The effect of prosody on decision making

MPA Regional Research AwardThis study sought to induce mood through affective prosody and then measure whether this had a significant effect on decision making. Prosody can be defined as tone, rate, or stress patterns that occur during speech. Prosody, when used to convey emotion, is termed affective prosody. Prior research suggests that mood is a viable predictor of performance on risky decision making tasks. More specifically, positive mood has been linked with heuristic processing, which relies on emotional reasoning. Initially, individuals feel more averse to losses and more pleased with wins, leading to more advantageous decision making. Negative emotion has been linked with substantive/systematic processing; individuals tend to exhibit more disadvantageous decision making initially in an effort to determine the most favorable outcome. This study investigated whether affective prosody alone could directly induce mood and thereby alter performance on an unrelated decision making task. This study utilized the Hungry Donkey Task, which is adapted for use with both children and adults to measure risk taking. It was hypothesized that adults induced with positive affective prosody would make more favorable decisions in early trials, while those induced with negative affective prosody would make riskier decisions initially. Mood was successfully induced with affective prosody such that participants in the positive condition reported more positive self-report mood than the negative condition. Results do not support the hypothesis; rather display negative affective prosody as eliciting better decision making in both the early and later trials. This may be a result of the positive condition relying on heuristic processing, which may have led to less advantageous decisions. This study helps build a greater understanding of the effects of mood on risky decision making and lends support to the claim that affective prosody can serve as an influencing factor in others’ behavior.No embargoAcademic Major: Psycholog

Educational fusion : an instructional, web-based, software development platform

Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science; and, Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1998.Includes bibliographical references (p. 96-98).by Brandon W. Porter.B.S.M.Eng

An Application and Refinement of the Karst Disturbance Index through Evaluating Variability in Island Karst Disturbance in Puerto Rico

Karst environments are unique landscapes that contain important resources, including freshwater aquifers and specialized ecosystems, which are easily disturbed due to the interconnected nature of the surface and subsurface. The anthropogenic impacts on karst are deleterious to the ecosystems that are dependent on the karst environment and also to groundwater supplies. The Karst Disturbance Index (KDI) is a holistic tool used to measure anthropogenic impacts associated with karst environments, which has been applied and refined through studies performed in Florida and Italy, yet still remains untested and susceptible to modification for other areas. Application of the KDI in Arecibo, Puerto Rico, which is geographically isolated, and highly vulnerable due to its sensitive karst resources, provides an opportunity to test the index in an island setting. This research resulted in two KDI scores for the study area using both the original and recently modified methods. The scores reflect a significant to severe disturbance to the municipality’s karst environment of 0.54 and 0.68, respectively. Issues regarding the KDI were found from the application and comparison of these methodologies and revealed the need for adding additional indicators, including Mogote Removal and Coastal Karst, as well as several additional refinements and recommendations pertaining to scale, weighting, and incorporating the two methods together to create a single, more practical KDI tool. The disseminated results of the assessment of the area using the KDI will educate and help to foster stewardship of this vital resource in Puerto Rico

The Long-Term Outcomes after Radical Prostatectomy of Patients with Pathologic Gleason 8–10 Disease

Background. We explored the long-term clinical outcomes including metastases-free survival and prostate cancer-specific survival (PCSS) in patients with pathologic Gleason 8–10 disease after radical prostatectomy (RP). Methods. We report on 91 patients with PCSS data with a median followup of 8.2 years after RP performed between 1988 and 1997. Cox regression and Kaplan-Meier analysis were used to evaluate year of surgery, pathologic stage, and surgical margin status as predictors of PCSM. Results. Median age was 65 years (IQR: 61–9), and median PSA was 9.7 ng/ml (IQR: 6.1–13.4). Of all patients, 62 (68.9%) had stage T3 disease or higher, and 48 (52.7%) had a positive surgical margin. On multivariate analysis, none of the predictors were statistically significant. Of all patients, the predicted 10-year BCR-free survival, mets-free survival, and PCSS were 59% (CI: 53%–65%), 88% (CI: 84%–92%), and 94% (CI: 91%–97%), respectively. Conclusions. We have demonstrated that cancer control is durable even 10 years after RP in those with pathologic Gleason 8–10 disease. Although 40% will succumb to BCR, only 6% of patients died of their disease. These results support the use of RP for patients with high-risk localized prostate cancer

The Sanctifying Work of the Holy Spirit: Revisiting Alston’s Interpersonal Model

Of the various loci of systematic theology that call for sustained philosophical investigation, the doctrine of sanctification stands out as a prime candidate.  In response to that call, William Alston developed three models of the sanctifying work of the Holy Spirit: the fiat model, the interpersonal model, and the sharing model.  In response to Alston’s argument for the sharing model, this paper offers grounds for a reconsideration of the interpersonal model.  We close with a discussion of some of the implications of one’s understanding of the transforming work of the Holy Spirit for practical Christian spirituality

Development of behavioral preferences for the optimal choice following unexpected reward omission is mediated by a reduction of D 2‐like receptor tone in the nucleus accumbens

To survive in a dynamic environment, animals must identify changes in resource availability and rapidly apply adaptive strategies to obtain resources that promote survival. We have utilised a behavioral paradigm to assess differences in foraging strategy when resource (reward) availability unexpectedly changes. When reward magnitude was reduced by 50% (receive one reward pellet instead of two), male and female rats developed a preference for the optimal choice by the second session. However, when an expected reward was omitted (receive no reward pellets instead of one), subjects displayed a robust preference for the optimal choice during the very first session. Previous research shows that, when an expected reward is omitted, dopamine neurons phasically decrease their firing rate, which is hypothesised to decrease dopamine release preferentially affecting D 2‐like receptors. As robust changes in behavioral preference were specific to reward omission, we tested this hypothesis and the functional role of D 1‐ and D 2‐like receptors in the nucleus accumbens in mediating the rapid development of a behavioral preference for the rewarded option during reward omission in male rats. Blockade of both receptor types had no effect on this behavior; however, holding D 2‐like, but not D 1‐like, receptor tone via infusion of dopamine receptor agonists prevented the development of the preference for the rewarded option during reward omission. These results demonstrate that avoiding an outcome that has been tagged with aversive motivational properties is facilitated through decreased dopamine transmission and subsequent functional disruption of D 2‐like, but not D 1‐like, receptor tone in the nucleus accumbens. This study investigates the role of dopamine receptors in the nucleus accumbens in altering behavior in response to the omission of an expected reward. Similarly to controls, multiple doses of a D 1‐like receptor agonist, D 1‐like receptor antagonist, and D 2‐like receptor antagonist do not prevent subjects from developing a robust behavioral preference for the rewarded lever and avoiding the omitted‐reward lever during the first session of reward omission. However, the D 2‐like agonist quinpirole dose‐dependently blocks a behavioral preference for the rewarded lever, suggesting that reductions in D 2‐like receptor tone are necessary for altering behavior away from an aversive option and toward the optimal choice.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99645/1/ejn12253.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/99645/2/ejn12253-sup-0001-Supplement.pd

Spectrally and Radiometrically Stable, Wideband, Onboard Calibration Source

The Onboard Calibration (OBC) source incorporates a medical/scientific-grade halogen source with a precisely designed fiber coupling system, and a fiber-based intensity-monitoring feedback loop that results in radiometric and spectral stabilities to within less than 0.3 percent over a 15-hour period. The airborne imaging spectrometer systems developed at the Jet Propulsion Laboratory incorporate OBC sources to provide auxiliary in-use system calibration data. The use of the OBC source will provide a significant increase in the quantitative accuracy, reliability, and resulting utility of the spectral data collected from current and future imaging spectrometer instruments

Dopamine and opioid systems interact within the nucleus accumbens to maintain monogamous pair bonds

Prairie vole breeder pairs form monogamous pair bonds, which are maintained through the expression of selective aggression toward novel conspecifics. Here, we utilize behavioral and anatomical techniques to extend the current understanding of neural mechanisms that mediate pair bond maintenance. For both sexes, we show that pair bonding up-regulates mRNA expression for genes encoding D1-like dopamine (DA) receptors and dynorphin as well as enhances stimulated DA release within the nucleus accumbens (NAc). We next show that D1-like receptor regulation of selective aggression is mediated through downstream activation of kappa-opioid receptors (KORs) and that activation of these receptors mediates social avoidance. Finally, we also identified sex-specific alterations in KOR binding density within the NAc shell of paired males and demonstrate that this alteration contributes to the neuroprotective effect of pair bonding against drug reward. Together, these findings suggest motivational and valence processing systems interact to mediate the maintenance of social bonds