Sharing Stress With a Robot: What Would a Robot Say?

With the prevalence of mental health problems today, designing human-robot interaction for mental health intervention is not only possible, but critical. The current experiment examined how three types of robot disclosure (emotional, technical, and by-proxy) affect robot perception and human disclosure behavior during a stress-sharing activity. Emotional robot disclosure resulted in the lowest robot perceived safety. Post-hoc analysis revealed that increased perceived stress predicted reduced human disclosure, user satisfaction, robot likability, and future robot use. Negative attitudes toward robots also predicted reduced intention for future robot use. This work informs on the possible design of robot disclosure, as well as how individual attributes, such as perceived stress, can impact human robot interaction in a mental health context

Anger without Agency: Exploring the Experiences of Stress in Adolescent Girls

Although a great deal of research has measured stressful life events and stress-related symptoms in adolescents, little research has qualitatively examined the experience of stress in teens. The purpose of this study was to utilize thematic analysis to explore how teen girls described their experiences of stress. Thirty-one girls, ages 14–18, were recruited for a study examining stress and stress-related symptoms. As part of this study, they participated in an open-ended, qualitative interview about their personal experiences of stress. Themes included the mind of stress, emotionally shutting out others, and “growing out of it.” The overarching finding was that all teen girls described anger in relation to stress. Most concerning was the predominant theme of a lack of agency in relation to affecting change or management of stress in their lives

Doubly connected minimal surfaces and extremal harmonic mappings

The concept of a conformal deformation has two natural extensions: quasiconformal and harmonic mappings. Both classes do not preserve the conformal type of the domain, however they cannot change it in an arbitrary way. Doubly connected domains are where one first observes nontrivial conformal invariants. Herbert Groetzsch and Johannes C. C. Nitsche addressed this issue for quasiconformal and harmonic mappings, respectively. Combining these concepts we obtain sharp estimates for quasiconformal harmonic mappings between doubly connected domains. We then apply our results to the Cauchy problem for minimal surfaces, also known as the Bjorling problem. Specifically, we obtain a sharp estimate of the modulus of a doubly connected minimal surface that evolves from its inner boundary with a given initial slope.Comment: 35 pages, 2 figures. Minor edits, references adde

Multicenter data acquisition made easy

<p>Abstract</p> <p>Background</p> <p>The process for data collection in multicenter trials may be troublesome and expensive. We report our experience with the spreadsheet function in Googledocs for this purpose.</p> <p>Methods</p> <p>In Googledocs the data manager creates a form similar to the paper case record form, which will function as a decentral data entry module. When the forms are submitted, they are presented in a spreadsheet in Googledocs, which can be exported to different standard spreadsheet formats.</p> <p>Results</p> <p>For a multicenter randomized clinical trial with five different participating hospitals we created a decentral data entry module using the spreadsheet function in Googledocs. The study comprised 332 patients (clinicaltrials.gov identifier: NCT00815698) with five visits per patient. One person at each study site entered data from the original paper based case report forms which were kept at the study sites as originals. We did not experience any technical problems using the system.</p> <p>Conclusions</p> <p>The system allowed for decentral data entry, and it was easy to use, safe, and free of charge. The spreadsheet function in Googledocs may potentially replace current expensive solutions for data acquisition in multicenter trials.</p> <p>Trial registration</p> <p>clinicaltrials.gov NCT00815698</p

Investigating the Electromechanical Behavior of Unconventionally Ferroelectric Hf0.5Zr0.5O2-Based Capacitors Through Operando Nanobeam X-Ray Diffraction

Understanding various aspects of ferroelectricity in hafnia-based nanomaterials is of vital importance for the development of future nonvolatile memory and logic devices. Here, the unconventional and weak electromechanical response of epitaxial La0.67Sr0.33MnO3/Hf0.5Zr0.5O2/La0.67Sr0.33MnO3 ferroelectric capacitors is investigated, via the sensitivity offered by nanobeam X-ray diffraction experiments during application of electrical bias. It is shown that the pristine rhombohedral phase exhibits a linear piezoelectric effect with piezoelectric coefficient (|d33|) ≈ 0.5–0.8 pmV−1. It is found that the piezoelectric response is suppressed above the coercive voltage. For higher voltages, and with the onset of DC conductivity throughout the capacitor, a second-order effect is observed. The work sheds light into the electromechanical response of rhombohedral Hf0.5Zr0.5O2 and suggests its (un)correlation with ferroelectric switching

Distance in audio for VR: Constraints and opportunities

Spatial audio is enjoying a surge in attention in both scene and object based paradigms, due to the trend for, and accessibility of, immersive experience. This has been enabled through convergence in computing enhancements, component size reduction, and associated price reductions. For the first time, applications such as virtual reality (VR) are technologies for the consumer. Audio for VR is captured to provide a counterpart to the video or animated image, and can be rendered to combine elements of physical and psychoacoustic modelling, as well as artistic design. Given that distance is an inherent property of spatial audio, that it can augment sound's efficacy in cueing user attention (a problem which practitioners are seeking to solve), and that conventional film sound practices have intentionally exploited its use, the absence of research on its implementation and effects in immersive environments is notable. This paper sets out the case for its importance, from a perspective of research and practice. It focuses on cinematic VR, whose challenges for spatialized audio are clear, and at times stretches beyond the restrictions specific to distance in audio for VR, into more general audio constraints

Structural photoactivation of a full-length bacterial phytochrome

Phytochromes are light sensor proteins found in plants, bacteria, and fungi. They function by converting a photon absorption event into a conformational signal that propagates from the chromophore through the entire protein. However, the structure of the photoactivated state and the conformational changes that lead to it are not known. We report time-resolved x-ray scattering of the full-length phytochrome from Deinococcus radiodurans on micro- and millisecond time scales. We identify a twist of the histidine kinase output domains with respect to the chromophore-binding domains as the dominant change between the photoactivated and resting states. The time-resolved data further show that the structural changes up to the microsecond time scales are small and localized in the chromophore-binding domains. The global structural change occurs within a few milliseconds, coinciding with the formation of the spectroscopic meta-Rc state. Our findings establish key elements of the signaling mechanism of full-length bacterial phytochromes

Scalable In Situ Hybridization on Tissue Arrays for Validation of Novel Cancer and Tissue-Specific Biomarkers

Tissue localization of gene expression is increasingly important for accurate interpretation of large scale datasets from expression and mutational analyses. To this end, we have (1) developed a robust and scalable procedure for generation of mRNA hybridization probes, providing >95% first-pass success rate in probe generation to any human target gene and (2) adopted an automated staining procedure for analyses of formalin-fixed paraffin-embedded tissues and tissue microarrays. The in situ mRNA and protein expression patterns for genes with known as well as unknown tissue expression patterns were analyzed in normal and malignant tissues to assess procedure specificity and whether in situ hybridization can be used for validating novel antibodies. We demonstrate concordance between in situ transcript and protein expression patterns of the well-known pathology biomarkers KRT17, CHGA, MKI67, PECAM1 and VIL1, and provide independent validation for novel antibodies to the biomarkers BRD1, EZH2, JUP and SATB2. The present study provides a foundation for comprehensive in situ gene set or transcriptome analyses of human normal and tumor tissues