51 research outputs found

    Comment on "Atomic Scale Structure and Chemical Composition across Order-Disorder Interfaces"

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    Interfaces have long been known to be the key to many mechanical and electric properties. To nickel base superalloys which have perfect creep and fatigue properties and have been widely used as materials of turbine blades, interfaces determine the strengthening capacities in high temperature. By means of high resolution scanning transmission electron microscopy (HRSTEM) and 3D atom probe (3DAP) tomography, Srinivasan et al. proposed a new point that in nickel base superalloys there exist two different interfacial widths across the {\gamma}/{\gamma}' interface, one corresponding to an order-disorder transition, and the other to the composition transition. We argue about this conclusion in this comment

    Imaging and Pathological Features of Percutaneous Cryosurgery on Normal Lung Evaluated in a Porcine Model

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    Background and objective Lung cancer is one of the most commonly occurring malignancies and frequent causes of death in the world. Cryoablation is a safe and alternative treatment for unresectable lung cancer. Due to the lung being gas-containing organ and different from solid organs such as liver and pancreas, it is difficult to achieve the freezing range of beyond the tumor edge 1 cm safety border. The aim of this study is to examine the effect of different numbers of freeze cycles on the effectiveness of cryoablation on normal lung tissue and to create an operation guideline that gives the best effect. Methods Six healthy Tibetan miniature pigs were given a CT scan and histological investigation after percutaneous cryosurgery. Cryoablation was performed as 2 cycles of 10 min of active freezing in the left lung; each freeze followed by a 5 min thaw. In the right lung, we performed the same 2 cycles of 5 min of freezing followed by 5 min of thawing. However, for the right lung, we included a third cycle of consisting of 10 min of freezing followed by 5 min of thawing. Three cryoprobes were inserted into the left lung and three cryoprobes in the right lung per animal, one in the upper and two in the lower lobe, so as to be well away from each other. Comparison under the same experimental condition was necessary. During the experiment, observations were made regarding the imaging change of ice-ball. The lungs were removed postoperatively at 3 intervals: 4 h, 3 d of postoperation and 7 d of postoperation, respectively, to view microscopic and pathological change. Results The ice-ball grew gradually in relation to the increase in time, and the increase in number of cycles. The size of the cryolesion (hypothesis necrotic area) in specimens, over time, became larger in size than the size of the ice-ball during operation, regardless of whether 2 or 3 freeze-thaw cycles were performed. The area of necrosis was gradually increased over the course of time. The hypothesis necrotic area was equal to necrosis area 3 d after cryosurgery. Conclusion Percutaneous cryoablation of the lung can achieve complete ablation of target tissue. The freezing technique may be different depending on the individual circumstances of each tumor. In technology, 3 freeze-thaw cycles are recommended, and the range of cryoablation’s effective diameter may be not necessarily beyond the tumor edge at least 1 cm safe border during cryosurgery

    Determination of incommensurate modulated structure in Bi2Sr1.6La0.4CuO6+{\delta} by aberration-corrected transmission electron microscopy

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    Incommensurate modulated structure (IMS) in Bi2Sr1.6La0.4CuO6+{\delta} (BSLCO) has been studied by aberration corrected transmission electron microscopy in combination with high-dimensional (HD) space description. Two images in the negative Cs imaging (NCSI) and passive Cs imaging (PCSI) modes were deconvoluted, respectively. Similar results as to IMS have been obtained from two corresponding projected potential maps (PPMs), but meanwhile the size of dots representing atoms in the NCSI PPM is found to be smaller than that in PCSI one. Considering that size is one of influencing factors of precision, modulation functions for all unoverlapped atoms in BSLCO were determined based on the PPM obtained from the NCSI image in combination with HD space description

    Amphiphilic modification and asymmetric silica encapsulation of hydrophobic Au-Fe3O4 dumbbell nanoparticles

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    通讯作者地址: Zheng, NF (通讯作者),电子邮件地址: [email protected] facile method is developed for amphiphilic surface modification and asymmetric silica encapsulation of hydrophobic Au–Fe3O4 dumbbell nanoparticles. The obtained asymmetric Janus nanocomposites display tunable wettability, enhanced catalysis and better cell internalization as compared to those with complete silica encapsulation.MOST of China 2011CB932403 2014CB932004 NSFC of China 21131005 20925103 21333008 2102106

    Learning Optimal Strategies to Commit To

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    Over the past decades, various theories and algorithms have been developed under the framework of Stackelberg games and part of these innovations have been fielded under the scenarios of national security defenses and wildlife protections. However, one of the remaining difficulties in the literature is that most of theoretical works assume full information of the payoff matrices, while in applications, the leader often has no prior knowledge about the follower’s payoff matrix, but may gain information about the follower’s utility function through repeated interactions. In this paper, we study the problem of learning the optimal leader strategy in Stackelberg (security) games and develop novel algorithms as well as new hardness results

    Split-Spectrum Processing with Raised Cosine Filters of Constant Frequency-to-Bandwidth Ratio for L(0,2) Ultrasonic Guided Wave Testing in a Pipeline

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    Ultrasonic guided wave (UGW) nondestructive testing suffers from poor signal interpretation accuracy caused by the coherent noise that is related to dispersion, multi-mode and mode conversion. In order to split the L(0,2) UGW from the coherent noise, split-spectrum processing with raised cosine filters of constant frequency-to-bandwidth ratio (FBR-RC-SSP) is proposed. With the advantages of time domain resolution and frequency domain split, FBR-RC-SSP is studied based on time-frequency analysis using the chirplet transform, and the effects of filter parameters on signal-to-noise ratio gain (SNRG) and defect-to-coherent noise gain (DCRG) are explained. The excellent effects of eliminating the coherent noise and improving the signal resolution in FBR-RC-SSP are reported by the validation of synthesized, simulated and experimental UGW signals, of which the average SNRG and DCRG are 22.92% and 23.71% higher than those of traditional SSP using Gaussian filters, and it has the potential to locate and characterize defects in further UGW testing research
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