33 research outputs found
Characterization and Analysis of β-Glucosidase B (BglB) Mutant M114S
The goal of the Design to Data project is to improve the ability of modeling software to predict protein function from structure. We generated a single point mutation in BgIB, M114S, and performed kinetic and thermal assays to gather empirical data. Based on previously published data on similar mutations, such as M261D, and an overall change in Foldit score greater than 1, we hypothesize that M114S will demonstrate decreased catalytic efficiency and thermal stability in comparison to the wild-type. We were unable to confirm or deny or negate our hypothesis as our data indicated that M114S was not expressed
Steam sauna and mother roasting in Lao PDR: practices and chemical constituents of essential oils of plant species used in postpartum recovery
<p>Abstract</p> <p>Background</p> <p>Fundamental in traditional postpartum recovery in Lao PDR is the use of hotbeds, mother roasting, steam sauna and steam baths. During these treatments medicinal plants play a crucial role, but little has been published about how the treatments are carried out precisely, which species are used, the medicinal properties of these species, and the medicinal efficacy of their chemical constituents.</p> <p>Methods</p> <p>Sixty-five interviews, in 15 rural villages, with women of 4 different ethnic groups were conducted to survey confinement rituals, and postpartum plant use and salience. Essential oils from the main species used were extracted using steam distillation and the main chemical constituents characterized using gas chromatography-mass spectrometry (GC-MS).</p> <p>Results</p> <p>A total of 10 different species were used by three or more of the ethnic groups included in this study. All species were used in steam sauna and bath, but only 3 species were used in hotbed and mother roasting. Essential oils of <it>Amomum villosum, Amomum microcarpum </it>and <it>Blumea balsamifera </it>were found to contain significant amounts of the following terpenes: β-pinene, camphor, bornyl acetate, borneol, linalool, D-limonene, fenchone, terpinen-4-ol and α-terpinene.</p> <p>Conclusions</p> <p>Many of these terpenes have documented antimicrobial and analgesic properties, and some have also synergistic interactions with other terpenes. The mode of application in hotbed and mother roasting differs from the documented mechanisms of action of these terpenes. Plants in these two practices are likely to serve mainly hygienic purposes, by segregating the mother from infection sources such as beds, mats, stools, cloth and towels. Steam sauna medicinal plant use through inhalation of essential oils vapors can possibly have medicinal efficacy, but is unlikely to alleviate the ailments commonly encountered during postpartum convalescence. Steam sauna medicinal plant use through dermal condensation of essential oils, and steam bath cleansing of the perineal area is possibly a pragmatic use of the reported medicinal plants, as terpene constituents have documented antimicrobial, analgesic and anti-inflammatory properties.</p
Les Kiao-Tche, Ă©tude Ă©tymologique et anthropologique
Bonifacy . Les Kiao-Tche, étude étymologique et anthropologique. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, V° Série. Tome 9, 1908. pp. 699-706
Le laquage des Dents en noir chez les Annamites
Bonifacy . Le laquage des Dents en noir chez les Annamites. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, V° Série. Tome 8, 1907. pp. 437-440
Nouvelles recherches sur les génies theriomorphes au Tonkin
Bonifacy Auguste L. M. Nouvelles recherches sur les génies theriomorphes au Tonkin. In: Bulletin de l'Ecole française d'Extrême-Orient. Tome 14, 1914. pp. 19-27
M. Abadie : Les races du Haut Tonkin de Phong-tho Ă Lang-son
Bonifacy Auguste L. M. M. Abadie : Les races du Haut Tonkin de Phong-tho à Lang-son. In: Bulletin de l'Ecole française d'Extrême-Orient. Tome 24, 1924. pp. 588-594
Recherches sur les génies thériomorphes au Tonkin — (3e série)
Bonifacy Auguste L. M. Recherches sur les génies thériomorphes au Tonkin — (3e série). In: Bulletin de l'Ecole française d'Extrême-Orient. Tome 18, 1918. pp. 1-50
Communication au sujet de l'antiquité du fer en Chine, chez les Chinois et chez les Préchinois
Bonifacy . Communication au sujet de l'antiquité du fer en Chine, chez les Chinois et chez les Préchinois. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, V° Série. Tome 8, 1907. pp. 512-514
Les MĂ©tis franco-tonkinois
Bonifacy . Les Métis franco-tonkinois. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, VI° Série. Tome 1, 1910. pp. 607-642