Risk-based system to control safety level of flooded passenger ships

Predicting the consequences of flooding is a key issue that may help the ship master of a large passenger ship to make rational decisions in emergency situations. To this end, the Delphi Emergency Decision Support System (Delphi EDSS) has been designed and is under implementation to continuously assess ship's state of survivability. Analyses are performed by means of a time-domain simulation program, where transient stages of flooding are investigated and stored off-line for all the potential damage scenarios. The Delphi EDSS evaluates the ship risk level including the most important aspects related to safety state while establishing the time-to-capsize which is of primary concern for the safe evacuation of the damaged ship. The methodology is based on a scientific approach, setting an overall platform for rational assessment of non-survivability risk. Determination of the global risk level and its components requires solution of a multicriterial problem, where the level of importance of each criterion contributing to determination of a global risk index is combined with fuzzified contributors to risk calculated at lower levels

Integrated use of local and technical soil quality indicators and participatory techniques to select them. A review of bib-liography and analysis of research strategies and outcomes

Climate change has strong impacts on soil conservation and agricultural productivity, with severe consequences on smallholders in developing countries, but virtually no research has been carried out so far on this issue. Therefore, it is necessary to foster the implementation of participatory projects to help communities deal with new difficulties. Sustainable soil management can reduce and even reverse land degradation, helping farmers to adapt to climate change effects. Pro-gress toward sustainability cannot be implemented in small rural communities regardless of local knowledge, which can be addressed using participatory techniques. To this purpose the choice and use of indicators is essential to carry out correct assessments of soil vulnerability integrating local and technical knowledge. The purpose of this review was to study how the problem of building a set of integrated indicators to assess soil quality has been addressed so far and which participatory techniques have been more successfully employed, analyzing studies carried out in rural communities of developing countries. We found out that there is a lack of participated studies dealing with environmental issues. Those that do so address them only indirectly, being centered on present agricultural problems. The studies rarely feature a collaboration with social science experts, consequently the use of participatory techniques lacks protocols and a standardized nomenclature to help in the transfer and generalization of experiences. Women are rarely involved and nearly exclusively in African countries: this could be related to social and cultural conditions, but needs more atten-tion. Different aspects need to be improved to help the implementation of a successful approach in future projects. This review provides a tool to facilitate future interdisciplinary research on integration of local and scientific knowledge and will help to devise more successful strategies to tackle the challenges posed by climate change to smallholders in developing countries

The sexuality-assemblages of young men: a new materialist analysis

This article presents a new materialist exploration of young men and sexuality that shifts the focus away from bodies and individuals, toward the affective flow within assemblages of bodies, things, ideas and social institutions, and the sexual capacities this flow produces. Using data from two empirical studies, we explore the sexuality assemblages of teen boys and young men, and the micropolitics of these assemblages. We find that the sexuality produced in the bodies of young men is highly territorialised and aggregated by various materialities. However, we also reveal how young men resist these conventional sexualities

Nonlinear Gamow vectors in nonlocal optical propagation

Shock waves dominate in a wide variety of fields in physics dealing with nonlinear phenomena, nevertheless the description of their evolution is not resolved for the entire dynamics. Here we propose an analytical method based on Gamow vectors, which belong to irreversible quantum mechanics. We theoretically and experimentally show the appearance of these decaying states during shock evolution allowing to describe the whole wave propagation. These results open new ways to the control of extreme nonlinear regimes such as supercontinuum generation or in the analogies of fundamental physical theories

An Application of Modular Design in the Refitting of a Hybrid-electric Propelled Training Ship

Nowadays specific ships are used to train students as sailors. As historical vessels are conveniently employed to this aim, the average age of these ships is usually high. In order to amortize operating and maintenance costs, the training ships\u2019 ownership (except for naval ones) is shared among multiple entities and schools. Moreover, generally these vessels are used in coastal navigation. The consequent operational profile imposes the need to rearrange the ship internal spaces according to the shipowner who will use it. Considering all these reasons, a modular design approach can be adopted in the refitting process, while reverse engineering techniques and integrated design tools should be used for the reconstruction when the original technical documentation is not available. In this context, hybrid-electric propulsion systems can be proposed as effective to enable the Zero Emission Mode, thus reducing the vessel\u2019s environmental impact during the training. By doing this, three goals are achieved to extend the ship operational life: ease of rearrangement of the internal spaces for different uses, reduction of operating/maintenance costs and eco-sustainability in coastal navigation. In this paper, after a description about modular design and hybrid electric technologies, the refitting project of the M/N \u201cUmberto d\u2019Ancona\u201d is discussed. The latter is the training ship of \u201cTomaso di Savoia Duke of Genoa\u201d, the nautical institute in Trieste, Italy

Inside the research-assemblage: new materialism and the micropolitics of social inquiry

This paper explores social inquiry in terms of the ‘research-assemblages’ that produce knowledge from events. We use the precepts of new materialism (and specifically DeleuzoGuattarian assemblage ontology) to develop understanding of what happens when social events are researched. From this perspective, research is not at root an enterprise undertaken by human actors, but a machine-like assemblage of things, people, ideas, social collectivities and institutions. During social inquiry, the affect economies of an event-assemblage and a research-assemblage hybridise, generating a third assemblage with its own affective flow. This model of the research-assemblage reveals a micropolitics of social research that suggests a means to interrogate and effectively reverse-engineer different social research methodologies and methods, to analyse what they do, how they work and their micropolitical effects. It also suggests a means to forward-engineer research methods and designs to manipulate the kinds of knowledge produced when events are researched

DMBT1 expression is down-regulated in breast cancer.

BACKGROUND: We studied the expression of DMBT1 (deleted in malignant brain tumor 1), a putative tumor suppressor gene, in normal, proliferative, and malignant breast epithelium and its possible relation to cell cycle. METHODS: Sections from 17 benign lesions and 55 carcinomas were immunostained with anti DMBT1 antibody (DMBTh12) and sections from 36 samples, were double-stained also with anti MCM5, one of the 6 pre-replicative complex proteins with cell proliferation-licensing functions. DMBT1 gene expression at mRNA level was assessed by RT-PCR in frozen tissues samples from 39 patients. RESULTS: Normal glands and hyperplastic epithelium in benign lesions displayed a luminal polarized DMBTh12 immunoreactivity. Normal and hyperplastic epithelium adjacent to carcinomas showed a loss of polarization, with immunostaining present in basal and perinuclear cytoplasmic compartments. DMBT1 protein expression was down-regulated in the cancerous lesions compared to the normal and/or hyperplastic epithelium adjacent to carcinomas (3/55 positive carcinomas versus 33/42 positive normal/hyperplastic epithelia; p = 0.0001). In 72% of cases RT-PCR confirmed immunohistochemical results. Most of normal and hyperplastic mammary cells positive with DMBTh12 were also MCM5-positive. CONCLUSIONS: The redistribution and up-regulation of DMBT1 in normal and hyperplastic tissues flanking malignant tumours and its down-regulation in carcinomas suggests a potential role in breast cancer. Moreover, the concomitant expression of DMTB1 and MCM5 suggests its possible association with the cell-cycle regulation

Mixed methods, materialism and the micropolitics of the research-assemblage

We assess the potential for mixing social research methods, based upon a materialist and micropolitical analysis of the research-assemblage and of what individual research techniques and methods do in practice. Applying a DeleuzoGuattarian toolkit of assemblages, affects and capacities, we document what happens when research methods and techniques interact with the events they wish to study. Micropolitically, many of these techniques and methods have unintended effects of specifying and aggregating events, with the consequently that the knowledge produced by social inquiry is invested with these specifications and aggregations. We argue that rather than abandoning these social research tools, we may use the micropolitical analysis to assess precisely how each method affects knowledge production, and engineer the research designs we use accordingly. This forms the justification for mixing methods that are highly aggregative or specifying with those that are less so, effectively rehabilitating methods that have often been rejected by social researchers, including surveys and experiments

Draft Genome Sequences of Eight Bacilli Isolated from an Ancient Roman Amphora

Paleomicrobiology, the study of ancient microbiological material, allows us to understand different evolutionary phenomena in bacteria. In this study, eight bacilli isolated from an ancient Roman amphora, which dates to the IV to V sec. AD, were sequenced and functionally annotated