7 research outputs found
Photoperiod, Ambient Temperature, and Food Availability Interact to Affect Reproductive and Immune Function in Adult Male Deer Mice ( Peromyscus maniculatus
Different photoperiods affect proliferation of lymphocytes but not expression of cellular, humoral, or innate immunity in hamsters
In seasonal mammals, photoperiod change is associated with a suite of alterations in physiology. It has recently been proposed that the immune response is one of the systems regulated by changes in photoperiod, although this hypothesis has not been rigorously challenged by assays of functional immune responses. The aim of this study was to test the hypothesis that photoperiod modulates immune responsiveness in Syrian (Mesocricetus auratus) and Siberian (Phodopus sungorus) hamsters. Consistent with previously reported data, short-day-housed (SD) animals exhibited a significant increase in lymphnode cell (LNC) numbers and increased cellular proliferation in response to the polyclonal mitogen concanavalin A compared to long-day-housed (LD) animals. In contrast, LNC numbers from intact or gonadectomized SD animals that had been sensitized with the antigen dinitrofluorobenzene (DNFB) exhibited a reduced ex vivo proliferative response and reduced production of interleukin-6(IL-6) compared to LD animals. In vivo studies of the contact hypersensitivity response of animals that had previously been sensitized, and subsequently challenged, with DNFB were similar in SD and LD animals, as was the proliferative activity of LNC recovered from these animals. There were also no photoperiodic differences in the antidinitrophenyl antibody response of animals sensitized with DNFB, or the anti-sheep red blood cell (srbc) response of animals immunized with srbc. Furthermore, no differences could be detected in the activity of natural killer cells from spleens of LD and SD Siberian hamsters, or in lipopolysaccharide-induced IL-6 production by LD and SD Syrian hamsters invivo. Thus, although photoperiod is able to influence factors regulating the gross number and non-antigen-specific proliferation of lymphocytes in seasonally breeding mammals, day length does not directly influence activation of an effective immune response. The authors conclude, therefore, that expression of the immune response is not directly modified or compromised by photoperiod in these seasonally breeding hamster species
Trauma-informed care in childcare organisations to support children exposed to child maltreatment: Joint conclusions of four European countries
Trauma-informed care is emerging as a promising good practice to recognise, treat and prevent trauma in young children. The use of trauma-informed care in childcare organisations might have a positive impact on children who suffer from child maltreatment. The current study organised desk research and focus group discussions with professional experts in Latvia, Italy, Hungary and Belgium to assess if trauma-informed care is known, applied or taught. The joint conclusions of the desk research and the focus group discussions demonstrated that childcare professionals currently lack the knowledge, skills and attitude to engage in trauma-informed care. Even though they have ways to prevent and tackle trauma, these ways are often based on gut feeling or experience and are not formalised or explicitly addressed. This lack of conscious knowhow is an issue that possibly leads to underreporting of situations of child maltreatment and a lack of attuned responses to children suffering from child maltreatment. Overall, there were no training initiatives focused on trauma-informed care for childcare professionals, which might explain why these good practices do not reach the sector
Recommendations for the surveillance of mental health problems in childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group
Is the herb-shrub composition of veredas (Brazilian palm swamps) distinguishable?
<div><p>ABSTRACT Vereda (Brazilian palm swamp) is a poorly known savannic phytophysiognomy that occurs on moist soils with high herb-shrub floristic richness. This study aimed to document the herb-shrub species of veredas of the Estação Ecológica Serra Geral do Tocantins - EESGTO, and compare this flora with other veredas in Brazil. Furthermore, we assessed the similarity of the herb-shrub flora of the studied veredas with that of inventories of other savannas and grasslands in order to evaluate whether veredas possess an exclusive flora. Ordination analysis was performed to understand the floristic relationship among these areas. We recorded 213 species, 105 genera and 49 families at EESGTO, including five new floral records for the Cerrado and 78 for the state of Tocantins. The floristic similarity among veredas at EESGTO and the other sites was low. For all sites, a total of 1,324 species were recorded, of which 342 were unique to veredas and 187 unique to moist grasslands (campos limpos úmidos). After reviewing databases, 14.3 % of these species remained exclusive to veredas and moist grasslands. The ordination analysis indicated a gradient in floristic composition from wet to dry phytophysiognomies. In conclusion, we recognize a flora that distinguishes veredas from other Cerrado phytophysiognomies.</p></div