A MEMS Photoacoustic Detector of Terahertz Radiation for Chemical Sensing

A piezoelectric Microelectromechanical system (MEMS) cantilever pressure sensor was designed, modeled, fabricated, and tested for sensing the photoacoustic response of gases to terahertz (THz) radiation. The sensing layers were comprised of three thin films; a lead zirconate titanate (PZT) piezoelectric layer sandwiched between two metal contact layers. The sensor materials were deposited on the silicon device layer of a silicon-on-insulator (SOI) wafer, which formed the physical structure of the cantilever. To release the cantilever, a hole was etched through the backside of the wafer and the buried oxide was removed with hydrofluoric acid. Devices were then tested in a custom made THz vacuum test chamber. Cantilever deflection was observed with a laser interferometer in the test chamber and preliminary data indicates the signals were caused by the photoacoustic effect. Future device data will also include the piezoelectric voltage signal analysis

Norovirus genotypes in endemic acute gastroenteritis of infants and children in Finland between 1994 and 2007

Noroviruses are, after rotaviruses, the second most common causative agents of acute gastroenteritis in young children. We studied norovirus genotypes in faecal specimens collected from Finnish children followed-up prospectively in rotavirus vaccine trials. Almost 5000 faecal specimens collected from cases of acute gastroenteritis were examined using reverse transcriptase–PCR. A total of 1172 cases (25% of all acute gastroenteritis) were associated with noroviruses. Of these, 96% were genogroup GII. GII.4 was the most common genotype (46%) throughout the study period but the proportion of this genotype varied in different norovirus epidemic seasons. Additional norovirus genotypes detected were: GII.7 (15%), GII.3 (14%), GII.1 (9%), GII.b (7%), GII.2 (3%), and GI.3 (2%). GII.4 dominated during the following years: 1998–1999 (75%), 2002–2003 (88%) and 2006–2007 (98%) while recombinant genotype GII.b was dominant between 2003 and 2004 (83%). In conclusion, genotypes GII.4 and GIIb have emerged as predominant norovirus genotypes in endemic gastroenteritis affecting young infants and children in Finland

Study of refractive structure in the inelastic 16O+16O scattering at the incident energies of 250 to 1120 MeV

The data of inelastic 16O+16O scattering to the lowest 2+ and 3- excited states of 16O have been measured at Elab = 250, 350, 480, 704 and 1120 MeV and analyzed consistently in the distorted wave Born approximation (DWBA), using the semi- microscopic optical potentials and inelastic form factors given by the folding model, to reveal possible refractive structure of the nuclear rainbow that was identified earlier in the elastic 16O+16O scattering channel at the same energies. Given the known transition strengths of the 2+ and 3- states of 16O well determined from the (e,e') data, the DWBA description of the inelastic data over the whole angular range was possible only if the absorption in the exit channels is significantly increased (especially, for the 16O+16O(2+) exit channel). Although the refractive pattern of the inelastic 16O+16O scattering was found to be less pronounced compared to that observed in the elastic scattering channel, a clear remnant of the main rainbow maximum could still be seen in the inelastic cross section at Elab = 350 - 704 MeV.Comment: 26 pages, 10 figures, Accepted for publication in Nucl. Phys.

A comparison of methods for purification and concentration of norovirus GII-4 capsid virus-like particles

Noroviruses (NoVs) are one of the leading causes of acute gastroenteritis worldwide. NoV GII-4 VP1 protein was expressed in a recombinant baculovirus system using Sf9 insect cells. Several methods for purification and concentration of virus-like particles (VLPs) were evaluated. Electron microscopy (EM) and histo-blood group antigen (HBGA) binding assays showed that repeated sucrose gradient purification followed by ultrafiltration resulted in intact VLPs with excellent binding to H type 3 antigens. VLPs were stable for at least 12 months at 4°C, and up to 7 days at ambient temperature. These findings indicate that this method yielded stable and high-quality VLPs

Detailed studies of the transverse beam characteristics of laser produced ion beams

We present the first systematic measurement of the transverse parameters of laser produced proton beam. We find a similarity for the shape of the accelerating sheath, which is always close to a parabola. We find also a similarity for the relation between source size and proton energy with the maximum source size and proton energy as a free parameter, which is confirming the similarity we already found for the sheath shape. This is of particular interest for the application of laser produced proton beams as it shows the scalability of the transverse beam parameter

Seeing eye to eye: social augmented reality and shared decision making in the marketplace

Firms increasingly seek to improve the online shopping experience by enabling customers to exchange product recommendations through social augmented reality (AR). We utilize socially situated cognition theory and conduct a series of five studies to explore how social AR supports shared decision making in recommender–decision maker dyads. We demonstrate that optimal configurations of social AR, that is, a static (vs. dynamic) point-of-view sharing format matched with an image-enhanced (vs. text-only) communicative act, increase recommenders’ comfort with providing advice and decision makers’ likelihood of using the advice in their choice. For both, these effects are due to a sense of social empowerment, which also stimulates recommenders’ desire for a product and positive behavioral intentions. However, recommenders’ communication motives impose boundary conditions. When recommenders have strong impression management concerns, this weakens the effect of social empowerment on recommendation comfort. Furthermore, the stronger a recommender’s persuasion goal, the less likely the decision maker is to use the recommendation in their choice