166 research outputs found

    Effects of Occupational Therapy on Hospitalized Chronic Schizophrenia Patients with Severe Negative Symptoms

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    The aim of this study was to determine whether occupational therapy (OT) can improve the interpersonal relationships and negative symptoms of hospitalized chronic schizophrenia patients with severe negative symptoms. Subjects were 38 patients with chronic schizophrenia. They were randomly divided into an OT group and a control group. Patients in the OT group participated in cooking activities once a week for 15 weeks, while patients in the control group did not. During this period, both groups had the usual treatment except for the cooking activities. In interviews, the patient was asked to place a chair toward the interviewer (a therapist). The angle and distance from the interviewer were taken as indicators of an ability to have interpersonal relationships. Negative symptoms were evaluated with the Scale for the Assessment of Negative Symptoms (SANS). Patients who received OT were able to sit at the smaller angle and shorter distance from the interviewer than before OT (p=0.015 and p=0.013, respectively). The total SANS score was lower after OT than before OT (p=0.033). In the control group, the distance from the interviewer also decreased during the experimental period (p=0.040) but the seating angle and the SANS scores did not change. The results suggest that OT can help to improve a relationship allowing the patient to face the therapist and that it might improve negative symptoms of schizophrenia

    Effects of Medication Review on Drug-Related Problems in Patients Using Automated Drug-Dispensing Systems A Pragmatic Randomized Controlled Study

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    Public Health and primary careGeriatrics in primary car

    Супутні зміни рівнів в плазмі стероїдних гормонів за різних варіантів впливу бальнеотерапії на курорті Трускавець на рівень тестостерону у жінок

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    В клинико-физиологическом наблюдении за 100 женщинами 20-40 лет с сочетанной хронической патологией пищеварительной и репродуктивной систем изучено влияние курса стандартной бальнеотерапии на курорте Трускавец на сопутствующие изменения содержания в плазме стероидных гормонов эстрадиола, прогестерона, кортизола и альдостерона при различных начальных уровнях тестостерона. Выявлены тесные прямые корреляционные связи между тестостеронемией и содержанием в плазме эстрадиола и кортизола и умеренные - с прогестеронемией (прямую) и альдостероном (обратную). Динамика тестостеронемии под влиянием бальнеотерапии тесно прямо коррелирует с изменениями уровней кортизола и эстрадиола и умеренно инверсно - с динамикой альдостерона, тогда как с динамикой прогестерона связь имеет нелинейный характер.In the clinical physiological looking after 100 women 20-40 years with combinative chronic pathology of the digestive and genesial systems is studied influence of course of standard balneotherapy on spa Truskavets on the concomitant changes of maintenance in plasma of steroide hormones estradiol, progesterone, cortisol and aldosterone at the different initial levels of testosterone. Close lines are exposed cross-correlation connections between testosterone and maintenance in plasma of estradiol and cortisol and moderate - with progesterone (line) and aldosterone (reverse). Dynamics of testosterone under influence of balneotherapy closely straight correlates with the changes of levels of cortisol and estradiol and mildly inversely - with the dynamics of aldosterone, while with the dynamics of progesterone connection has nonlinear character

    Patterns of recurring dispensing of guideline antibiotics for uncomplicated urinary tract infection in women over a 5-year period: longitudinal patterns of recurring dispensings of Dutch guideline UTI antibiotics

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    Background. Urinary tract infection (UTI) is one of the most prevalent medical conditions among women seeking primary care. About 20-40% of the women have a UTI recurrence during their lifetime.Objective. To provide insight in the patterns of recurring annual dispensing for antibiotics commonly used for UTI treatment in women, aged 18 years or older, during a 5-year follow-up period in the Netherlands.Methods. The Dutch Foundation of Pharmaceutical statistics collects dispensing data from more than 90% of all community pharmacies. Pharmacies with complete data between years 2011 and 2017 were included. Women of age 18 years or older with a first dispensing of nitrofurantoin, fosfomycin, or trimethoprim in 2012 and a dispensing of any medication in 2017 were selected. For each year between 2013 and 2017, the proportions of women with recurring dispensing of nitrofurantoin, fosfomycin or trimethoprim were calculated and stratified for age categories.Results. Within 1517 eligible community pharmacies, 463 821 women, aged 18 years or older, were dispensed one of the antibiotics in 2012, and 239 292 women still visited the same pharmacy in 2017. About 56% of them received at least one recurring dispensing during 5 years of follow-up. Each year, similar to 20% of the source population had at least one recurring dispensing. Approximately 2% of the source population had at least one recurring dispensing in each year of follow-up.Conclusions. Over the 5-year study period, more than 50% of the source population had at least one recurring dispensing for uncomplicated UTI, most of them with at least 1 year without UTI dispensing in between.Clinical Pharmacy and Toxicolog
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