5,294 research outputs found

    Beyond Documentation: 3D Data in Archaeology

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    As the costs associated with the collection of 3D data continue to plummet, there is little doubt that the number of available archaeology-related 3D datasets will increase dramatically in the coming decade. While our analytical procedures continue to evolve as new applications are contemplated, analyses of 3D data are increasing in frequency within the archaeological literature. In this article, we seek to provide a brief overview of a few examples from our own research and explore some possibilities that may add value to existing collections. In the following pages, we discuss some of the ways that 3D data have been used in studies of morphometrics, public archaeology, excavation, and comparative endeavors

    Structure and Vibrations of the Vicinal Copper (211) Surface

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    We report a first principles theoretical study of the surface relaxation and lattice dynamics of the Cu(211) surface using the plane wave pseudopotential method. We find large atomic relaxations for the first several atomic layers near the step edges on this surface, and a substantial step-induced renormalization of the surface harmonic force constants. We use the results to study the harmonic fluctuations around the equilibrium structure and find three new step-derived features in the zone center vibrational spectrum. Comparison of these results with previous theoretical work and weith experimental studies using inelastic He scattering are reported.Comment: 6 Pages RevTex, 7 Figures in Postscrip

    A powerful intervention: general practitioners' use of sickness certification in depression

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    <b>Background</b> Depression is frequently cited as the reason for sickness absence, and it is estimated that sickness certificates are issued in one third of consultations for depression. Previous research has considered GP views of sickness certification but not specifically in relation to depression. This study aimed to explore GPs views of sickness certification in relation to depression.<p></p> <b>Methods</b> A purposive sample of GP practices across Scotland was selected to reflect variations in levels of incapacity claimants and antidepressant prescribing. Qualitative interviews were carried out between 2008 and 2009.<p></p> <b>Results</b> A total of 30 GPs were interviewed. A number of common themes emerged including the perceived importance of GP advocacy on behalf of their patients, the tensions between stakeholders involved in the sickness certification system, the need to respond flexibly to patients who present with depression and the therapeutic nature of time away from work as well as the benefits of work. GPs reported that most patients with depression returned to work after a short period of absence and that it was often difficult to predict which patients would struggle to return to work.<p></p> <b>Conclusions</b> GPs reported that dealing with sickness certification and depression presents distinct challenges. Sickness certificates are often viewed as powerful interventions, the effectiveness of time away from work for those with depression should be subject to robust enquiry

    Occasional Publications of the Bounds Law Library, Number Five: Commonplace Books of Law: A Selection of Law-Related Notebooks

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    Occasional Publications of the Bounds Law Library, Number Five contains the transcriptions of five notebooks, one ledger, and one diary as well as critical introductions to each piece and an essay on notebooks in legal culture. Primary sources include: a seventeenth century notebook authored by multiple anonymous persons likely to have been students in the Inns of Courts, Alexander Dorcas\u27 ledger used from 1785 to 1817, George Josiah Sturges Walker\u27s 1826 Litchfield Law School notebook, Thomas K. Jackson\u27s 1871 diary, James Thomas Kirk\u27s notebook used from 1891 to 1916, Jerome T. Fuller\u27s notebook used from 1925 to 1935, and Hugo L. Black\u27s notebook used from 1938 to 1940.https://scholarship.law.ua.edu/occasional_publications/1004/thumbnail.jp

    Trial Protocol: Randomised controlled trial of the effects of very low calorie diet, modest dietary restriction, and sequential behavioural programme on hunger, urges to smoke, abstinence and weight gain in overweight smokers stopping smoking

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    Background\ud Weight gain accompanies smoking cessation, but dieting during quitting is controversial as hunger may increase urges to smoke. This is a feasibility trial for the investigation of a very low calorie diet (VLCD), individual modest energy restriction, and usual advice on hunger, ketosis, urges to smoke, abstinence and weight gain in overweight smokers trying to quit. \ud \ud Methods\ud This is a 3 armed, unblinded, randomized controlled trial in overweight (BMI > 25 kg/m2m^2), daily smokers (CO > 10 ppm); with at least 30 participants in each group. Each group receives identical behavioural support and NRT patches (25 mg(8 weeks),15 mg(2 weeks),10 mg(2 weeks)). The VLCD group receive a 429-559 kcal/day liquid formula beginning 1 week before quitting and continuing for 4 weeks afterwards. The modest energy restricted group (termed individual dietary and activity planning(IDAP)) engage in goal-setting and receive an energy prescription based on individual basal metabolic rate(BMR) aiming for daily reduction of 600 kcal. The control group receive usual dietary advice that accompanies smoking cessation i.e. avoiding feeling hungry but eating healthy snacks. After this, the VLCD participants receive IDAP to provide support for changing eating habits in the longer term; the IDAP group continues receiving this support. The control group receive IDAP 8 weeks after quitting. This allows us to compare IDAP following a successful quit attempt with dieting concurrently during quitting. It also aims to prevent attrition in the unblinded, control group by meeting their need for weight management. Follow-up occurs at 6 and 12 months. \ud \ud Outcome measures include participant acceptability, measured qualitatively by semi-structured interviewing and quantitatively by recruitment and attrition rates. Feasibility of running the trial within primary care is measured by interview and questionnaire of the treatment providers. Adherence to the VLCD is verified by the presence of urinary ketones measured weekly. Daily urges to smoke, hunger and withdrawal are measured using the Mood and Physical Symptoms Scale-Combined (MPSS-C) and a Hunger Craving Score (HCS). 24 hour, 7 day point prevalence and 4-week prolonged abstinence (Russell Standard) is confirmed by CO < 10 ppm. Weight, waist and hip circumference and percentage body fat are measured at each visit. \ud \ud Trial Registration\ud Current controlled trials ISRCTN83865809\ud \u

    Communications Biophysics

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    Contains reports on five research projects.National Science Foundation (Grant G-16526)National Institutes of Health (Grant MH-04737-02

    Phase diagram of the S=1/2 quantum spin chain with bond alternation

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    We study the ground state properties of the bond alternating S=1/2S=1/2 quantum spin chain whose Hamiltonian is H=\sum_j (S_{2j}^x S_{2j+1}^x +S_{2j}^y S_{2j+1}^y +\lambda S_{2j}^z S_{2j+1}^z ) +\beta \sum_j {\bf S}_{2j-1} \cdot {\bf S}_{2j} . When β=0\beta=0, the ground state is a collection of local singlets with a finite excitation gap. In the limit of strong ferromagnetic coupling β\beta \to - \infty, this is equivalent to the S=1 XXZS=1 \ XXZ Hamiltonian. It has several ground state phases in the λ\lambda-β\beta plane including the gapful Haldane phase. They are characterized by a full breakdown, partial breakdowns and a non-breakdown of the hidden discrete Z2×Z2Z_2 \times Z_2 symmetry. The ground state phase diagram is obtained by series expansions.Comment: 25 pages, RevTex 2.0, 9 Figures available on request, Tec.rep. of ISSP No.A265

    Muscle metabolic and neuromuscular determinants of fatigue during cycling in different exercise intensity domains.

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    Lactate or gas exchange threshold (GET) and critical power (CP) are closely associated with human exercise performance. We tested the hypothesis that the limit of tolerance (Tlim) during cycle exercise performed within the exercise intensity domains demarcated by GET and CP is linked to discrete muscle metabolic and neuromuscular responses. Eleven men performed a ramp incremental exercise test, 4-5 severe-intensity (SEV; >CP) constant-work-rate (CWR) tests until Tlim, a heavy-intensity (HVY; GET) CWR test until Tlim, and a moderate-intensity (MOD; 0.05) muscle metabolic milieu (i.e., low pH and [PCr] and high [lactate]) was attained at Tlim (approximately 2-14 min) for all SEV exercise bouts. The muscle metabolic perturbation was greater at Tlim following SEV compared with HVY, and also following SEV and HVY compared with MOD (all P 0.05). Neural drive to the VL increased during SEV (4 ± 4%; P 0.05). During SEV and HVY, but not MOD, the rates of change in M-wave amplitude and neural drive were correlated with changes in muscle metabolic ([PCr], [lactate]) and blood ionic/acid-base status ([lactate], [K(+)]) (P < 0.05). The results of this study indicate that the metabolic and neuromuscular determinants of fatigue development differ according to the intensity domain in which the exercise is performed.NEW & NOTEWORTHY The gas exchange threshold and the critical power demarcate discrete exercise intensity domains. For the first time, we show that the limit of tolerance during whole-body exercise within these domains is characterized by distinct metabolic and neuromuscular responses. Fatigue development during exercise greater than critical power is associated with the attainment of consistent "limiting" values of muscle metabolites, whereas substrate availability and limitations to muscle activation may constrain performance at lower intensities
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