353 research outputs found

    Simultaneous measurement of gastric emptying of a soup test meal using MRI and gamma scintigraphy

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    Measurement of gastric emptying is of clinical value for a range of conditions. Gamma scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) has recently increased. Previous comparison studies between MRI and GS showed good correlation, but were performed on separate study days. In this study, the modalities were alternated rapidly allowing direct comparison with no intra-individual variability confounds. Twelve healthy participants consumed 400 g of Technetium-99m (99mTc)-labelled soup test meal (204 kcal) and were imaged at intervals for 150 min, alternating between MRI and GS. The time to empty half of the stomach contents (T1/2) and retention rate (RR) were calculated and data correlated. The average T1/2 was similar for MRI (44 ± 6 min) and GS (35 ± 4 min) with a moderate but significant difference between the two modalities (p ≀0.004). The individual T1/2 values were measured, and MRI and GS showed a good positive correlation (r = 0.95, p ≀ 0.0001), as well as all the RRs at each time point up to 120 min. Gastric emptying was measured for the first time by MRI and GS on the same day. This may help with translating the use of this simple meal, known to elicit reliable, physiological, and pathological gastrointestinal motor, peptide, and appetite response

    Respectable Drinkers, Sensible Drinking, Serious Leisure: Single-Malt Whisky Enthusiasts and the Moral Panic of Irresponsible Others

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    In the public discourse of policy-makers and journalists, drinkers of (excessive) alcohol are portrayed either as irresponsible, immoral deviants or as gullible victims. In other words, the public discourse engenders a moral panic about alcohol-crazed individuals, who become what Cohen [1972. Folk devil and moral panics. London: Routledge] identifies as folk devils: the Other, abusing alcohol to create anti-social disorder. However, alcohol-drinking was, is and continues to be an everyday practice in the leisure lives of the majority of people in the UK. In this research article, I want to explore the serious leisure of whisky-tasting to provide a counter to the myth of the alcohol-drinker as folk devil, to try to construct a new public discourse of sensible drinking. I will draw on ethnographic work at whisky-tastings alongside interviews and analysis of on-line discourses. I show that participation in whisky-tasting events creates a safe space in which excessive amounts of alcohol are consumed, yet the norms of the particular habitus ensure that such drinking never leads to misbehaviour. In doing so, however, I will note that the respectability of whisky-drinking is associated with its masculine, white, privileged habitus – the folk devil becomes someone else, someone Other

    'It's just superstition I suppose ... I've always done something on game day': The construction of everyday life on a university basketball team

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    Research in sport has tended to focus on ‘spectacular’ or ‘extra-ordinary’ experiences, at the expense of discussing how particular phenomena are embedded in everyday life. Drawing on ethnographic research with a university basketball team in the North of England, this article considers the meanings that amateur players attach to basketball and how such meanings go beyond their participation in competitive games. Analysis reveals the rhythms and rituals which are hugely important in determining the players’ sense of self. It also highlights the carnivalesque celebrations which allow the players to temporarily disrupt the status quo and experiment with alternative identities. In conclusion, it is argued that the meaning of sport should not be seen as rigid, determining and predictable, but rather a creative experience that is largely dependent on the subjective appropriation of time and place

    Veterinary students' views on animal patiens and human clients, using Q methodology

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    Veterinarians serve two masters: animal patients and human clients. Both animal patients and human clients have legitimate interests, and conflicting moral claims may flow from these interests. Earlier research concludes that veterinary students are very much aware of the complex and often paradoxical relationship they have and will have with animals. In this article the views of veterinary students about their anticipated relationship with animal patients and human clients are studied. The main part of the article describes discourses of first-year and fourth-year students about their (future) relationship with animals and their caretakers, for which Q-methodology is used. At the end of the article, the discourses are related to the students' gender and their workplace preferences. © 2007 AAVMC

    Management and Tillage Infl uence Barley Forage Productivity and Water Use in Dryland Cropping Systems

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    Annual cereal forages are resilient in water use (WU), water use efficiency (WUE), and weed control compared with grain crops in dryland systems. The combined influence of tillage and management systems on annual cereal forage productivity and WU is not well documented. We conducted a field study for the effects of tillage (no-till and tilled) and management (ecological and conventional) systems on WU and performance of forage barley (Hordeum vulgare L.) and weed biomass in two crop rotations (wheat [Triticum aestivum L.]–forage barley–pea [Pisum sativum L.] and wheat–forage barley–corn [Zea mays L.] –pea) from 2004 to 2010 in eastern Montana. Conventional management included recommended seeding rates, broadcast N fertilization, and short stubble height of wheat. Ecological management included 33% greater seeding rates, banded N fertilization at planting, and taller wheat stubble. Forage barley in ecological management had 28 more plants m–2, 2 cm greater height, 65 more tillers m–2, 606 kg ha–1 greater crop biomass, 3.5 kg ha–1 mm–1greater WUE, and 47% reduction in weed biomass at harvest than in conventional management. Pre-plant and post-harvest soil water contents were similar among tillage and management systems, but barley WU was 13 mm greater in 4-yr than 3-yr rotation. Tillage had little effect on barley performance and WU. Dryland forage barley with higher seeding rate and banded N fertilization in more diversified rotation produced more yield and used water more efficiently than that with conventional seeding rate, broadcast N fertilization, and less diversified rotation in the semiarid northern Great Plains

    We can have the cake and eat it too: leisure and spirituality at ‘veiled’ hotels in Turkey

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    This paper uses ethnographic methods to inquire how new forms of consumption arise as a result of bridging Islamic spirituality with leisure in the newly growing tesettĂŒr hotels in Turkey, which have become a magnet of popular and academic attention. We aim to offer a multi-layered analysis of the leisure and consumption practices of Muslim women in the context of the new Islamic hospitality industry by looking at the interactions between spiritual Islam and modern capitalism. We focus on the consumption process of the female customers of these hotels as part of defining and redefining their newly developing identity that is Islamic and spiritual; as well as modern and luxurious. The study responds to the call of Gökarıksel and Secor to analyse new Islamic patterns of consumption and leisure by building on their perspectives bridging neoliberal capitalism and resurgence of Islamic identities. We call for a critical and contextual perspective to understand the dynamic emergence of new forms of Islamic lifestyles and capitalism; emphasising a future agenda of further research that is sensitive to the complexities of desires and leisure activities of veiled Muslim women in diverse countries

    Two specific mutations are prevalent causes of recessive retinitis pigmentosa in North American patients of Jewish ancestry.

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    PURPOSE: Retinitis pigmentosa is a Mendelian disease with a very elevated genetic heterogeneity. Most mutations are responsible for less than 1% of cases, making molecular diagnosis a multigene screening procedure. In this study, we assessed whether direct testing of specific alleles could be a valuable screening approach in cases characterized by prevalent founder mutations. METHODS: We screened 275 North American patients with recessive/isolate retinitis pigmentosa for two mutations: an Alu insertion in the MAK gene and the p.Lys42Glu missense in the DHDDS gene. All patients were unrelated; 35 reported Jewish ancestry and the remainder reported mixed ethnicity. RESULTS: We identified the MAK and DHDDS mutations homozygously in only 2.1% and 0.8%, respectively, of patients of mixed ethnicity, but in 25.7% and 8.6%, respectively, of cases reporting Jewish ancestry. Haplotype analyses revealed that inheritance of the MAK mutation was attributable to a founder effect. CONCLUSION: In contrast to most mutations associated with retinitis pigmentosa-which are, in general, extremely rare-the two alleles investigated here cause disease in approximately one-third of North American patients reporting Jewish ancestry. Therefore, their screening constitutes an alternative procedure to large-scale tests for patients belonging to this ethnic group, especially in time-sensitive situations.Genet Med 17 4, 285-290
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