Actividad fisica para el incremento de la fase de velocidad en los estudiantes del 1er año de secundaria de la I.E.E. Melchor Aponte del distrito de Vegueta 2020

La presente investigación tiene por objetivo Determinar la relación que existe entre actividad física para el incremento de la fase de velocidad en los estudiantes del 1er año de secundaria de la I.E.E. Melchor aponte del distrito de Vegueta 2020. Se determinó como variable: actividad física y fases de velocidad en los estudiantes del 1er año de secundaria. La investigación es de tipo básica cuantitativa y de diseño no experimental descriptivo correlacional. En la investigación se ha contabilizado una población de100 alumnos del 1er año de secundaria de la I.E.E. Melchor aponte. . Los resultados del proyecto indicaran el grado correlación de r= 0.930, con una p=0.000 (p<0.05) en el que se aceptara la hipótesis alternativa general del proyecto y de este modo se va rechazar la hipótesis nula, por lo cual se evidencia mediante la estadística que existe relación significativa de una magnitud muy alta entre actividad física y fases de velocidad en los estudiantes del 1er año de secundaria de la I.E.E. Melchor aponte del distrito de Vegueta 202

Conquista y administración romana de las provincias hispánicas en época republicana. Bronces de Lascuta, Alcántara y Botorrita.

La llegada de los romanos a la península ibérica produce unos primeros siglos de conquista y desarrollo de la administración. Este proceso se encuentra ubicado en la República romana siendo un periodo de constante expansión, guerras y cambios en la política romana. El objetivo de este trabajo es conocer la administración de los nuevas provincias hispánicas conquistadas. El análisis ha sido posible gracias a tres piezas de epigrafía latina en bronce que muestran de la administración de estos territorios

Pesticide Exposure Alters Follicle-Stimulating Hormone Levels in Mexican Agricultural Workers

Organophosphorous pesticides (OPs) are suspected of altering reproductive function by reducing brain acetylcholinesterase activity and monoamine levels, thus impairing hypothalamic and/or pituitary endocrine functions and gonadal processes. Our objective was to evaluate in a longitudinal study the association between OP exposure and serum levels of pituitary and sex hormones. Urinary OP metabolite levels were measured by gas–liquid chromatography, and serum pituitary and sex hormone levels by enzymatic immunoassay and radioimmunoassay in 64 men. A total of 147 urine and blood samples were analyzed for each parameter. More than 80% of the participants had at least one OP metabolite in their urine samples. The most frequent metabolite found was diethylthiophosphate (DETP; 55%), followed by diethylphosphate (DEP; 46%), dimethylthiophosphate (DMTP; 32%), and dimethyldithiophosphate (DMDTP; 31%). However, the metabolites detected at higher concentrations were DMTP, DEP, DMDTP, and dimethylphosphate. There was a high proportion of individuals with follicle-stimulating hormone (FSH) concentrations outside the range of normality (48%). The average FSH serum levels were higher during the heavy pesticide spraying season. However, a multivariate analysis of data collected in all periods showed that serum FSH levels were negatively associated with urinary concentrations of both DMTP and DMDTP, whereas luteinizing hormone (LH) was negatively associated with DMTP. We observed no significant associations between estradiol or testosterone serum levels with OP metabolites. The hormonal disruption in agricultural workers presented here, together with results from experimental animal studies, suggests that OP exposure disrupts the hypothalamic–pituitary endocrine function and also indicates that FSH and LH are the hormones most affected

Substantial morbidity and mortality associated with pandemic A/H1N1 influenza in Mexico, winter 2013-2014: Gradual age shift and severity.

BACKGROUND: A recrudescent wave of pandemic influenza A/H1N1 is underway in Mexico in winter 2013-14, following a mild 2012-13 A/H3N2 influenza season. Mexico previously experienced several waves of pandemic A/H1N1 activity in spring, summer and fall 2009 and winter 2011-2012, with a gradual shift of influenza-related hospitalizations and deaths towards older ages. Here we describe changes in the epidemiology of the 2013-14 A/H1N1 influenza outbreak, relative to previous seasons dominated by the A/H1N1 pandemic virus. The analysis is intended to guide public health intervention strategies in near real time. METHODS: We analyzed demographic and geographic data on hospitalizations with severe acute respiratory infection (SARI), laboratory-confirmed A/H1N1 influenza hospitalizations, and inpatient deaths, from a large prospective surveillance system maintained by the Mexican Social Security medical system during 01-October 2013 to 31-Jan 2014. We characterized the age and regional patterns of influenza activity relative to the preceding 2011-2012 A/H1N1 influenza epidemic. We also estimated the reproduction number (R) based on the growth rate of daily case incidence by date of symptoms onset. RESULTS: A total of 7,886 SARI hospitalizations and 529 inpatient-deaths (3.2%) were reported between 01-October 2013 and 31-January 2014 (resulting in 3.2 laboratory-confirmed A/H1N1 hospitalizations per 100,00 and 0.52 laboratory-confirmed A/H1N1-positive deaths per 100,000). The progression of daily SARI hospitalizations in 2013-14 exceeded that observed during the 2011-2012 A/H1N1 epidemic. The mean age of laboratory-confirmed A/H1N1 patients in 2013-14 was 41.1 y (SD=20.3) for hospitalizations and 49.2 y (SD=16.7) for deaths. Rates of laboratory-confirmed A/H1N1 hospitalizations and deaths were significantly higher among individuals aged 30-59 y and lower among younger age groups for the ongoing 2013-2014 epidemic, compared to the 2011-12 A/H1N1 epidemic (Chi-square test, P\u3c0.001). The reproduction number of the winter 2013-14 wave in central Mexico was estimated at 1.3-1.4 which is slightly higher than that reported for the 2011-2012 A/H1N1 epidemic. CONCLUSIONS: We have documented a substantial and ongoing increase in the number of A/H1N1-related hospitalizations and deaths during the period October 2013-January 2014 and a proportionate shift of severe disease to middle aged adults, relative to the preceding A/H1N1 2011-2012 epidemic in Mexico. In the absence of clear antigenic drift in globally circulating A/H1N1 viruses in the post-pandemic period, the gradual change in the age distribution of A/H1N1 infections observed in Mexico suggests a slow build-up of immunity among younger populations, reminiscent of the age profile of past pandemics

SkyCDS: A resilient content delivery service based on diversified cloud storage

Cloud-based storage is a popular outsourcing solution for organizations to deliver contents to end-users. However, there is a need for contingency plans to ensure service provision when the provider either suffers outages or is going out of business. This paper presents SkyCDS: a resilient content delivery service based on a publish/subscribe overlay over diversified cloud storage. SkyCDS splits the content delivery into metadata and content storage flow layers. The metadata flow layer is based on publish-subscribe patterns for insourcing the metadata control back to content owner. The storage layer is based on dispersal information over multiple cloud locations with which organizations outsource content storage in a controlled manner. In SkyCDS, the content dispersion is performed on the publisher side and the content retrieving process on the end-user side (the subscriber), which reduces the load on the organization side only to metadata management. SkyCDS also lowers the overhead of the content dispersion and retrieving processes by taking advantage of multi-core technology. A new allocation strategy based on cloud storage diversification and failure masking mechanisms minimize side effects of temporary, permanent cloud-based service outages and vendor lock-in. We developed a SkyCDS prototype that was evaluated by using synthetic workloads and a study case with real traces. Publish/subscribe queuing patterns were evaluated by using a simulation tool based on characterized metrics taken from experimental evaluation. The evaluation revealed the feasibility of SkyCDS in terms of performance, reliability and storage space profitability. It also shows a novel way to compare the storage/delivery options through risk assessment. (C) 2015 Elsevier B.V. All rights reserved.The work presented in this paper has been partially supported by EU under the COST programme Action IC1305, Network for Sustainable Ultrascale Computing (NESUS)

Reproductive effects of occupational DDT exposure among male malaria control workers.

To assess potential effects of human DDT [1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane] exposure, we evaluated the reproductive history of 2,033 workers in the antimalaria campaign of Mexico. Data on occupational exposure to DDT and reproductive outcomes were gathered through a questionnaire, and workers provided information about 9,187 pregnancies. We estimated paternal exposure to DDT before each pregnancy using three approaches: a) a dichotomous indicator for pregnancies before and after exposure began, b) a qualitative index of four exposure categories, and c) an estimation of the DDT metabolite DDE [1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene] accumulated in fat. To assess associations, we used logistic regression models that accounted for correlated observations and adjusted for parents' age at each child's birth, exposure to other pesticides, exposure to chemical substances in other employment, smoking, and alcohol consumption. The odds ratio for birth defects comparing pregnancies after and before the first exposure was 3.77 [95% confidence interval (95% CI), 1.19-9.52]. Compared with the lowest quartile of estimated DDE in fat, the ORs were 2.48 (95% CI, 0.75-8.11), 4.15 (95% CI, 1.38-12.46), and 3.76 (95% CI, 1.23-11.44) for quartiles 2, 3, and 4, equivalent to p,p -DDE in fat of 50, 82, and 298 microg/g fat, respectively. No significant association was found for spontaneous abortion or sex ratio. We found an increased risk of birth defects associated with high occupational exposure to DDT in this group of workers. The significance of this association at lower exposure levels found in the general population remains uncertain

Lenguajes de Patrones de Arquitectura de Software: Una Aproximación Al Estado del Arte

El propósito principal del presente trabajo es  mostrar el estado del arte en investigación del área de la Arquitectura de Software conocida como “Lenguajes de Patrones”. Partiendo de sus orígenes, llegando hasta los avances actuales y analizando su aplicación en la construcción de arquitecturas de software para diversos sistemas de información en dominios específicos. Este último aspecto es de gran importancia, ya que como se verá más adelante en este artículo, la extensibilidad y aplicabilidad de los Lenguajes de Patrones, se convierte en una herramienta importante para diseñadores e implementadores  de todo tipo de sistemas de informació

Lenguajes de Patrones de Arquitectura de Software: Una Aproximación Al Estado del Arte

El propósito principal del presente trabajo es  mostrar el estado del arte en investigación del área de la Arquitectura de Software conocida como “Lenguajes de Patrones”. Partiendo de sus orígenes, llegando hasta los avances actuales y analizando su aplicación en la construcción de arquitecturas de software para diversos sistemas de información en dominios específicos. Este último aspecto es de gran importancia, ya que como se verá más adelante en este artículo, la extensibilidad y aplicabilidad de los Lenguajes de Patrones, se convierte en una herramienta importante para diseñadores e implementadores  de todo tipo de sistemas de informació

Lenguajes de Patrones de Arquitectura de Software: Una Aproximación Al Estado del Arte

El propósito principal del presente trabajo es  mostrar el estado del arte en investigación del área de la Arquitectura de Software conocida como “Lenguajes de Patrones”. Partiendo de sus orígenes, llegando hasta los avances actuales y analizando su aplicación en la construcción de arquitecturas de software para diversos sistemas de información en dominios específicos. Este último aspecto es de gran importancia, ya que como se verá más adelante en este artículo, la extensibilidad y aplicabilidad de los Lenguajes de Patrones, se convierte en una herramienta importante para diseñadores e implementadores  de todo tipo de sistemas de informació