190 research outputs found

    What If We Get Open Access?: A New Case for Undergraduate Scientific Literacy

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    For the educators among us who care about the Open Access Movement, are we prepared for what comes in a post-OA world? Suppose that Plan-S (or another initiative with similar objectives) succeeds in making vast quantities of previously paywalled scientific literature openly available to anyone with an Internet connection. On one hand, it\u27s the utopia we\u27ve fought for: our best ideas, set free to circulate among the minds who will incorporate them toward solving the big issues humanity faces. On the other hand, what if scientific literature becomes weaponized in the same way that journalism has in recent years, where legitimate work gets sewn with seeds of doubt, and bad-faith efforts gain more traction than they deserve. When our research institutions continue to have trouble assessing science literature, to what measure should laypersons hold themselves? In this cheery presentation, we will imagine a possible dystopia of our own creation, followed by a discussion of tools, tech, and approaches that could be used in an undergraduate education setting to make our future scientists better research communicators and our future citizens better research consumers

    The AGATA Spectrometer

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    Abstract The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate a high-resolution gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. The tracking technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. AGATA can measure gamma rays from 10’s of keV to 10 MeV with excellent efficiency and position resolution and has a very high count rate capability. The realisation of AGATA and gamma-ray tracking is a result of many technical advances. AGATA has operated in a series of successful scientific campaigns at Legnaro National Laboratory in Italy, GSI in Germany and GANIL in France. AGATA is now in its next phase of development as it evolves to the full 4π instrument. It is presently starting its next campaign at Legnaro.</jats:p

    Open Educational Resources in Kentucky

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    Open educational resources (OER) play an increasingly important role in the education landscape, with increased awareness and use year over year (Coffey). Often, academic libraries play a supporting role for instructors as they locate, adopt, and create OER for their courses. In this article, we will provide an introduction to OER, outline some current trends in open education, and describe a few of the OER initiatives currently underway in Kentucky’s college and university libraries

    Progress towards a semiconductor Compton camera for prompt gamma imaging during proton beam therapy for range and dose verification

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    The main objective of this work is to test a new semiconductor Compton camera for prompt gamma imaging. Our device is composed of three active layers: a Si(Li) detector as a scatterer and two high purity Germanium detectors as absorbers of high-energy gamma rays. We performed Monte Carlo simulations using the Geant4 toolkit to characterise the expected gamma field during proton beam therapy and have made experimental measurements of the gamma spectrum with a 60 MeV passive scattering beam irradiating a phantom. In this proceeding, we describe the status of the Compton camera and present the first preliminary measurements with radioactive sources and their corresponding reconstructed images

    Characterisation of a small electrode HPGe detector

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    © 2019 Elsevier B.V. Small electrode HPGe detectors in an inverted coaxial geometry are increasingly in use in applications where both high efficiency and excellent energy resolution are required. The unusual electric field configuration of these detectors results in extremely long charge collection times compared to planar and coaxial devices. In this work we have characterised such a detector using gamma-ray coincidence measurements and optimised an electric field simulation to reproduce the positional variation of detector response. We show that, alongside accurate crystal geometry and applied electric potential, a temperature correction is crucial to correctly determining appropriate charge carrier mobility parameters. This work will help to guide the future development of HPGE detectors for applications including radioactive waste assay, radio-isotope dating, and fundamental nuclear physics

    Thermotolerance and molecular chaperone function of the small heat shock protein HSP20 from hyperthermophilic archaeon, Sulfolobus solfataricus P2

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    Small heat shock proteins are ubiquitous in all three domains (Archaea, Bacteria and Eukarya) and possess molecular chaperone activity by binding to unfolded polypeptides and preventing aggregation of proteins in vitro. The functions of a small heat shock protein (S.so-HSP20) from the hyperthermophilic archaeon, Sulfolobus solfataricus P2 have not been described. In the present study, we used real-time polymerase chain reaction analysis to measure mRNA expression of S.so-HSP20 in S. solfataricus P2 and found that it was induced by temperatures that were substantially lower (60°C) or higher (80°C) than the optimal temperature for S. solfataricus P2 (75°C). The expression of S.so-HSP20 mRNA was also up-regulated by cold shock (4°C). Escherichia coli cells expressing S.so-HSP20 showed greater thermotolerance in response to temperature shock (50°C, 4°C). By assaying enzyme activities, S.so-HSP20 was found to promote the proper folding of thermo-denatured citrate synthase and insulin B chain. These results suggest that S.so-HSP20 promotes thermotolerance and engages in chaperone-like activity during the stress response
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