The Lick AGN Monitoring Project 2011: Dynamical Modeling of the Broad Line Region in Mrk 50

We present dynamical modeling of the broad line region (BLR) in the Seyfert 1 galaxy Mrk 50 using reverberation mapping data taken as part of the Lick AGN Monitoring Project (LAMP) 2011. We model the reverberation mapping data directly, constraining the geometry and kinematics of the BLR, as well as deriving a black hole mass estimate that does not depend on a normalizing factor or virial coefficient. We find that the geometry of the BLR in Mrk 50 is a nearly face-on thick disk, with a mean radius of 9.6(+1.2,-0.9) light days, a width of the BLR of 6.9(+1.2,-1.1) light days, and a disk opening angle of 25\pm10 degrees above the plane. We also constrain the inclination angle to be 9(+7,-5) degrees, close to face-on. Finally, the black hole mass of Mrk 50 is inferred to be log10(M(BH)/Msun) = 7.57(+0.44,-0.27). By comparison to the virial black hole mass estimate from traditional reverberation mapping analysis, we find the normalizing constant (virial coefficient) to be log10(f) = 0.78(+0.44,-0.27), consistent with the commonly adopted mean value of 0.74 based on aligning the M(BH)-{\sigma}* relation for AGN and quiescent galaxies. While our dynamical model includes the possibility of a net inflow or outflow in the BLR, we cannot distinguish between these two scenarios.Comment: Accepted for publication in ApJ. 8 pages, 6 figure

Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease

Objective: To determine the motor phenotype of LRRK2 G2019S mutation carriers. LRRK2 mutation carriers were previously reported to manifest the tremor dominant motor phenotype, which has been associated with slower motor progression and less cognitive impairment compared with the postural instability and gait difficulty (PIGD) phenotype. Design: Cross-sectional observational study. Setting: Thirteen movement disorders centers. Participants: Nine hundred twenty-five early-onset Parkinson disease cases defined as age at onset younger than 51 years. Main Outcome Measures: LRRK2 mutation status and Parkinson disease motor phenotype: tremor dominant or PIGD. Demographic information, family history of Parkinson disease, and the Unified Parkinson's Disease Rating Scale score were collected on all participants. DNA samples were genotyped for LRRK2 mutations (G2019S, I2020T, R1441C, and Y1699C). Logistic regression was used to examine associations of G2019S mutation status with motor phenotype adjusting for disease duration, Ashkenazi Jewish ancestry, levodopa dose, and family history of Parkinson disease. Results: Thirty-four cases (3.7%) (14 previously reported) were G2019S carriers. No other mutations were found. Carriers were more likely to be Ashkenazi Jewish (55.9% vs 11.9%; P < .001) but did not significantly differ in any other demographic or disease characteristics. Carriers had a lower tremor score (P = .03) and were more likely to have a PIGD phenotype (92.3% vs 58.9%; P = .003). The association of the G2019S mutation with PIGD phenotype remained after controlling for disease duration and Ashkenazi Jewish ancestry (odds ratio, 17.7; P < .001). Conclusion: Early-onset Parkinson disease G2019S LRRK2 carriers are more likely to manifest the PIGD phenotype, which may have implications for disease course

Capstone Design - Parking Garage (semester?), IPRO 315: Capstone Parking Garage IPRO 315 Project Plan F06

The plan for this IPRO is to develop a design for a large scale parking garage that can accommodate about 500 cars and will be located on IIT’s main campus. The objective of this project is to develop a design that is applicable to today’s lifestyles, yet goes beyond the standard parking systems currently used. Features including quick handling of incoming and outgoing cars, efficiency in storage, and aesthetics are all considered in design. Basically, the aim is to develop an innovative and economical concept for parking a car.Deliverables for IPRO 315: Capstone Design - Parking Garage for the Fall 2006 semeste

Capstone Design - Parking Garage (semester?), IPRO 315

The plan for this IPRO is to develop a design for a large scale parking garage that can accommodate about 500 cars and will be located on IIT’s main campus. The objective of this project is to develop a design that is applicable to today’s lifestyles, yet goes beyond the standard parking systems currently used. Features including quick handling of incoming and outgoing cars, efficiency in storage, and aesthetics are all considered in design. Basically, the aim is to develop an innovative and economical concept for parking a car.Deliverables for IPRO 315: Capstone Design - Parking Garage for the Fall 2006 semeste

Capstone Design - Parking Garage (semester?), IPRO 315: Capstone Parking Garage IPRO 315 Midterm Report F06

The plan for this IPRO is to develop a design for a large scale parking garage that can accommodate about 500 cars and will be located on IIT’s main campus. The objective of this project is to develop a design that is applicable to today’s lifestyles, yet goes beyond the standard parking systems currently used. Features including quick handling of incoming and outgoing cars, efficiency in storage, and aesthetics are all considered in design. Basically, the aim is to develop an innovative and economical concept for parking a car.Deliverables for IPRO 315: Capstone Design - Parking Garage for the Fall 2006 semeste