mindful parenting and how interventions can promote mindful parenting skills and a positive uses of technology

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two

Background The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd. Methods We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background. Results First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001). Conclusions In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival

Mindful Parenting and Parent Technology Use: Examining the Intersections and Outlining Future Research Directions

Popular media attention and scientific research in both mindful parenting and technology use in the context of parenting has expanded in the 21st century; however, these two streams of research have largely evolved separately from one another. Thus, in this conceptual paper, we integrate the research on mindful parenting with that on parents&rsquo; technology use and parenting to examine how parent technology use may impact or be linked with aspects of mindful parenting. Mindful parenting theory outlines five key components: listening with full attention, self-regulation in the parent&ndash;child relationship, emotional awareness of self and child, nonjudgmental acceptance of self and child, and compassion for self and child. Parent technology use, in particular the use of mobile devices, has the potential to impact all five elements of mindful parenting. However, the relationship between mindful parenting and technology is complex, and there can be both positive and negative implications of parent technology use on mindful parenting. On the positive side, technology use might help parents regulate their emotions; access support; and develop more empathy, acceptance, and compassion for themselves and their children. Yet, parent technology use also has the potential to create distractions and disrupt parent&ndash;child interactions, which may make it more difficult for parents to listen with full attention, maintain awareness of their own and their child&rsquo;s emotions, and calmly respond to child behaviors with intentionality. Technology use may also create more opportunities for social comparisons and judgement, making it more difficult for parents to accept their children nonjudgmentally and have compassion for their children as they are. Future research is needed to understand the conditions under which technology use can hinder or promote mindful parenting and how interventions can promote mindful parenting skills and a positive uses of technology

Result tables for Social media activity and its impact on career-related perceptions

These tables represent the findings presented in the brief article published in the journal Development and Learning in Organizations

Is it fair to simply tell parents to use their phones less? A qualitative analysis of parent phone use

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/169246/1/apa15893_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/169246/2/apa15893.pd

Is it fair to simply tell parents to use their phones less? A qualitative analysis of parent phone use

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/169246/1/apa15893_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/169246/2/apa15893.pd