779 research outputs found
Electron heating mechanisms in dual frequency capacitive discharges
We discuss electron heating mechanisms in the sheath regions of dual-frequency capacitive discharges, with the twin aims of identifying the dominant mechanisms and supplying closed-form expressions from which the heating power can be estimated. We show that the heating effect produced by either Ohmic or collisionless heating is much larger when the discharge is excited by a superposition of currents at two frequencies than if either current had acted alone. This coupling effect occurs because the lower frequency current, while not directly heating the electrons to any great extent, strongly affects the spatial structure of the discharge in the sheath regions
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The interest in relativistic beam-plasma instabilities has been greatly rejuvenated over the past two decades by novel concepts in laboratory and space plasmas. Recent advances in this long-standing field are here reviewed from both theoretical and numerical points of view. The primary focus is on the two-dimensional spectrum of unstable electromagnetic waves growing within relativistic, unmagnetized, and uniform electron beam-plasma systems. Although the goal is to provide a unified picture of all instability classes at play, emphasis is put on the potentially dominant waves propagating obliquely to the beam direction, which have received little attention over the years. First, the basic derivation of the general dielectric function of a kinetic relativistic plasma is recalled. Next, an overview of two-dimensional unstable spectra associated with various beam-plasma distribution functions is given. Both cold-fluid and kinetic linear theory results are reported, the latter being based on waterbag and Maxwell–Jüttner model distributions. The main properties of the competing modes (developing parallel, transverse, and oblique to the beam) are given, and their respective region of dominance in the system parameter space is explained. Later sections address particle-in-cell numerical simulations and the nonlinear evolution of multidimensional beam-plasma systems. The elementary structures generated by the various instability classes are first discussed in the case of reduced-geometry systems. Validation of linear theory is then illustrated in detail for large-scale systems, as is the multistaged character of the nonlinear phase. Finally, a collection of closely related beam-plasma problems involving additional physical effects is presented, and worthwhile directions of future research are outlined.Original Publication: Antoine Bret, Laurent Gremillet and Mark Eric Dieckmann, Multidimensional electron beam-plasma instabilities in the relativistic regime, 2010, Physics of Plasmas, (17), 12, 120501-1-120501-36. http://dx.doi.org/10.1063/1.3514586 Copyright: American Institute of Physics http://www.aip.org/</p
Ligand-binding propeties of the muscarinic acetylcholine receptor in mouse neuroblastoma cells
Radio-frequency discharges in Oxygen. Part 1: Modeling
In this series of three papers we present results from a combined
experimental and theoretical effort to quantitatively describe capacitively
coupled radio-frequency discharges in oxygen. The particle-in-cell Monte-Carlo
model on which the theoretical description is based will be described in the
present paper. It treats space charge fields and transport processes on an
equal footing with the most important plasma-chemical reactions. For given
external voltage and pressure, the model determines the electric potential
within the discharge and the distribution functions for electrons, negatively
charged atomic oxygen, and positively charged molecular oxygen. Previously used
scattering and reaction cross section data are critically assessed and in some
cases modified. To validate our model, we compare the densities in the bulk of
the discharge with experimental data and find good agreement, indicating that
essential aspects of an oxygen discharge are captured.Comment: 11 pages, 10 figure
Development of an Interpretive Simulation Tool for the Proton Radiography Technique
Proton radiography is a useful diagnostic of high energy density (HED)
plasmas under active theoretical and experimental development. In this paper we
describe a new simulation tool that interacts realistic laser-driven point-like
proton sources with three dimensional electromagnetic fields of arbitrary
strength and structure and synthesizes the associated high resolution proton
radiograph. The present tool's numerical approach captures all relevant physics
effects, including effects related to the formation of caustics.
Electromagnetic fields can be imported from PIC or hydrodynamic codes in a
streamlined fashion, and a library of electromagnetic field `primitives' is
also provided. This latter capability allows users to add a primitive, modify
the field strength, rotate a primitive, and so on, while quickly generating a
high resolution radiograph at each step. In this way, our tool enables the user
to deconstruct features in a radiograph and interpret them in connection to
specific underlying electromagnetic field elements. We show an example
application of the tool in connection to experimental observations of the
Weibel instability in counterstreaming plasmas, using particles
generated from a realistic laser-driven point-like proton source, imaging
fields which cover volumes of mm. Insights derived from this
application show that the tool can support understanding of HED plasmas.Comment: Figures and tables related to the Appendix are included in the
published journal articl
Generation of ultra-short light pulses by a rapidly ionizing thin foil
A thin and dense plasma layer is created when a sufficiently strong laser
pulse impinges on a solid target. The nonlinearity introduced by the
time-dependent electron density leads to the generation of harmonics. The pulse
duration of the harmonic radiation is related to the risetime of the electron
density and thus can be affected by the shape of the incident pulse and its
peak field strength. Results are presented from numerical
particle-in-cell-simulations of an intense laser pulse interacting with a thin
foil target. An analytical model which shows how the harmonics are created is
introduced. The proposed scheme might be a promising way towards the generation
of attosecond pulses.
PACS number(s): 52.40.Nk, 52.50.Jm, 52.65.RrComment: Second Revised Version, 13 pages (REVTeX), 3 figures in ps-format,
submitted for publication to Physical Review E, WWW:
http://www.physik.tu-darmstadt.de/tqe
Inequality, Fiscal Capacity and the Political Regime: Lessons from the Post-Communist Transition
Using panel data for twenty-seven post-communist economies between 1987-2003, we examine the nexus of relationships between inequality, fiscal capacity (defined as the ability to raise taxes efficiently) and the political regime. Investigating the impact of political reform we find that full political freedom is associated with lower levels of income inequality. Under more oligarchic (authoritarian) regimes, the level of inequality is conditioned by the state’s fiscal capacity. Specifically, oligarchic regimes with more developed fiscal systems are able to defend the prevailing vested interests at a lower cost in terms of social injustice. This empirical finding is consistent with the model developed by Acemoglu (2006). We also find that transition countries undertaking early macroeconomic stabilisation now enjoy lower levels of inequality; we confirm that education fosters equality and the suggestion of Commander et al (1999) that larger countries are prone to higher levels of inequality.http://deepblue.lib.umich.edu/bitstream/2027.42/57211/1/wp831 .pd
Performance-based financing as a health system reform : mapping the key dimensions for monitoring and evaluation
Peer reviewedPublisher PD
NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions
bS Supporting Information The enzyme dihydrofolate reductase (DHFR; 5,6,7,8-tetra-hydrofolate:NADPH oxidoreductase, EC 1.5.1.3) catalyzes the reduction of 7,8-dihydrofolate (DHF) to 5,6,7,8-tetrahydro-folate (THF) using NADPH as coenzyme.1 Since THF and its metabolites are precursors of purine and pyrimidine bases, the normal functioning of this enzyme is essential for proliferating cells. This makes DHFR an excellent target for antifolate drugs such as methotrexate (anticancer), pyrimethamine (antimalarial), and trimethoprim (antibacterial). Such agents act by inhibiting the enzyme in parasitic or malignant cells.1,2 The cooperative binding of ligands to DHFR plays an important role not only in the enzyme catalytic cycle (negative cooperativity in THF/ NADPH binding)3 but also in enzyme inhibition (positive cooperativity in antifolate/NADPH binding).4 The effects of positive cooperative binding in controlling enzyme inhibition ar
Investigation of the Chaotic Dynamics of an Electron Beam with a Virtual Cathode in an External Magnetic Field
The effect of the strength of the focusing magnetic field on chaotic dynamic
processes occurring inan electron beam with a virtual cathode, as well as on
the processes whereby the structures form in the beamand interact with each
other, is studied by means of two-dimensional numerical simulations based on
solving a self-consistent set of Vlasov-Maxwell equations. It is shown that, as
the focusing magnetic field is decreased,the dynamics of an electron beam with
a virtual cathode becomes more complicated due to the formation andinteraction
of spatio-temporal longitudinal and transverse structures in the interaction
region of a vircator. The optimum efficiency of the interaction of an electron
beam with the electromagnetic field of the vircator isachieved at a
comparatively weak external magnetic field and is determined by the
fundamentally two-dimensional nature of the motion of the beam electrons near
the virtual cathode.Comment: 12 pages, 8 figure
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