4 research outputs found

    Troubles du sommeil chez le sujet ùgé en institutions gériatriques

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    Cette Ă©tude avait pour but de faire un Ă©tat des lieux en institutions gĂ©riatriques. Elle cherchait Ă  dĂ©montrer l'importance des facteurs environnementaux et mĂ©dicamenteux. Dans un 1er temps, on s'est attachĂ© Ă  faire un rappel des donnĂ©es biologiques du sommeil chez le sujet ĂągĂ© puis un tour d'horizon des pathologies du sommeil du sujet ĂągĂ©. L'Ă©tude elle mĂȘme repose sur 3 questionnaires distribuĂ©s aux rĂ©sidents, aux soignants (A. soignants et I.D.E.) et aux mĂ©decins. Malheureusement, les questionnaires se sont montrĂ©s par trop ambitieux. Il en ressort nĂ©anmoins quelques points dont un important rejoignant les recommandations de la Haute AutoritĂ© de SantĂ©. Les soignants et les mĂ©decins souhaitent aussi bĂ©nĂ©ficier d'une formation spĂ©cifique du sommeil de l'ĂągĂ©.CLERMONT FD-BCIU-SantĂ© (631132104) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

    Occult maternal exposure to environmental tobacco smoke exposure

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    International audienceBackground: Environmental tobacco smoke (ETS) is a recognised air pollutant. Its harmful effects have been found to be implicated in health disorders, including unfavourable pregnancy outcomes. The discrepancy between self-reported emvironmental tobacco smoke exposure and cotinine levels in pregnant non-smokers in France was examined.Method: Plasma cotinine was determined by a CPG-SM method on women who had answered a self-questionnaire describing their habits and environment during pregnancy.Results: Of 698 pregnant women reported as non-smokers, 305 (43.7%) claimed not to be exposed to ETS, yet 196 of these (64.3%) had plasma cotinine levels above the limit of detection.Conclusion: Self-reported data on ETS exposure in pregnant women therefore underestimate actual exposure. However, cotinine assay cab rectify this misclassification. An accurate identification of this risk factore will help to change attitudes towards ETS and avert its adverse effects on mother and fetus

    Limits of usual biochemical alcohol markers in cord blood at term: A fetal/maternal population-based study

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    Background: After maternal alcohol consumption during pregnancy, many neonates affected by less apparent forms of fetal alcohol syndrome disorder (FASD) do not receive proper diagnosis or treatment. There is thus a need for laboratory markers for early detection of alcohol-exposed neonates. The aim of our study was to assess the efficiency of the usual alcohol biomarkers measured in cord blood to identify alcohol-exposed neonates immediately after birth. Methods: A 1-year study was conducted in the labor wards of the maternity units of the Auvergne, Central France at the time of term delivery. The patients answered an anonymous self-completion survey concerning alcohol use (Alcohol Use Disorder Identification Test; AUDIT) during their pregnancy. Aspartate aminotransferase, alanine aminotransferase, and γ-glutamyltransferase concentrations and the percentage of carbohydrate-deficient transferrin were measured in maternal and cord blood. Results: We collected 870 maternal-fetal sample pairs. Two cases (0.2%) of typical FASD were detected. We report a non-significant correlation between maternal and cord blood biomarkers. None of the cord blood biomarkers differed significantly between newborns of alcohol-exposed and unexposed mothers. Conclusions: We demonstrate that the usual alcohol biomarkers are not effective in cord blood for identifying alcohol-exposed neonates. ©2007 by Walter de Gruyter.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Psychiatric symptoms and mortality in older adults with major psychiatric disorders: results from a multicenter study

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    International audienc
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