A HARDWAREINTHELOOP SIMULATOR BASED ON REAL SKODA SUPERB VEHICLE AND RTLAB/CARSIM

This paper describes the design and realization of a hardware-in-the-loop simulator made from a real Skoda Superb vehicle. A combination of RT-LAB and CarSim software is used for real-time control and for handling the sensoric subsystems. The simulator provides almost realistic testing of driving cycles with on-line visualization. This unique device can be used in various fields of research

A HARDWARE-IN-THE-LOOP SIMULATOR BASED ON REAL SKODA SUPERB VEHICLE AND RT-LAB/CARSIM

This paper describes the design and realization of a hardware-in-the-loop simulator made from a real Skoda Superb vehicle. A combination of RT-LAB and CarSim software is used for real-time control and for handling the sensoric subsystems. The simulator provides almost realistic testing of driving cycles with on-line visualization. This unique device can be used in various fields of research

Studium vzácných rozpadů B-mesonů v experimentu ATLAS

Jedným z fyzikálnych kanálov testujúcich predpovede Štandard- ného modelu častíc na experimente ATLAS je vzácny rozpad B0 d → K∗ µ− µ+ . Táto práca slúži ako jeden z podkladov pre analýzu tohto rozpadu v období na- berania dát Run 2. Konkrétne sa v nej zaoberáme hľadaním popisu rozdelenia invariantných hmotností B a K∗ mezónov a uhlového rozdelenia rozpadu pre sig- nálne dáta a pre známe druhy pozadia. Na fitovanie skúmaných rozdelení bola použitá metóda maximálnej vierohodnosti. Hľadanie popisujúcich funkcií hustoty pravdepodobnosti prebehlo na simulovaných dátach obsahujúcich signálny rozpad a hlavné pozaďové kanály (rozpady, o ktorých vieme, že ich detektor deteguje ako náš signálny rozpad), a to Bs → φ(K+ K− )µ+ µ− , Λb → Λ(1520)(pK− )µ+ µ− a Λb → pK− µ+ µ− . V prípade signálneho rozpadu boli oddelené prípady, kedy de- tektor deteguje signálny rozpad, ale nesprávne identifikuje dvojicu kaón a pión, čo spôsobí nepresné určenie ostatných parametrov. V prípade uhlového rozdele- nia sme navyše analyzovali aj kombinatorické pozadie z reálnych dát z Runu 1, ktorého popis v prípade invariantných hmotnosti neuvádzame pre jeho jednodu- chosť . Pre uhlové rozdelenia taktiež uvádzame porovnanie so spracovaním dát z Runu 1, kde sa namiesto novo-používaných sféricky harmonických funkcií použil zjednodušený...Rare B0 d → K∗ µ− µ+ decay is one of physics channels testing Stan- dard Model predictions at the ATLAS experiment. This work provides input to the future analysis of this rare decay in the data-taking period of Run 2. Speci- fically, in the work we were searching for the descriptions of the distributions of reconstructed invariant masses of the B and K∗ mesons and of the distribution of the decay angles for the signal decay and expected background processes. For the procedure of finding optimal description, a maximal likelihood method of fit was used. Search for the probability density functions was performed on simulated data containing signal decay and main the background channels (decays, which are misinterpreted by the detector like our signal decay). The background decays included Bs → φ(K+ K− )µ+ µ− , Λb → Λ(1520)(pK− )µ+ µ− and Λb → pK− µ+ µ− . The signal data were contamined with events, when detector misidentified the kaon and pion from the K∗ meson decay, which lead to modifications of the fit- ted parameters. These cases were separated and treated as special background process. In addition to the simulations, we analyzed the combinatorial background from the real data of Run 1, though only the angular distribution. Invariant mas- ses were not analyzed for their simplicity. We also show...Ústav částicové a jaderné fyzikyInstitute of Particle and Nuclear PhysicsMatematicko-fyzikální fakultaFaculty of Mathematics and Physic

Can Deep Learning Reliably Recognize Abnormality Patterns on Chest X-rays? A Multi-Reader Study Examining One Month of AI Implementation in Everyday Radiology Clinical Practice

In this study, we developed a deep-learning-based automatic detection algorithm (DLAD, Carebot AI CXR) to detect and localize seven specific radiological findings (atelectasis (ATE), consolidation (CON), pleural effusion (EFF), pulmonary lesion (LES), subcutaneous emphysema (SCE), cardiomegaly (CMG), pneumothorax (PNO)) on chest X-rays (CXR). We collected 956 CXRs and compared the performance of the DLAD with that of six individual radiologists who assessed the images in a hospital setting. The proposed DLAD achieved high sensitivity (ATE 1.000 (0.624-1.000), CON 0.864 (0.671-0.956), EFF 0.953 (0.887-0.983), LES 0.905 (0.715-0.978), SCE 1.000 (0.366-1.000), CMG 0.837 (0.711-0.917), PNO 0.875 (0.538-0.986)), even when compared to the radiologists (LOWEST: ATE 0.000 (0.000-0.376), CON 0.182 (0.070-0.382), EFF 0.400 (0.302-0.506), LES 0.238 (0.103-0.448), SCE 0.000 (0.000-0.634), CMG 0.347 (0.228-0.486), PNO 0.375 (0.134-0.691), HIGHEST: ATE 1.000 (0.624-1.000), CON 0.864 (0.671-0.956), EFF 0.953 (0.887-0.983), LES 0.667 (0.456-0.830), SCE 1.000 (0.366-1.000), CMG 0.980 (0.896-0.999), PNO 0.875 (0.538-0.986)). The findings of the study demonstrate that the suggested DLAD holds potential for integration into everyday clinical practice as a decision support system, effectively mitigating the false negative rate associated with junior and intermediate radiologists

Artificial Intelligence in Digital Art

The bachelor's thesis examines the contribution of artificial intelligence in the world of digital art, visual effects and filmmaking. In the theoretical part, the reader is taken through the development of digital art as such, the development of artificial intelligence in the artistic environment, how it works and what are the ethical and legal problems in this industry. In the practical part, a tool powered by artificial intelligence that generates new works of art is presented. They are used to analyze the ability to recognize content created by artificial intelligence and humans. Furthermore, the work examines to what extent artificial intelligence helps in this industry and whether it does not harm it more. The result of the work is an analysis of current technology, where it can move, what it means for artists and what are the possible risks.Bakalárska práca skúma prínos umelej inteligencie vo svete digitálneho umenia, vizuálnych efektov a filmovej tvorby. V teoretickej časti je čitateľ prevedený vývojom digitálneho umenia ako takého, vývojom umelej inteligencie v umeleckom prostredí, ako funguje a aké má etické a právne problémy v tomto odvetví. V praktickej časti je priblížený nástroj poháňaný umelou inteligenciou, ktorý generuje nové umelecké diela. Pomocou nich sa analyzuje schopnosť rozpoznávať obsah vytvorený umelou inteligenciou a človekom. Ďalej práca skúma v akom rozsahu pomáha umelá inteligencia v tomto odvetví a či jej viac neškodí. Výsledkom práce je analýza súčasnej technológie, kam sa môže posunúť, čo to znamená pre umelcov a aké sú možné riziká.Bakalářská práce zkoumá přínos umělé inteligence ve světě digitálního umění, vizuálních efektů a filmové tvorby. V teoretické části je čtenář proveden vývojem digitálního umění jako takového, vývojem umělé inteligence v uměleckém prostředí, jak funguje a jaké má etické a právní problémy v tomto odvětví. V praktické části je přiblížený nástroj poháněný umělou inteligencí, který generuje nová umělecká díla. Pomocí nich se analyzuje schopnost rozpoznávat obsah vytvořený umělou inteligencí a člověkem. Dále práce zkoumá v jakém rozsahu pomáhá umělá inteligence v tomto odvětví a zda jí víc neškodí. Výsledkem práce je analýza současné technologie, kam se může posunout, co to znamená pro umělce a jaká jsou možná rizika

Study of the rare B-meson decays with the ATLAS experiment

Title: Study of the rare B-meson decays with the ATLAS experiment Author: Marek Biroš Institute: Institute of Particle and Nuclear Physics Supervisor: RNDr. Pavel Řezníček, Ph.D., Institute of Particle and Nuclear Physics Abstract: The rare B0 d → K∗0 (892) μμ decay is one of the B-physics channels sensitive to Beyond Standard Model effects. The potential deviation from Standard Model predictions could be observed in the angular distribution of this decay. The work compiles several sub-tasks at the initial stage of this complex analysis: decay angles fit validation and signal event preselection. The fit functions used in the analysis are verified on generated toy Monte Carlo data. Ranges of parameters, for which are these functions positive, are established and within this parametric space, the testing of possible intrinsic fit biases is evaluated. A dependence of the fit bias with respect to the collected number of events (expected in Run 2 as well as at HL-LHC) and to the different signal-to- background ratio is studied. The second part of the thesis deals with processing of raw reconstructed data from the detector into n-tuples resulting in a more compact dataset that would be used in the final analysis. Within the process, baseline cuts are applied in order to minimize size of final datasets by reducing..

Studium vzácných rozpadů B-mesonů v experimentu ATLAS

Názov práce: Štúdium vzácných rozpadov B-mezónov v experimente ATLAS Author: Marek Biroš Ústav: Ústav částicové a jaderné fyziky Vedúci diplomovej práce: RNDr. Pavel Řezníček, Ph.D, Ústav částicové a jaderné fyziky Abstrakt: Štúdium vzácneho rozpadu B0 d → K∗0 (892) μμ má veľký potenciál pozorovať prejavy fyziky za Štandardným modelom, ktoré by sa mohli prejaviť v uhlovom rozdelení jeho produktov. Táto práca je zameraná na prípravu rôznych medzičlánkov, potrebných v počiatočnom štádiu zložitej analýzy rozpadu B0 d → K∗0(892) μμ a to konkrétne: validácia fitu uhlového rozdelenia a predvýber signálnych udalostí. Plánované fitovacie funkcie sú testované na generovaných toy Monte Carlo dátach. V rámci stanovených testovacích rozsahov, množine parametrov kde funkcia nadobúda iba kladné hodnoty pre všetky kombinácie uhlov, sú skúmané prejavy vnútorných skreslení, resp. vychýlení (tzv. biasov) fitu. Skúmaná bola najmä závislosť biasov na počte nameraných signálnych udalostí očakávaných v Rune 2 a v HL-LHC a na rôznom pomere signal-vs- pozadie. Ďalšou časťou bolo spolupodieľanie sa na rekonštrukcii predspracovaných dát z detektora do n-tuplov za účelom tvorby viac kompaktného datasetu, neskôr použitého v samotnej analýze. Pre efektívnejšiu redukciu veľkosti datasetu, boli aplikované základné výberové kritéria na...Title: Study of the rare B-meson decays with the ATLAS experiment Author: Marek Biroš Institute: Institute of Particle and Nuclear Physics Supervisor: RNDr. Pavel Řezníček, Ph.D., Institute of Particle and Nuclear Physics Abstract: The rare B0 d → K∗0 (892) μμ decay is one of the B-physics channels sensitive to Beyond Standard Model effects. The potential deviation from Standard Model predictions could be observed in the angular distribution of this decay. The work compiles several sub-tasks at the initial stage of this complex analysis: decay angles fit validation and signal event preselection. The fit functions used in the analysis are verified on generated toy Monte Carlo data. Ranges of parameters, for which are these functions positive, are established and within this parametric space, the testing of possible intrinsic fit biases is evaluated. A dependence of the fit bias with respect to the collected number of events (expected in Run 2 as well as at HL-LHC) and to the different signal-to- background ratio is studied. The second part of the thesis deals with processing of raw reconstructed data from the detector into n-tuples resulting in a more compact dataset that would be used in the final analysis. Within the process, baseline cuts are applied in order to minimize size of final datasets by reducing...Ústav částicové a jaderné fyzikyInstitute of Particle and Nuclear PhysicsFaculty of Mathematics and PhysicsMatematicko-fyzikální fakult

Study of the rare B-meson decays with the ATLAS experiment

Rare B0 d → K∗ µ− µ+ decay is one of physics channels testing Stan- dard Model predictions at the ATLAS experiment. This work provides input to the future analysis of this rare decay in the data-taking period of Run 2. Speci- fically, in the work we were searching for the descriptions of the distributions of reconstructed invariant masses of the B and K∗ mesons and of the distribution of the decay angles for the signal decay and expected background processes. For the procedure of finding optimal description, a maximal likelihood method of fit was used. Search for the probability density functions was performed on simulated data containing signal decay and main the background channels (decays, which are misinterpreted by the detector like our signal decay). The background decays included Bs → φ(K+ K− )µ+ µ− , Λb → Λ(1520)(pK− )µ+ µ− and Λb → pK− µ+ µ− . The signal data were contamined with events, when detector misidentified the kaon and pion from the K∗ meson decay, which lead to modifications of the fit- ted parameters. These cases were separated and treated as special background process. In addition to the simulations, we analyzed the combinatorial background from the real data of Run 1, though only the angular distribution. Invariant mas- ses were not analyzed for their simplicity. We also show..

A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients

The p53 protein acts as a checkpoint in the cell cycle, either preventing or initiating apoptosis. Since cancer is the unchecked proliferation of cells, p53s role is critical. Thus, we have sought a link between the p53 polymorphisms and apoptosis. Wild-type p53 tumor suppressor gene exhibits several common single nucleotide polymorphisms (SNP) both in coding and non-coding regions. We focused on two of them, the p53 BstUI SNP on the fourth exon, and the p53 MspI SNP on the sixth intron. We investigated a presence of these two polymorphisms in relation to apoptosis of white blood cells in lung cancer patients and healthy controls. We found that both the p53 BstUI and the p53 MspI homozygous genotypes A2/A2 were associated with significantly higher content of apoptotic white blood cells in comparison to relevant A2/A1 heterozygous genotypes (P < 0.001, 0.05) in lung cancer patients. These observations suggest that the p53 BstUI and the p53 MspI SNPs may play a certain role in p53 dependent apoptotic pathway