Synthesis, characterization, antibacterial activity and 3D-molecular modeling of some oxoperoxomolybdenum(VI) chelates in mixed (O,O) coordination environment involving 2-hydroxy-1-naphthaldehyde and β-diketoenolates

1333-1342A new series of four mixed-ligand complexes of oxoperoxomolybdenum(VI) of the general composition, [MoO(O₂)(2-hnd)(L)]H₂O, where 2-hndH = 2-hydroxy-1-naphthaldehyde and LH = o-acetoacetanisidide (o-aansH), o-acetoacetotoluidide (o-aatdH), acetylacetone (acacH) or methyl acetoacetate (macacH), has been synthesized by the interaction of [MoO(O₂)]²⁺ (in situ obtained during the interaction of MoO₃ and 30% H₂O₂ on continuous stirring at 50C for 24 h) and the ligands in aquous-ethanol medium. The complexes so obtained have been characterized by elemental analyses, molar conductance, decomposition temperature and magnetic measurements, thermogravimetric studies, ¹H-NMR, IR, mass and electronic spectral studies. Antibacterial studies of the ligand and the metal complexes have also been carried out. The complexes have been found to be more potent bactericides than the ligands. The 3D-molecular modeling and analysis for both bond lengths and bond angles have also been carried out for one of the representative compounds, [MoO(O₂)(2-hnd)(o-aatd)]H₂O (1), to substantiate the proposed structure. Pseudopentagonal bipyramidal structures have been proposed for these complexes

Oxoperoxomolybdenum(VI) complexes of catalytic and biomedical relevance: Synthesis, characterization, antibacterial activity and 3D-molecular modeling of some oxoperoxomolybdenum(VI) chelates in mixed (O,O) coordination environment involving maltol and β-diketoenolates

A new series of four mixed-ligand complexes of oxoperoxomolybdenum(VI) of the general composition [MoO(O2)(ma)(L)]·H2O, where maH = 3-hydroxy-2-methyl-4-pyrone and LH = o-acetoacetanisidide (o-aansH), o-acetoacetotoluidide (o-aatdH), acetylacetone (acacH) or methylactoacetate (macacH), has been synthesized by the interaction of [MoO(O2)]2+ (obtained in situ during the interaction of MoO3 and 30% H2O2 on continuous stirring at 50 °C for 24 h) and the said ligands in aqueous-ethanol medium. The complexes so obtained have been characterized by elemental analyses, molybdenum determination, molar conductance, decomposition temperature and magnetic measurements, thermogravimetric studies, 1H NMR, IR, mass and electronic spectral studies. Antibacterial studies of one of the ligands maltol and the two representative metal complexes were also carried out and it has been observed that the complexes are more potent bactericides than the ligand. The 3D-molecular modeling and analysis for bond lengths and bond angles have also been carried out for one of the representative compound (1) to substantiate the proposed structure. Pseudopentagonal bipyramidal structures have been proposed for these complexes

Manganese(II) chelates of bioinorganic and medicinal relevance: Synthesis, characterization, antibacterial activity and 3D-molecular modeling of some penta-coordinated manganese(II) chelates in O,N-donor coordination matrix of β-diketoenolates and picolinate

Four new mixed-ligand complexes of manganese(II) of the composition [Mn(pa)(L)(H2O)], where paH = picolinic acid and LH = acetoacetanilide (aaH), o-acetoacetanisidide (o-aansH), o-acetoacetotoluidide (o-aatdH) or ethylacetoacetate (eacacH), have been synthesized by the interaction of MnCl2·4H2O with the said ligands in aqueous-ethanol medium. The complexes so obtained have been characterized on the basis of elemental analyses, molar conductance and magnetic measurements, thermogravimetric analyses, mass, EPR, infrared and electronic spectral studies. Synthesized complexes have shown significantly greater antibacterial activity against Escherichia coli and Vibrio cholera than ligands. The 3D-molecular modeling and analysis for bond lengths and bond angles have also been carried out for one of the representative compound [Mn(pa)(aa)(H2O)] (1) to substantiate the proposed structures