Internet scheduling environment with market-driven agents

This paper describes a new generation scheduling paradigm, the Internet scheduling environment. It is formed by a group of Internet scheduling agents which share computational resources to solve scheduling problems in a distributed and collaborative manner. We propose a migration scheme to transform existing standalone scheduling systems to Internet scheduling agents that can communicate with each other and solve problems beyond individual capabilities. To coordinate computational resource collaboration among agents, we introduce the market-based control mechanism is which self-interested agents initiate or participate in auctions to sell or buy scheduling problems. Efficient allocation of computational resources is achieved through the auctions. This paper also describes a prototype Internet scheduling environment named LekiNET, which is migrated from LEKIN®, a flexible job shop scheduling system. The experiments on the LekiNET testbed demonstrate that the agent-based market-driven Internet scheduling environment is feasible and advantageous to future scheduling research and development.published_or_final_versio

A hierarchical assessment method using bayesian network for material risk detection on green supply chain

Today's social awareness of environmental protection presents the electronic companies with an irreversible trend towards green manufacturing. It raises harsh requirement for the sourcing process and imposes unprecedented pressure to the QA system, majorly due to the risk of hazardous material. As QA procedures are becoming more complicated for coping with increasing material risk and meanwhile the time and resource available are tightly constrained, the development of an effective mechanism for material testing turns up to be a critical issue. In this study, a hierarchical material risk assessment approach is proposed based on FMEA framework. Taking into account the risk occurrence, the difficulty in detection and the severity the risk causes, it enables companies to estimate their material risks dynamically using Bayesian network. With its help, companies can assess and prioritize the material risk in a systematic and efficient manner which will drive QA towards a more high-performance process. ©2010 IEEE.published_or_final_versionThe IEEE International Conference on Industrial Engineering and Engineering Management (IEEM 2010), Macao, China, 7-10 December 2010. In Proceedings of IEEM, 2010, p. 1184-118

Virtual objects in electronic catalogs: A human-computer interface issue

Web interface design is an important aspect of electronic commerce (EC). However, apart from design frameworks and guidelines for Web-based EC, not much has been done by researchers or practitioners on how electronic catalogs (e-catalogs) influence the users' desirability and satisfaction as purchasers. In this correspondence, we investigate the form of media that represented the most efficient mode to present products to Web users by summarizing and evaluating various existing forms of e-catalogs and their respective responses from Web users. We conclude that a 3-D virtual object (VO) is the most efficient mode of electronic cataloging for Web interface due to a better sense of presence of users, a more attractive and enjoyable media of delivery of useful information to users, and a higher level of engagement of user's memory. A 3-D VO, as a result, generates the highest users' satisfaction, which leads to increased propensity to purchase. Further, we discuss the practical and theoretical research implications of these findings to e-catalogs. © 2007 IEEE.published_or_final_versio

Modeling and analysis of supply chain risk system under the influence of partners' collaboration

Confining the focus to individual enterprise, traditional risk management literature seems to echo inadequately in the context of collaborative supply chain, partially due to its exclusion of correlation of risks across companies. In this study, we refine the notion of risk in supply chain and propose a model of supply chain risk system (SCRS) that consciously takes into account the correlation among risks resulting from partners' collaboration. Through analytical inference we found that the level of collaboration contributes to the resilience of supply chain. It implies that collaboration can positively affect the topology of SCRS, thus benefiting supply chain operations in terms of risk management. A simulation program has been developed with aim to demonstrate the practical feasibility of the proposed model. Implemented in simulation, two sets of experiments have been conducted for testing the model in actual business scenarios. The experimental results provide supporting evidence to consolidate the analytical findings. © 2011 IEEE.published_or_final_versionThe 44th Hawaii International Conference on System Science (HICSS 2011), Kauai, HI., 4-7 January 2011. In Proceedings of the Hawaii International Conference on System Sciences, 2011, p. 1-1

Design and evaluation of improvement method on the web information navigation - A stochastic search approach

With the advent of fast growing Internet and World Wide Web (the Web), more and more companies enhance the business competitiveness by conducting electronic commerce. At the same time, more and more people gather or process information by surfing on the Web. However, due to unbalanced Web traffic and poorly organized information, users suffer from slow communication and disordered information. To improve the situation, information providers can analyze the traffic and Uniform Resource Locator (URL) counters to adjust the information layering and organization; nevertheless, heterogeneous navigation patterns and dynamic fluctuating Web traffic complicate the improvement process. Alternatively, improvement can be made by giving direct guidance to the surfers in navigating the Web sites. In this paper, information retrieval on a Web site is modeled as a Markov chain associated with the corresponding dynamic Web traffic and designated information pages. We consider four models of information retrieval based on combination of the level of skill or experience of the surfers as well as the degree of navigation support by the sites. Simulation is conducted to evaluate the performance of the different types of navigation guidance. In addition, we evaluate the four models of information retrieval in terms of complexity and applicability. The paper concludes with a research summary and a direction for future research efforts. © 2009 Elsevier B.V. All rights reserved.postprin

E-procurement in public sector: a global overview

This paper provides a global overview of both recent developments and current initiatives in public e-procurement. The Hong Kong Government’s E-Procurement Pilot Programme will serve as a case study that will be discussed using a descriptive case study approach. A qualitative methodology is employed with findings that indicate that the development of public e-procurement is a matter of perception rather than other factors such as ITC infrastructure availability. E-procurement is underutilised in the public sector, where the majority of implemented systems are in the form of e-journal and e-tendering solutions. Concurrently, the findings also point to a growing trend in cross-border initiatives within public sectors where e-procurement is the driving force. The case study results suggest that the Hong Kong Government’s initiative is successful especially in terms of political support, adaptation of suppliers and system design. This paper provides valuable insight into the potential role of public e-procurement initiatives.postprin

Correlation between three assay systems for anti-Müllerian hormone (AMH) determination

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Forging a New World Order? Interdisciplinary Perspectives on the Management of Metalworking and Ideological Change in the Late Bronze Age Carpathian Basin

The Carpathian Basin was a highly influential centre of metalworking in the 2nd mil. BC. Nevertheless, despite the abundance of metal objects from the Late Bronze Age, the scarcity of contextually associated metalworking remains representing distinct phases of the metalworking cycle from this region is striking. Here, we explore Late Bronze Age metalworking through the lens of a uniquely complete metalworking assemblage from the site of Șagu from contexts spanning the sixteenth to early thirteenth century BC. This material provides insights into changes in craft organisation following socio-political change after the collapse of Middle Bronze Age tell-centred communities. Our approach combines analytical and experimental data together with contextual analysis of technical ceramics (crucible, mould, and furnace fragments) to reconstruct the metalworking chaîne opératoire and place Șagu in its broader cultural context. Analyses demonstrate clear technological choices in ceramic paste recipes and strong interlinkages between metallurgy and other crafts practised on site, from domestic pottery production to building structures. Experimental replications reveal important intrinsic and experiential aspects of metallurgical activities at Șagu. Evidence on the spatial organisation of metallurgical workflows (routine sequence of actions and decisions) suggests they incorporated a high degree of visibility, which marks a distinct change in the use of craft space compared to the context of densely occupied Middle Bronze Age tells nearby. Combined, our archaeometric, experimental, and contextual results illustrate how changes in metalworking activities in the Late Bronze Age Carpathian Basin were deeply embedded in an ideological shift in the aftermath of the breakdown of Middle Bronze Age tells and the emergence of new social structures

Symptomatology of carbamazepine- and oxcarbazepine-induced hyponatremia in people with epilepsy

OBJECTIVE: To ascertain whether adverse effects experienced by people taking carbamazepine or oxcarbazepine could be attributed to carbamazepine- or oxcarbazepine-induced hyponatremia (COIH). METHODS: We performed an observational study, collecting data between 2017 and 2019 on serum sodium levels and adverse effects retrospectively in people with epilepsy while receiving treatment with either carbamazepine (CBZ) or oxcarbazepine (OXC). We defined hyponatremia as sodium level ≤134 mEq/L and severe hyponatremia as sodium level ≤128 mEq/L. Adverse effects experienced were compared between groups of individuals with and without hyponatremia. RESULTS: A total of 1370 people using CBZ or OXC were identified, of whom 410 had at least one episode of hyponatremia. We checked for symptoms related to the use of CBZ and OXC in 710 people (410 with and 300 without hyponatremia) and found relevant information in 688. Adverse effects occurred in 65% of people with hyponatremia compared to 21% with normal sodium levels (odds ratio [OR] 7.5, P ≤ .001) and in 83% of people with severe hyponatremia compared to 55% in those with mild hyponatremia (P ≤ .001). Significant predictors of adverse effects were the drug (OXC vs CBZ), and the number of concomitant anti-seizure medications. Dizziness (28% vs 6%), tiredness (22% vs 7%), instability (19% vs 3%), and diplopia (16% vs 4%) were reported more often in the hyponatremia group than in patients with normal levels. SIGNIFICANCE: People with COIH had a 7-fold increased risk of developing adverse effects during treatment. Clinicians should consider ascertainment of sodium levels in patients taking CBZ and OXC and act upon findings

Emerging pharmacotherapy of tinnitus

Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life. Because tinnitus is frequently associated with irritability, agitation, stress, insomnia, anxiety and depression, the social and economic burdens of tinnitus can be enormous. No curative treatments are available. However, tinnitus symptoms can be alleviated to some extent. The most widespread management therapies consist of auditory stimulation and cognitive behavioral treatment, aiming at improving habituation and coping strategies. Available clinical trials vary in methodological rigor and have been performed for a considerable number of different drugs. None of the investigated drugs have demonstrated providing replicable long-term reduction of tinnitus impact in the majority of patients in excess of placebo effects. Accordingly, there are no FDA or European Medicines Agency approved drugs for the treatment of tinnitus. However, in spite of the lack of evidence, a large variety of different compounds are prescribed off-label. Therefore, more effective pharmacotherapies for this huge and still growing market are desperately needed and even a drug that produces only a small but significant effect would have an enormous therapeutic impact. This review describes current and emerging pharmacotherapies with current difficulties and limitations. In addition, it provides an estimate of the tinnitus market. Finally, it describes recent advances in the tinnitus field which may help overcome obstacles faced in the pharmacological treatment of tinnitus. These include incomplete knowledge of tinnitus pathophysiology, lack of well-established animal models, heterogeneity of different forms of tinnitus, difficulties in tinnitus assessment and outcome measurement and variability in clinical trial methodology. © 2009 Informa UK Ltd.Fil: Langguth, Berthold. Universitat Regensburg; AlemaniaFil: Salvi, Richard. State University of New York; Estados UnidosFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentin