A Next-to-Leading-Order Study of Dihadron Production

The production of pairs of hadrons in hadronic collisions is studied using a next-to-leading-order Monte Carlo program based on the phase space slicing technique. Up-to-date fragmentation functions based on fits to LEP data are employed, together with several versions of current parton distribution functions. Good agreement is found with data for the dihadron mass distribution. A comparison is also made with data for the dihadron angular distribution. The scale dependence of the predictions and the dependence on the choices made for the fragmentation and parton distribution functions are also presented. The good agreement between theory and experiment is contrasted to the case for single $\pi^0$ production where significant deviations between theory and experiment have been observed.Comment: 22 pages, 15 figures; 3 references added, one figure modified for clarit

Relationship between pneumonitis induced by immune checkpoint inhibitors and the underlying parenchymal status: a retrospective study.

In patients with primary or secondary lung tumour treated with immune checkpoint inhibitors, immune-related pneumonitis is a rare adverse event but may evolve to respiratory failure. Prompt management is required and usually consists of treatment interruption and immunosuppressive drug administration. The aim of this study was to evaluate relationships between immune-related pneumonitis and pre-existing parenchymal status, especially tumour location and history of chest radiotherapy. Computed tomography (CT) scans of patients with immune-related pneumonitis were retrospectively reviewed. Pattern, distribution and extent of pneumonitis were assessed in six lung regions. In patients who received radiotherapy, the extent of pneumonitis was evaluated according to the radiation field. Among 253 patients treated with immunotherapy, 15 cases of immune-related pneumonitis were identified. 10 had previous or concomitant chest radiotherapy in addition to immunotherapy. At CT scan, 29 (33%) out of 88 regions encompassed the primary tumour (n=4), a lung metastasis (n=4) and/or radiation fields (n=21). A significantly higher prevalence of parenchymal involvement by immune-related pneumonitis occurred within areas of primary or metastatic malignancy and/or radiation field (97%) as compared to other areas (3%, p=0.009). Lung regions affected by the primary tumour, metastasis or radiotherapy had a higher probability of immune-related pneumonitis than others (OR 10.8, p=0.024). An organising pneumonia (OP) pattern was more frequent after radiotherapy (70% versus 0%, p=0.024), whereas nonspecific interstitial pneumonia features were more commonly seen in radiotherapy-naive patients (100% versus 10%, p=0.002). In patients with primary or secondary lung tumour treated with immune checkpoint inhibitors, immune-related pneumonitis is preferentially located within lung areas involved by tumour and/or radiation fields

Abscopal effect in a patient with malignant pleural mesothelioma treated with palliative radiotherapy and pembrolizumab.

The abscopal effect describes the ability of locally administered radiotherapy to induce systemic antitumor effects. Although mentioned for the first time in the 1950s, records of abscopal effects, considered to be immune-mediated, are scarce with radiotherapy alone. However, with the continued development and use of immunotherapy, reports on the abscopal effect have become increasingly frequent during the last decade. Here, we report a patient with advanced malignant pleural mesothelioma who had progressive disease while on the anti-PDL1 inhibitor pembrolizumab and showed an abscopal response after palliative radiotherapy

Virtual photon fragmentation functions

We introduce operator definitions for virtual photon fragmentation functions, which are needed for reliable calculations of Drell-Yan transverse momentum ($Q_T$) distributions when $Q_T$ is much larger than the invariant mass $Q$. We derive the evolution equations for these fragmentation functions. We calculate the leading order evolution kernels for partons to fragment into a unpolarized as well as a polarized virtual photon. We find that fragmentation functions to a longitudinally polarized virtual photon are most important at small $z$, and the fragmentation functions to a transversely polarized virtual photon dominate the large $z$ region. We discuss the implications of this finding to the J/$\psi$ mesons' polarization at large transverse momentum.Comment: Latex, 19 pages including 6 figures. An error in the first version has been corrected, and references update

Vitality, Language Use, and Life Satisfaction : A Study of Bilingual Hungarian Adolescents Living in Romania

This study examined the relationship between objective and subjective vitality, in-group language use, and life satisfaction among two groups of bilingual Hungarians adolescents living in Romania: a low objective vitality group from Cluj-Napoca/Kolozsvar, where Hungarians are the demographic minority, and a high objective vitality group from Sfantu Gheorghe/Sepsiszentgyorgy, where Hungarians are the demographic majority. Consistent with predictions, the high objective vitality group reported higher subjective Hungarian vitality, lower subjective Romanian vitality, more frequent use of the Hungarian language, and higher life satisfaction, compared with the low objective vitality group. The effects of objective vitality on language use were partially mediated by subjective Romanian (but not Hungarian) vitality. Conversely, the effects of objective vitality on life satisfaction were fully mediated by subjective Hungarian (but not Romanian) vitality.Peer reviewe

Investigating the high energy QCD approaches for prompt photon production at the LHC

We investigate the rapidity and transverse momentum distributions of the prompt photon production at the CERN LHC energies considering the current perturbative QCD approaches for this scattering process. Namely, we compare the predictions from the usual NLO pQCD calculations to the the color dipole formalism, using distinct dipole cross sections. Special attention is paid to parton saturation models at high energies, which are expected to be important at the forward rapidities in pp collisions at the LHC.Comment: Contribution to the proceedings of the 3rd International Conference on Hard and Electro-Magnetic Probes of High-Energy Nuclear Collisions (Hard Probes 2008), 8-14 June 2008, Illa da Toxa (Galicia-Spain). Talk presented by M.V.T. Machad

Colour-Octet Effects in Radiative Υ\Upsilon Decays

We investigate the effects of colour-octet contributions to the radiative $\Upsilon$ decay within the Bodwin, Braaten and Lepage NRQCD factorization framework. Photons coming both from the coupling to hard processes (`direct') and by collinear emission from light quarks (`fragmentation') are consistently included at next-to-leading order (NLO) in $\alpha_s$. An estimate for the non-perturbative matrix elements which enter in the final result is then obtained. By comparing the NRQCD prediction at NLO for total decay rates with the experimental data, it is found that the non-perturbative parameters must be smaller than expected from the na\"\i ve scaling rules of NRQCD. Nevertheless, colour-octet contributions to the shape of the photon spectrum turn out to be significant.Comment: 25 pages, Latex, 8 figure

Factorization and soft-gluon divergences in isolated-photon cross sections

We study the production of isolated photons in $e^+e^-$ annihilation and give the proof of the all-order factorization of the collinear singularities. These singularities are absorbed in the standard fragmentation functions of partons into a photon, while the effects of the isolation are consistently included in the short-distance cross section. We compute this cross section at order \as and show that it contains large double logarithms of the isolation parameters. We explain the physical origin of these logarithms and discuss the possibility to resum them to all orders in \as.Comment: 18 pages, LaTex, 2 eps figures, few modifications in the text, results unchange

Kinematic Effects in Radiative Quarkonia Decays

Non-relativistic QCD (NRQCD) predicts colour octet contributions to be significant not only in many production processes of heavy quarkonia but also in their radiative decays. We investigate the photon energy distributions in these processes in the endpoint region. There the velocity expansion of NRQCD breaks down which requires a resummation of an infinite class of colour octet operators to so-called shape functions. We model these non-perturbative functions by the emission of a soft gluon cluster in the initial state. We found that the spectrum in the endpoint region is poorly understood if the values for the colour octet matrix elements are taken as large as indicated from NRQCD scaling rules. Therefore the endpoint region should not be taken into account for a fit of the strong coupling constant at the scale of the heavy quark mass.Comment: LaTeX, 17 pages, 5 figures. The complete paper is also available via the www at http://www-ttp.physik.uni-karlsruhe.de/Preprints

Accessing transversity with interference fragmentation functions

We discuss in detail the option to access the transversity distribution function $h_1(x)$ by utilizing the analyzing power of interference fragmentation functions in two-pion production inside the same current jet. The transverse polarization of the fragmenting quark is related to the transverse component of the relative momentum of the hadron pair via a new azimuthal angle. As a specific example, we spell out thoroughly the way to extract $h_1(x)$ from a measured single spin asymmetry in two-pion inclusive lepton-nucleon scattering. To estimate the sizes of observable effects we employ a spectator model for the fragmentation functions. The resulting asymmetry of our example is discussed as arising in different scenarios for the transversity.Comment: 17 pages, 15 figures in .eps format included, typesetted in RevTeX and epsfig.sty, submitted to Phys. Rev.