Laminar Spirals in the Outer Stationary Cylinder Couette-Taylor System

We present numerical simulations to demonstrate the existence of laminar spiral flows between both finite and infinite length concentric cylinders and finite truncated cones where only the inner wall rotates. The velocities and pressure are calculated by a spectral element/Fourier method. Different gap ratios are investigated. Convergence of the numerical results is shown with reference to flows between infinite cylinders. The presence of top and bottom endplates results in vortex dislocations that are observed at the frontiers between the Ekman vortices present at each end and the spiral vortices

The importance of moisture distribution for the growth and energetics of mid-latitude systems

A primitive equation model is used to study the sensitivity of baroclinic wave life cycles to the initial latitude-height distribution of humidity. Diabatic heating is parametrized only as a consequence of condensation in regions of large-scale ascent. Experiments are performed in which the initial relative humidity is a simple function of model level, and in some cases latitude bands are specified which are initially relatively dry. It is found that the presence of moisture can either increase or decrease the peak eddy kinetic energy of the developing wave, depending on the initial moisture distribution. A relative abundance of moisture at mid-latitudes tends to weaken the wave, while a relative abundance at low latitudes tends to strengthen it. This sensitivity exists because competing processes are at work. These processes are described in terms of energy box diagnostics. The most realistic case lies on the cusp of this sensitivity. Further physical parametrizations are then added, including surface fluxes and upright moist convection. These have the effect of increasing wave amplitude, but the sensitivity to initial conditions of relative humidity remains. Finally, 'control' and 'doubled CO2' life cycles are performed, with initial conditions taken from the time-mean zonal-mean output of equilibrium GCM experiments. The attenuation of the wave resulting from reduced baroclinicity is more pronounced than any effect due to changes in initial moisture

No Evidence for Orbital Loop Currents in Charge Ordered YBa2_2Cu3_3O6+x_{6+x} from Polarized Neutron Diffraction

It has been proposed that the pseudogap state of underdoped cuprate superconductors may be due to a transition to a phase which has circulating currents within each unit cell. Here, we use polarized neutron diffraction to search for the corresponding orbital moments in two samples of underdoped YBa$_2$Cu$_3$O$_{6+x}$ with doping levels $p=0.104$ and 0.123. In contrast to some other reports using polarized neutrons, but in agreement with nuclear magnetic resonance and muon spin rotation measurements, we find no evidence for the appearance of magnetic order below 300 K. Thus, our experiment suggests that such order is not an intrinsic property of high-quality cuprate superconductor single crystals. Our results provide an upper bound for a possible orbital loop moment which depends on the pattern of currents within the unit cell. For example, for the CC-$\theta_{II}$ pattern proposed by Varma, we find that the ordered moment per current loop is less than 0.013 $\mu_B$ for $p=0.104$.Comment: Comments in arXiv:1710.08173v1 fully addresse

Competing charge, spin, and superconducting orders in underdoped YBa2Cu3Oy

To explore the doping dependence of the recently discovered charge density wave (CDW) order in YBa2Cu3Oy, we present a bulk-sensitive high-energy x-ray study for several oxygen concentrations, including strongly underdoped YBa2Cu3O6.44. Combined with previous data around the so-called 1/8 doping, we show that bulk CDW order exists at least for hole concentrations (p) in the CuO2 planes of 0.078 <~ p <~ 0.132. This implies that CDW order exists in close vicinity to the quantum critical point for spin density wave (SDW) order. In contrast to the pseudogap temperature T*, the onset temperature of CDW order decreases with underdoping to T_CDW ~ 90K in YBa2Cu3O6.44. Together with a weakened order parameter this suggests a competition between CDW and SDW orders. In addition, the CDW order in YBa2Cu3O6.44 shows the same type of competition with superconductivity as a function of temperature and magnetic field as samples closer to p = 1/8. At low p the CDW incommensurability continues the previously reported linear increasing trend with underdoping. In the entire doping range the in-plane correlation length of the CDW order in b-axis direction depends only very weakly on the hole concentration, and appears independent of the type and correlation length of the oxygen-chain order. The onset temperature of the CDW order is remarkably close to a temperature T^\dagger that marks the maximum of 1/(T_1T) in planar 63^Cu NQR/NMR experiments, potentially indicating a response of the spin dynamics to the formation of the CDW. Our discussion of these findings includes a detailed comparison to the charge stripe order in La2-xBaxCuO4.Comment: 11 pages, 5 figure

Automated image analysis to improve bead ingestion toxicity test counts in the protozoan Tetrahymena pyriformis

Prova de tipográfica (In Press).Aims: To improve bead ingestion counts in Tetrahymena pyriformis by automated image analysis as an alternative to direct-counts. Methods and Results: Fluorescent latex beads were added to T. pyriformis cultures for ingestion tests. The number of beads ingested by 25 cells was counted directly by epifluorescence microscopy and compared with similar data from image analysis. ANOVA indicated that counts were not significantly different (P < 0.05). The image analysis particularly provided advantages in terms of speed. Conclusions: The image analysis is superior to direct beads counting in T. pyriformis particularly in terms of speed of analysis. Significance and Impact of the Study: The image analysis method is very rapid and will allow many more toxicological analyses to be undertaken with less operator error

High-Reynolds-number wall-modelled large eddy simulations of turbulent pipe flows using explicit and implicit subgrid stress treatments within a spectral element solver

We present explicit and implicit large eddy simulations for fully developed turbulent pipe flows using a continuous-Galerkin spectral element solver. On the one hand, the explicit stretched-vortex model (by Misra & Pullin [45] and Chung & Pullin [14]), accounts for an explicit treatment of unresolved stresses and is adapted to the high-order solver. On the other hand, an implicit approach based on a spectral vanishing viscosity technique is implemented. The latter implicit technique is modified to incorporate Chung & Pullin virtual-wall model instead of relying on implicit dissipative mechanisms near walls. This near-wall model is derived by averaging in the wall-normal direction and relying in local inner scaling to treat the time-dependence of the filtered wall-parallel velocity. The model requires space-time varying Dirichlet and Neumann boundary conditions for velocity and pressure respectively. We provide results and comparisons for the explicit and implicit subgrid treatments and show that both provide favourable results for pipe flows at Re_τ = 2×10^3 and Re_τ = 1.8×10^5 in terms of turbulence statistics. Additionally, we conclude that implicit simulations are enhanced when including the wall model and provide the correct statistics near walls

The nature of the charge density waves in under-doped YBa2_2Cu3_3O6.54_{6.54} revealed by X-ray measurements of the ionic displacements

All underdoped high-temperature cuprate superconductors appear to exhibit charge density wave (CDW) order, but both the underlying symmetry breaking and the origin of the CDW remain unclear. We use X-ray diffraction to determine the microscopic structure of the CDW in an archetypical cuprate YBa$_2$Cu$_3$O$_{6.54}$ at its superconducting transition temperature Tc ~ 60 K. We find that the CDWs present in this material break the mirror symmetry of the CuO2 bilayers. The ionic displacements in a CDW have two components: one perpendicular to the CuO$_2$ planes, and another parallel to these planes, which is out of phase with the first. The largest displacements are those of the planar oxygen atoms and are perpendicular to the CuO$_2$ planes. Our results allow many electronic properties of the underdoped cuprates to be understood. For instance, the CDW will lead to local variations in the doping (or electronic structure) giving an explicit explanation of the appearance of density-wave states with broken symmetry in scanning tunnelling microscopy (STM) and soft X-ray measurements

High-Reynolds-number wall-modelled large eddy simulations of turbulent pipe flows using explicit and implicit subgrid stress treatments within a spectral element solver

We present explicit and implicit large eddy simulations for fully developed turbulent pipe flows using a continuous-Galerkin spectral element solver. On the one hand, the explicit stretched-vortex model (by Misra & Pullin [45] and Chung & Pullin [14]), accounts for an explicit treatment of unresolved stresses and is adapted to the high-order solver. On the other hand, an implicit approach based on a spectral vanishing viscosity technique is implemented. The latter implicit technique is modified to incorporate Chung & Pullin virtual-wall model instead of relying on implicit dissipative mechanisms near walls. This near-wall model is derived by averaging in the wall-normal direction and relying in local inner scaling to treat the time-dependence of the filtered wall-parallel velocity. The model requires space-time varying Dirichlet and Neumann boundary conditions for velocity and pressure respectively. We provide results and comparisons for the explicit and implicit subgrid treatments and show that both provide favourable results for pipe flows at Re_τ = 2×10^3 and Re_τ = 1.8×10^5 in terms of turbulence statistics. Additionally, we conclude that implicit simulations are enhanced when including the wall model and provide the correct statistics near walls

New insights into the size and stoichiometry of the plasminogen activator inhibitor type-1·vitronectin complex

Plasminogen activator inhibitor-type 1 (PAI-1) is the primary inhibitor of endogenous plasminogen activators that generate plasmin in the vicinity of a thrombus to initiate thrombolysis, or in the pericellular region of cells to facilitate migration and/or tissue remodeling. It has been shown that the physiologically relevant form of PAI-1 is in a complex with the abundant plasma glyco-protein, vitronectin. The interaction between vitronectin and PAI-1 is important for stabilizing the inhibitor in a reactive conformation. Although the complex is clearly significant, information is vague regarding the composition of the complex and consequences of its formation on the distribution and activity of vitronectin in vivo. Most studies have assumed a 1:1 interaction between the two proteins, but this has not been demonstrated experimentally and is a matter of some controversy since more than one PAI-1-binding site has been proposed within the sequence of vitronectin. To address this issue, competition studies using monoclonal antibodies specific for separate epitopes confirmed that the two distinct PAI-1-binding sites present on vitronectin can be occupied simultaneously. Analytical ultracentrifugation was used also for a rigorous analysis of the composition and sizes of complexes formed from purified vitronectin and PAI-1. The predominant associating species observed was high in molecular weight (M(r) ~ 320,000), demonstrating that self-association of vitronectin occurs upon interaction with PAI-1. Moreover, the size of this higher order complex indicates that two molecules of PAI-1 bind per vitronectin molecule. Binding of PAI-1 to vitronectin and association into higher order complexes is proposed to facilitate interaction with macromolecules on surfaces