Pasts and pagan practices: moving beyond Stonehenge

Theorizing the past is not restricted to archaeology and interpretations of 'past' both influence and are themselves constituted within politicized understandings of self, community and in certain instances, spirituality. 'The past in the imagination of the present' is appropriated, variously, to give meaning to the present or to justify actions and interpret experiences. Summer solstice at Stonehenge, with an estimated 21,000 celebrants in 2005, is only the most publicized appropriation (by pagans and other adherents of alternative spirituality and partying) of a 'sacred site'; and conflicts and negotiations occurring throughout Britain are represented in popular and academic presentations of this 'icon of Britishness'. This paper presents work from the Sacred Sites, Contested Rites/Rights Project (http://www.sacredsites.org.uk) project, a collaboration of archaeology and anthropology informed by pagan and alternative approaches and standpoints investigating and theorizing discourse and practice of heritage management and pagan site users. Whether in negotiations around the Stonehenge solstice access or in dealing with numerous other sites, boundaries between groups or discourses are not clearly drawn - discursive communities merge and re-emerge. But clearly 'past' and 'site' are increasingly important within today's Britain, even as television archaeology increases its following, and pagan numbers continue to grow.</p

Mitochondrial Dysfunction in Parkinson's Disease

Parkinson's disease (PD) is a progressive, neurodegenerative condition that has increasingly been linked with mitochondrial dysfunction and inhibition of the electron transport chain. This inhibition leads to the generation of reactive oxygen species and depletion of cellular energy levels, which can consequently cause cellular damage and death mediated by oxidative stress and excitotoxicity. A number of genes that have been shown to have links with inherited forms of PD encode mitochondrial proteins or proteins implicated in mitochondrial dysfunction, supporting the central involvement of mitochondria in PD. This involvement is corroborated by reports that environmental toxins that inhibit the mitochondrial respiratory chain have been shown to be associated with PD. This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area

Lensing-Induced Structure of Submillimeter Sources: Implications for the Microwave Background

We consider the effect of lensing by galaxy clusters on the angular distribution of submillimeter wavelength objects. While lensing does not change the total flux and number counts of submillimeter sources, it can affect the number counts and fluxes of flux-limited samples. Therefore imposing a flux cut on point sources not only reduces the overall Poisson noise, but imprints the correlations between lensing clusters on the unresolved flux distribution. Using a simple model, we quantify the lensing anisotropy induced in flux-limited samples and compare this to Poisson noise. We find that while the level of induced anisotropies on the scale of the cluster angular correlation length is comparable to Poisson noise for a slowly evolving cluster model, it is negligible for more realistic models of cluster evolution. Thus the removal of point sources is not expected to induce measurable structure in the microwave or far-infrared backgrounds.Comment: 22 pages, 9 figures, accepted to Astrophysical Journa

Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids

Ionic liquids are salts used in a variety of industrial processes, and being relatively non-volatile, are proposed as environmentally-friendly replacements for existing volatile liquids. Methylimidazolium ionic liquids resist complete degradation in the environment, likely because the imidazolium moiety does not exist naturally in biological systems. However, there is limited data available regarding their mammalian effects in vivo. This study aimed to examine the effects of exposing mice separately to 2 different methylimidazolium ionic liquids (BMI and M8OI) through their addition to drinking water. Potential effects on key target organs-the liver and kidney-were examined, as well as the gut microbiome. Adult male mice were exposed to drinking water containing ionic liquids at a concentration of 440 mg/L for 18 weeks prior to examination of tissues, serum, urine and the gut microbiome. Histopathology was performed on tissues and clinical chemistry on serum for biomarkers of hepatic and renal injury. Bacterial DNA was isolated from the gut contents and subjected to targeted 16S rRNA sequencing. Mild hepatic and renal effects were limited to glycogen depletion and mild degenerative changes respectively. No hepatic or renal adverse effects were observed. In contrast, ionic liquid exposure altered gut microbial composition but not overall alpha diversity. Proportional abundance of Lachnospiraceae, Clostridia and Coriobacteriaceae spp. were significantly greater in ionic liquid-exposed mice, as were predicted KEGG functional pathways associated with xenobiotic and amino acid metabolism. Exposure to ionic liquids via drinking water therefore resulted in marked changes in the gut microbiome in mice prior to any overt pathological effects in target organs. Ionic liquids may be an emerging risk to health through their potential effects on the gut microbiome, which is implicated in the causes and/or severity of an array of chronic disease in humans

Diversity Graphs

Bipartite graphs have long been used to study and model matching problems, and in this paper we introduce the bipartite graphs that explain a recent matching problem in computational biology. The problem is to match haplotypes to genotypes in a way that minimizes the number of haplotypes, a problem called the Pure Parsimony problem. The goal of this work is not to address the computational or biological issues but rather to explore the mathematical structure through a study of the underlying graph theory

The Chandra Deep Field-North Survey. XIV. X-ray detected Obscured AGNs and Starburst Galaxies in the Bright Submm Source Population

We provide X-ray constraints and perform the first X-ray spectral analyses for bright (f_850>=5mJy; S/N>=4) SCUBA sources in an 8.4'x8.4' area of the 2 Ms Chandra Deep Field-North survey containing the Hubble Deep Field-North. X-ray emission is detected from 7 of the 10 bright submm sources in this region, corresponding to an X-ray detected submm source density of ~360 deg^-2 (>~36% of the bright submm source population). Two of the X-ray detected sources have nearby (within 3") X-ray companions, suggesting merging/interacting sources or gravitational lensing effects, and 3 lie within the approximate extent of a proto-cluster candidate. Five of the X-ray detected sources have flat X-ray spectral slopes, suggesting obscured AGN activity. X-ray spectral analyses suggest that one of these AGNs may be a Compton-thick source; of the other 4 AGNs, 3 appear to be Compton-thin sources and one has poor constraints. The rest-frame unabsorbed X-ray luminosities of these AGNs are more consistent with those of Seyfert galaxies than QSOs. Thus, the low X-ray detection rate of bright submm sources by moderately deep X-ray surveys appears to be due to the relatively low luminosities of the AGNs rather than Compton-thick absorption. A comparison of these sources to the well-studied heavily obscured AGN NGC6240 shows that the average AGN contribution is negligible at submm wavelengths. The X-ray properties of the other 2 X-ray detected sources are consistent with those expected from luminous star formation; however, we cannot rule out the possibility that low-luminosity AGNs are present. The 3 X-ray undetected sources appear to lie at high redshift (z>4) and could be either AGNs or starbust galaxies.Comment: AJ in press (February 2003), 16 pages, includes emulateapj5.st

SCUBA sub-millimeter observations of gamma-ray bursters IV. GRB 021004, 021211, 030115, 030226, 041006

We discuss our ongoing program of Target of Opportunity (ToO) sub-millimeter observations of gamma-ray bursts (GRBs) using the Sub-millimetre Common-User Bolometer Array (SCUBA) on the James Clerk Maxwell Telescope (JCMT). In this paper, we present the ToO observations of GRBs 021004, 021211, 030115, 030226, and 041006. The observations of GRBs 021004, 021211, 030226, and 041006 all started within ~1 day of the burst, but did not detect any significant sub-millimeter emission from the reverse shock and/or afterglow. These observations put some constraints on the models for the early emission, although the generally poor observing conditions and/or the faintness of these afterglows at other wavelengths limit the inferences that can be drawn from these lack of detections. However, these observations demonstrate that SCUBA can perform rapid observations of GRBs, and provide encouragement for future observations in the Swift era. None of these GRBs had significant sub-millimeter emission from their host galaxies. This adds to the indication that GRBs are not closely linked to the most luminous dusty star-forming galaxies.Comment: 10 pages, 1 color figure (no information lost if printed in black and white

Dallas with balls: televized sport, soap opera and male and female pleasures

Two of the most popular of television genres, soap opera and sports coverage have been very much differentiated along gender lines in terms of their audiences. Soap opera has been regarded very much as a 'gynocentric' genre with a large female viewing audience while the audiences for television sport have been predominantly male. Gender differentiation between the genres has had implications for the popular image of each. Soap opera has been perceived as inferior; as mere fantasy and escapism for women while television sports has been perceived as a legitimate, even edifying experience for men. In this article the authors challenge the view that soap opera and television sport are radically different and argue that they are, in fact, very similar in a number of significant ways. They suggest that both genres invoke similar structures of feeling and sensibility in their respective audiences and that television sport is a 'male soap opera'. They consider the ways in which the viewing context of each genre is related to domestic life and leisure, the ways in which the textual structure and conventions of each genre invoke emotional identification, and finally, the ways in which both genres re-affirm gender identities