2,196 research outputs found
A clinical algorithm for wound biofilm identication
Broj publiciranih referenci koje ukazuju na prisutnost biofi lma u kroniÄnim ranama je u porastu. Sve je veÄi broj dokaza koji potvrÄuju da biofilm znaÄajno sudjeluje u nezacijeljivanju rane i u bakterijskim infekcijama. Iz navedenih razloga postavlja se pitanje nedostatka postupnika o dokazima prisutnosti biofilma u rani. Namjera je ovog rada specifi cirati vidljive dokaze i indirektno dati kliniÄke smjernice tretmana biofilma u rani, te predloĆŸiti odreÄeni postupnik za olakĆĄanje kliniÄkog
prepoznavanja biofi lma da bi se potom promijenilo ciljano lijeÄenje vrijeda.Recognition of the existence of biofilm in chronic wounds is increasing among wound care practitioners, and a growing body of evidence indicates that biofilm contributes significantly to wound recalcitrance. While clinical guidelines regarding the involvement of biofilm in human bacterial infections have been proposed, there remains uncertainty and lack of guidance towards biofilm presence in wounds. The intention of this report is to collate knowledge and evidence of the visual and indirect clinical indicators of wound biofilm, and propose an algorithm designed to facilitate clinical recognition of biofilm and subsequent wound management practices
Doping nature of native defects in 1T-TiSe2
The transition metal dichalcogenide 1T-TiSe2 is a quasi two-dimensional
layered material with a charge density wave (CDW) transition temperature of
TCDW 200 K. Self-doping effects for crystals grown at different temperatures
introduce structural defects, modify the temperature dependent resistivity and
strongly perturbate the CDW phase. Here we study the structural and doping
nature of such native defects combining scanning tunneling
microscopy/spectroscopy and ab initio calculations. The dominant native single
atom dopants we identify in our single crystals are intercalated Ti atoms, Se
vacancies and Se substitutions by residual iodine and oxygen.Comment: 5 pages, 3 figure
STM microscopy of the CDW in 1T-TiSe2 in the presence of single atom defects
We present a detailed low temperature scanning tunneling microscopy study of
the commensurate charge density wave (CDW) in 1-TiSe in the presence of
single atom defects. We find no significant modification of the CDW lattice in
single crystals with native defects concentrations where some bulk probes
already measure substantial reductions in the CDW phase transition signature.
Systematic analysis of STM micrographs combined with density functional theory
modelling of atomic defect patterns indicate that the observed CDW modulation
lies in the Se surface layer. The defect patterns clearly show there are no
2-polytype inclusions in the CDW phase, as previously found at room
temperature [Titov A.N. et al, Phys. Sol. State 53, 1073 (2011). They further
provide an alternative explanation for the chiral Friedel oscillations recently
reported in this compound [J. Ishioka et al., Phys. Rev. B 84, 245125, (2011)].Comment: 5 pages, 4 figure
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Understanding the Mind or Predicting Signal-Dependent Action? Performance of Children With and Without Autism on Analogues of the False-Belief Task
To evaluate the claim that correct performance on unexpected transfer false-belief tasks specifically involves mental-state understanding, two experiments were carried out with children with autism, intellectual disabilities, and typical development. In both experiments, children were given a standard unexpected transfer false-belief task and a mental-state-free, mechanical analogue task in which participants had to predict the destination of a train based on true or false signal information. In both experiments, performance on the mechanical task was found to correlate with that on the false-belief task for all groups of children. Logistic regression showed that performance on the mechanical analogue significantly predicted performance on the false-belief task even after accounting for the effects of verbal mental age. The findings are discussed in relation to possible common mechanisms underlying correct performance on the two tasks
Memory, learning and language in autism spectrum disorder
Background and aims: The âdual-systemsâ model of language acquisition has been used by Ullman and colleagues to explain patterns of strength and weakness in the language of higher-functioning people with autism spectrum disorder (ASD). Specifically, intact declarative/explicit learning is argued to compensate for a deficit in non-declarative/implicit procedural learning, constituting an example of the so-called âsee-sawâ effect. Ullman and Pullman (2015) extended their argument concerning a see-saw effect on language in ASD to cover other perceived anomalies of behaviour, including impaired acquisition of social skills. The aim of this paper is to present a critique of Ullman and colleaguesâ claims, and to propose an alternative model of links between memory systems and language in ASD.
Main contribution: We argue that a 4-systems model of learning, in which intact semantic and procedural memory are used to compensate for weaknesses in episodic memory and perceptual learning, can better explain patterns of language ability across the autistic spectrum. We also argue that attempts to generalise the âimpaired implicit learning/spared declarative learningâ theory to other behaviours in ASD are unsustainable.
Conclusions: Clinically significant language impairments in ASD are under-researched, despite their impact on everyday functioning and quality of life. The relative paucity of research findings in this area lays it open to speculative interpretation which may be misleading.
Implications: More research is need into links between memory/learning systems and language impairments across the spectrum. Improved understanding should inform therapeutic intervention, and contribute to investigation of the causes of language impairment in ASD with potential implications for prevention
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Different Verbal Learning Strategies in Autism Spectrum Disorder: Evidence from the Rey Auditory Verbal Learning Test
The Rey Auditory Verbal Learning Test, which requires the free recall of the same list of 15 items over 5 trials, was administered to a group of highfunctioning adolescents and adults with autism spectrum disorder (PDD) and a group of matched typical individuals. Overall levels of free recall were comparable in the two groups, as were the rates of learning over trials. Both groups also subjectively organised their recall to a similar extent. However, the serial position curve of the PDD participants, although similar to that of the comparison group on the first trial, became flatter on subsequent trials and was characterised by a slower growth in the primacy effect. Growth in the middle and recency portions of the curve was comparable in both groups. The findings are discussed in the light of current models of serial position effects and their implications for memory in ASD
ALMA Observations of the Young Substellar Binary System 2M1207
We present ALMA observations of the 2M1207 system, a young binary made of a
brown dwarf with a planetary-mass companion at a projected separation of about
40 au. We detect emission from dust continuum at 0.89 mm and from the rotational transition of CO from a very compact disk around the young brown
dwarf. The small radius found for this brown dwarf disk may be due to
truncation from the tidal interaction with the planetary-mass companion. Under
the assumption of optically thin dust emission, we estimated a dust mass of 0.1
for the 2M1207A disk, and a 3 upper limit of for dust surrounding 2M1207b, which is the tightest upper
limit obtained so far for the mass of dust particles surrounding a young
planetary-mass companion. We discuss the impact of this and other
non-detections of young planetary-mass companions for models of planet
formation, which predict the presence of circum-planetary material surrounding
these objects.Comment: 10 pages, 6 figures, accepted for publication in A
Jet velocity in SS433: its anti-correlation with precession-cone angle and dependence on orbital phase
We present a re-analysis of the optical spectroscopic data on SS433 from the
last quarter-century and demonstrate that these data alone contain systematic
and identifiable deviations from the traditional kinematic model for the jets:
variations in speed, which agree with our analysis of recent radio data; in
precession-cone angle and in phase. We present a simple technique for
separating out the jet speed from the angular properties of the jet axis,
assuming only that the jets are symmetric. With this technique, the archival
optical data reveal that the variations in jet speed and in precession-cone
angle are anti-correlated in the sense that when faster jet bolides are ejected
the cone opening angle is smaller. We also find speed oscillations as a
function of orbital phase.Comment: accepted by ApJ Letter
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