176 research outputs found
Time separation as a hidden variable to the Copenhagen school of quantum mechanics
The Bohr radius is a space-like separation between the proton and electron in
the hydrogen atom. According to the Copenhagen school of quantum mechanics, the
proton is sitting in the absolute Lorentz frame. If this hydrogen atom is
observed from a different Lorentz frame, there is a time-like separation
linearly mixed with the Bohr radius. Indeed, the time-separation is one of the
essential variables in high-energy hadronic physics where the hadron is a bound
state of the quarks, while thoroughly hidden in the present form of quantum
mechanics. It will be concluded that this variable is hidden in Feynman's rest
of the universe. It is noted first that Feynman's Lorentz-invariant
differential equation for the bound-state quarks has a set of solutions which
describe all essential features of hadronic physics. These solutions explicitly
depend on the time separation between the quarks. This set also forms the
mathematical basis for two-mode squeezed states in quantum optics, where both
photons are observable, but one of them can be treated a variable hidden in the
rest of the universe. The physics of this two-mode state can then be translated
into the time-separation variable in the quark model. As in the case of the
un-observed photon, the hidden time-separation variable manifests itself as an
increase in entropy and uncertainty.Comment: LaTex 10 pages with 5 figure. Invited paper presented at the
Conference on Advances in Quantum Theory (Vaxjo, Sweden, June 2010), to be
published in one of the AIP Conference Proceedings serie
Social class origin and assortative mating in Britain, 1949-2010
This article examines trends in assortative mating in Britain over the last 60 years. Assortative mating is the tendency for like to form a conjugal partnership with like. Our focus is on the association between the social class origins of the partners. The propensity towards assortative mating is taken as an index of the openness of society which we regard as a macro level aspect of social inequality. There is some evidence that the propensity for partners to come from similar class backgrounds declined during the 1960s. Thereafter, there was a period of 40 years of remarkable stability during which the propensity towards assortative mating fluctuated trendlessly within quite narrow limits. This picture of stability over time in social openness parallels the well-established facts about intergenerational social class mobility in Britain
Brain data:Scanning, scraping and sculpting the plastic learning brain through neurotechnology
Neurotechnology is an advancing field of research and development with significant implications for education. As 'postdigital' hybrids of biological and informational codes, novel neurotechnologies combine neuroscience insights into the human brain with advanced technical development in brain imaging, brain-computer interfaces, neurofeedback platforms, brain stimulation and other neuroenhancement applications. Merging neurobiological knowledge about human life with computational technologies, neurotechnology exemplifies how postdigital science will play a significant role in societies and education in decades to come. As neurotechnology developments are being extended to education, they present potential for businesses and governments to enact new techniques of 'neurogovernance' by 'scanning' the brain, 'scraping' it for data and then 'sculpting' the brain toward particular capacities. The aim of this article is to critically review neurotechnology developments and implications for education. It examines the purposes to which neurotechnology development is being put in education, interrogating the commercial and governmental objectives associated with it and the neuroscientific concepts and expertise that underpin it. Finally, the article raises significant ethical and governance issues related to neurotechnology development and postdigital science that require concerted attention from education researchers
Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells
<p>Abstract</p> <p>Background</p> <p>Primary cilia are non-motile sensory cytoplasmic organelles that have been implicated in signal transduction, cell to cell communication, left and right pattern embryonic development, sensation of fluid flow, regulation of calcium levels, mechanosensation, growth factor signaling and cell cycle progression. Defects in the formation and/or function of these structures underlie a variety of human diseases such as Alström, Bardet-Biedl, Joubert, Meckel-Gruber and oral-facial-digital type 1 syndromes. The expression and function of primary cilia in cancer cells has now become a focus of attention but has not been studied in astrocytomas/glioblastomas. To begin to address this issue, we compared the structure and expression of primary cilia in a normal human astrocyte cell line with five human astrocytoma/glioblastoma cell lines.</p> <p>Methods</p> <p>Cultured normal human astrocytes and five human astrocytoma/glioblastoma cell lines were examined for primary cilia expression and structure using indirect immunofluorescence and electron microscopy. Monospecific antibodies were used to detect primary cilia and map the relationship between the primary cilia region and sites of endocytosis.</p> <p>Results</p> <p>We show that expression of primary cilia in normal astrocytes is cell cycle related and the primary cilium extends through the cell within a unique structure which we show to be a site of endocytosis. Importantly, we document that in each of the five astrocytoma/glioblastoma cell lines fully formed primary cilia are either expressed at a very low level, are completely absent or have aberrant forms, due to incomplete ciliogenesis.</p> <p>Conclusions</p> <p>The recent discovery of the importance of primary cilia in a variety of cell functions raises the possibility that this structure may have a role in a variety of cancers. Our finding that the formation of the primary cilium is disrupted in cells derived from astrocytoma/glioblastoma tumors provides the first evidence that altered primary cilium expression and function may be part of some malignant phenotypes. Further, we provide the first evidence that ciliogenesis is not an all or none process; rather defects can arrest this process at various points, particularly at the stage subsequent to basal body association with the plasma membrane.</p
Families’ roles in children’s literacy in the UK throughout the 20th century
This paper explores the changing roles of families in children’s developing literacy in the UK in the last century. It discusses how, during this time, understandings of reading and writing have evolved into the more nuanced notion of literacy. Further, in acknowledging changes in written communication practices, and shifting attitudes to reading and writ- ing, the paper sketches out how families have always played some part in the literacy of younger generations; though reading was frequently integral to the lives of many families throughout the past century, we consider in particular the more recent enhancement of children’s literacy through targeted family programmes. The paper considers policy implications for promoting young children’s literacy through work with families
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The physiological responses of cacao to the environment and the implications for climate change resilience. A review
Cacao (Theobroma cacao L.) is a tropical perennial crop which is of great economic importance to the confectionary industry and to the economies of many countries of the humid tropics where it is grown. Some recent studies have suggested climate change could severely impact cacao production in West Africa. It is essential to incorporate our understanding of the physiology and genetic variation within cacao germplasm when discussing the implications of climate change on cacao productivity and developing strategies for climate resilience in cacao production.
Here we review the current research on the physiological responses of cacao to various climate factors. Our main findings are 1) water limitation causes significant yield reduction in cacao but genotypic variation in sensitivity is evident, 2) in the field cacao experiences higher temperatures than is often reported in the literature, 3) the complexity of the cacao/ shade tree interaction can lead to contradictory results, 4) elevated CO2 may alleviate some negative effects of climate change 5) implementation of mitigation strategies can help reduce environmental stress, 6) significant gaps in the research need addressing to accelerate the development of climate resilience. Harnessing the significant genetic variation apparent within cacao germplasm is essential to develop modern varieties capable of high yields in non-optimal conditions. Mitigation strategies will also be essential but to use shading to best effect shade tree selection is crucial to avoid resource competition. Cacao is often described as being sensitive to climate change but genetic variation, adaptive responses, appropriate mitigation strategies and interactive climate effects should all be considered when predicting the future of cacao production. Incorporating these physiological responses to various environmental conditions and developing a deeper understanding of the processes underlying these responses will help to accelerate the development of a more resource use efficient tree ensuring sustainable production into the future
The Flux-Line Lattice in Superconductors
Magnetic flux can penetrate a type-II superconductor in form of Abrikosov
vortices. These tend to arrange in a triangular flux-line lattice (FLL) which
is more or less perturbed by material inhomogeneities that pin the flux lines,
and in high- supercon- ductors (HTSC's) also by thermal fluctuations. Many
properties of the FLL are well described by the phenomenological
Ginzburg-Landau theory or by the electromagnetic London theory, which treats
the vortex core as a singularity. In Nb alloys and HTSC's the FLL is very soft
mainly because of the large magnetic penetration depth: The shear modulus of
the FLL is thus small and the tilt modulus is dispersive and becomes very small
for short distortion wavelength. This softness of the FLL is enhanced further
by the pronounced anisotropy and layered structure of HTSC's, which strongly
increases the penetration depth for currents along the c-axis of these uniaxial
crystals and may even cause a decoupling of two-dimensional vortex lattices in
the Cu-O layers. Thermal fluctuations and softening may melt the FLL and cause
thermally activated depinning of the flux lines or of the 2D pancake vortices
in the layers. Various phase transitions are predicted for the FLL in layered
HTSC's. The linear and nonlinear magnetic response of HTSC's gives rise to
interesting effects which strongly depend on the geometry of the experiment.Comment: Review paper for Rep.Prog.Phys., 124 narrow pages. The 30 figures do
not exist as postscript file
Shattered pellet injection experiments at JET in support of the ITER disruption mitigation system design
A series of experiments have been executed at JET to assess the efficacy of the newly installed shattered pellet injection (SPI) system in mitigating the effects of disruptions. Issues, important for the ITER disruption mitigation system, such as thermal load mitigation, avoidance of runaway electron (RE) formation, radiation asymmetries during thermal quench mitigation, electromagnetic load control and RE energy dissipation have been addressed over a large parameter range. The efficiency of the mitigation has been examined for the various SPI injection strategies. The paper summarises the results from these JET SPI experiments and discusses their implications for the ITER disruption mitigation scheme
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