Impaired Dendritic Expression and Plasticity Of H-Channels in the fmr1(-/Y) Mouse Model of Fragile X Syndrome

Despite extensive research into both synaptic and morphological changes, surprisingly little is known about dendritic function in fragile X syndrome (FXS). We found that the dendritic input resistance of CA1 neurons was significantly lower in fmr1(-/y) versus wild-type mice. Consistent with elevated dendritic I-h, voltage sag, rebound, and resonance frequency were significantly higher and temporal summation was lower in the dendrites of fmr1(-/y) mice. Dendritic expression of the h-channel subunit HCN1, but not HCN2, was higher in the CA1 region of fmr1(-/y) mice. Interestingly, whereas mGluR-mediated persistent decreases in Ih occurred in both wildtype and fmr1(-/y) mice, persistent increases in Ih that occurred after LTP induction in wild-type mice were absent in fmr1(-/y) mice. Thus, chronic upregulation of dendritic Ih in conjunction with impairment of homeostatic h-channel plasticity represents a dendritic channelopathy in this model of mental retardation and may provide a mechanism for the cognitive impairment associated with FXS.FRAXAUniversity of Texas Austin Undergraduate Research FellowshipNational Institutes of Health Grant MH048432Center for Learning and Memor

On the Dynamics of a Two-Parameter Family of Piecewise Linear Maps

This paper concerns the mapping defined by Tab(x) = minjax, b(l- x], I} (p) where a \u3e O} b \u3e O} and 0 x 1. When ab a + b, this relationship is also represented by the equation {axJ 0 X a:b Tab(x) = b bel-x)} - a + b

Approaches in Teaching Advanced Placement Spanish

The curriculum developed in this project has been designed specifically for Advanced Placement Spanish students, although lt may be used ln almost any advanced foreign language class. In addition to building on prior knowledge and increasing target language proficiency, this curriculum attempts to prepare students to take the Advanced Placement Spanish Language Exam

23 Framework Things: Minnesota Librarians on the Cutting Edge of Information Literacy Practice

ACRL released the new Framework for Information Literacy for Higher Education in 2015, and since then librarians nationwide have been seeking support and resources for how to implement these new best practices at their institution and in their teaching practice. MLA\u27s Instruction RoundTable (IRT) responded by creating 23 Framework Things (https://23frameworkthings.wordpress.com/), an online professional development opportunity that helps Minnesota librarians learn about the Framework, engage with it through activities, earn prizes/badges, and share strategies with an emerging community of practice. This session will feature a showcase of librarians from different types of academic institutions, large and small, sharing how they have engaged with the Framework though their participation in 23 Framework Things. Come to learn and leave inspired by Minnesota librarians on the cutting edge of information literacy instruction

Meeting Users Where They Are: Teaching Information Literacy Online

In the digital age, libraries need to reach their users where they are. Increasingly, that means providing online parallels to what has been traditionally offered by libraries face-to-face. The current co-chairs of the MLA’s Instruction Round Table sought to develop a community of practice around this issue to develop structure and support for delivering instruction online. Participants will gain hands-on experience developing a plan to turn face-to-face instruction into the online environment. Session participants will walk away with a clear concept of how to improve their approach to online information literacy instruction

Form, Function, and the Right Tools: Effective Publications for the Accidental Designer

You no longer need to be a graphic designer to create professional-looking publications. It\u27s easy with a few simple software tools and an introduction to graphic design. In this session, participants will learn to use Microsoft Publisher, Paint, and Snipping Tool to create a flyer to take back to their library. Along the way, they will be introduced to graphic design elements, including fonts, color, and composition, to bring their marketing materials to the next level

Delivering Course Materials Inside the LMS: An ITS and Libraries Partnership

This poster details a partnership at the University of St. Thomas that embodies the university’s vision of digital transformation. At St. Thomas, the University Libraries and Information Technology Services are collaborating on an effort to implement and market a system that is built on top of the Libraries’ system and delivers course readings via Canvas, the campus’s learning management system. To avoid the negative effects expensive course materials have on student success, this collaboration directly addresses the question of affordability by utilizing existing university investments in library resources so students aren’t “paying twice.” Additionally, centralizing the readings in Canvas makes it clear to students what they need to read and how to access it. For faculty, the system offers a streamlined way to manage course readings and collaborate with librarians, while also providing an avenue to acquire and deliver copyrighted content that requires licensing when needed. The system also offers a better alternative for online and blended learning courses to fold in academic support services. Using metrics available in this system, faculty can pinpoint which readings students are engaging with, and can make adjustments as they see fit

Finding Common Ground: Creating Community & Connections around Information Literacy

How can school media specialists, technology specialists, and academic librarians collaborate to build students’ college readiness and support lifelong information literacy learning? The development of the Association of College & Research Libraries (ACRL) Framework for Information Literacy for Higher Education and the American Association of School Librarians (AASL) Standards Framework for Learners provides new opportunities for school and academic librarians to find common ground. In this session, three current and former chairs of the Minnesota Library Association Instruction Roundtable will explore connections between these two guiding documents and the ways in which they approach information literacy. Building on these connections, presenters will offer practical strategies for engaging in ongoing professional development and building communities of practice around the ACRL and AASL Frameworks