243 research outputs found
Existence and Uniqueness of Abstract Stochastic Fractional-Order Differential Equation
In this paper, the existence and uniqueness about the solution for a class of abstract stochastic fractional-order differential equations
where in and are given functions, are investigated, where the fractional derivative is described in Caputo sense. The fractional calculus, stochastic analysis techniques and the standard iteration method are used to obtain the required
A Unique Solution of Stochastic Partial Differential Equations with Non-Local Initial condition
In this paper, we shall discuss the uniqueness ”pathwise uniqueness” of the solutions of stochastic partial differential equations (SPDEs) with non-local initial condition,We shall use the Yamada-Watanabe condition for ”pathwise uniqueness” of the solutions of the stochastic differential equation; this condition is weaker than the usual Lipschitz condition. The proof is based on Bihari’sinequality
Purification and characterization of alginate lyase from locally isolated marine Pseudomonas stutzeri MSEA04
An alginate lyase with high specific enzyme activity was purified from Pseudomonas stutzeri MSEA04, isolated from marine brown algae. The alginate lyase was purified by precipitation with ammonium sulphate, acetone and ethanol individually. 70% ethanol fraction showed maximum specific activity (133.3 U/mg). This fraction was re-purified by anion exchange chromatography DEAE- Cellulose A-52. The loaded protein was separated into 3 peaks. The second protein peak was the major one which contained 48.2% of the total protein recovered and 79.4% of the total recovered activity. The collected fractions of this peak were subjected to further purification by re-chromatography on Sephadex G-100. Alginate lyase activity was fractionated in the Sephadex column into one major peak, and the specific activity of this fraction reached 116 U/mg. The optimal substrate concentration, pH and temperature for alginate lyase activity were 8 mg/ml, pH 7.5 and 37 °C, respectively. While, Km and Vmax values were 1.07 mg alginate/ ml and 128.2 U/mg protein, respectively. The enzyme was partially stable below 50 °C, and the activity of the enzyme was strongly enhanced by K+, and strongly inhibited by Ba+2, Cd+2, Fe+2 and Zn+2. The purified enzyme yielded a single band on SDS-PAGE with molecular weight (40.0 kDa)
Synthesis of New Formyl Halo N-methylimidazole Derivatives
Bromo-formyl imidazoles 16-20 have been prepared by three
different ways. The first consisted of conversion of bromo or iodo
imidazoles 1-6 into diethyl acetals 13-15, and subsequent hydrolysis
into formyl derivatives 7-9. In the second, bromination of.
formyl imidazoles with NBS afforded compounds 16-18 in 45-70°/o
yield. The third method used direct formylation of bromo imidazoles
10-12 with n-BuLi/DMF reagent into compounds 16, 19, and 20
Synthesis, dyeing performance on polyester fiber and antimicrobial studies of some novel pyrazolotriazine and pyrazolyl pyrazolone azo dyes
Abstract5-Amino-4-heterylazo-3-phenyl-1H-pyrazoles (2a–d) were diazotized and coupled with malononitrile to give pyrazoloazo malononitrile which by heating in glacial acetic acid gave novel pyrazolo[5,1-c][1,2,4]triazine dyes (3a–d). Also, some diazopyrazolyl pyrazolone dyes (4a–h) were synthesized by diazotization of 2a–d and coupled with some pyrazolone derivatives. The structure of the synthesized dyes was determined by elemental analysis and spectral data. All the synthesized compounds were applied as disperse dyes and their dyeing performance on polyester fabric was studied. The fastness and colorimetric properties were measured. The results revealed that the monoazo dyes have good fastness and good to moderate affinity to polyester fabric than diazo dyes. In addition, the synthesized dyes were screened for their antimicrobial activities against Staphylococcus aureus, Pseudomonas aeruginosa (Gram positive), Bacillus subtitles, Escherichia coli (Gram negative) and Candida albicans, Aspergillus niger (Fungi). The results revealed that most of the prepared dyes have high antibacterial activity
Purification and characterization of alginate lyase from locally isolated marine Pseudomonas stutzeri
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Study of biochemical changes after plateletpheresis in healthy male donors
BACKGROUND: There is relatively little information about endogenous biochemical changes in a response to plateletpheresis in healthy donors. We aimed to investigate the changes in different biochemical parameters including glycemic status, insulin resistance, iron status, lipid profile and inflammatory markers after plateletpheresis in healthy male donors with normal glycemic status. METHODS: In this study we enrolled 10 male subjects. The glycemic status in all subjects was assessed using an oral glucose tolerance test pre- and post-plateletpheresis at different time intervals (1, 8 and 22 days). Different biochemical parameters including glucose, HbA1c, insulin, lipids, uric acid, transferrin, ferritin, C-reactive protein and insulin resistance were measured. Repeated ANOVA was utilized for the purpose of statistical comparison of means between different days. RESULTS: Fasting glucose, transferrin, cholesterol, triglycerides, HDL-C, and LDL-C were significantly altered (-3.9%, p<0.05; -2.7%, p<0.05; -3.9%, p<0.05; 23.9%, p<0.05; -5.5%, p<0.01; and -9.2%, p<0.05 respectively) at day 1 following plateletpheresis. There was a gradual reduction in HbA1c and ferritin levels during the time-course of the study, and by day 22, both were significantly lower (-2.0%, p<0.01; -18.1%, p<0.05 respectively) when compared to the pre-plateletpheresis levels. CONCLUSIONS: Post-plateletpheresis, several biochemical parameters may change significantly in healthy donors. The changes were particularly evident one and 22 days after donation. The potential effects of plateletpheresis need to be considered when interpreting biochemical tests
Selection of the appropriate method for the assessment of insulin resistance
Insulin resistance is one of the major aggravating factors for metabolic syndrome. There are many methods available for estimation of insulin resistance which range from complex techniques down to simple indices. For all methods of assessing insulin resistance it is essential that their validity and reliability is established before using them as investigations. The reference techniques of hyperinsulinaemic euglycaemic clamp and its alternative the frequently sampled intravenous glucose tolerance test are the most reliable methods available for estimating insulin resistance. However, many simple methods, from which indices can be derived, have been assessed and validated e.g. homeostasis model assessment (HOMA), quantitative insulin sensitivity check index (QUICKI). Given the increasing number of simple indices of IR it may be difficult for clinicians and researchers to select the most appropriate index for their studies. This review therefore provides guidelines and advices which must be considered before proceeding with a study
AN ANALYSIS OF TWO DIMENSIONAL INTEGRAL EQUATIONS OF THE SECOND KIND
In this article, a numerical method is used to solve the two dimensionalFredholm integral equation of the second kind with weak singular kernel using the Toeplitz matrix and product Nystrom method. The numerical results given in this paper are computed using maple 8. The error, in each case, is computed.In this article, A numerical method is used to solve the two dimensionalFredholm integral equation of the second kind with weak singular kernel using the Toeplitz matrix and product Nystrom method. The numerical results given in this paper are computed using maple 8. The error, in each case, is computed
The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults-A cross sectional study
Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation in non-diabetic Saudi adults hoping to improve current Saudi guidelines to prevent cardiovascular disease. Volunteers were recruited randomly from public healthcare centers in Jeddah. Demographic information, blood pressure (BP), and anthropometric measurements were taken. Fasting blood samples were drawn, then again following 1-hour oral glucose tolerance test. Glycated hemoglobin, fasting plasma glucose (FPG), lipid profile, highly sensitive C- reactive protein, gamma glutamyl transferase, and 1-hour plasma glucose were measured. Complete data was found for 742 men and 592 women. Pre-hypertension was found in 47.2% of men, and 24.7% of women, while 15.1% of men, and 14.6% of women were hypertensive. Means of measured variables differed significantly between normotensive, pre-hypertensive, and hypertensive groups of men and women in gender specific manner. Association between measured variables and elevated BP, and hypertension were assessed using logistic regression models. After adjustment for age, body mass index and waist circumference, elevated blood pressure was associated with elevated triglycerides in men, while hypertension was significantly associated with elevated fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein- cholesterol, and low high density lipoprotein- cholesterol in men, and elevated triglycerides, and total cholesterol in women. Therefore, it is strongly recommended to measure lipid profile, specifically TG, for all diagnosed pre-hypertensive and hypertensive patients in addition to FPG for men.Peer reviewe
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