32 research outputs found

    A 2500 year old pseudo shell midden on Longreach Bay, Rottnest Island, Western Australia.

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    On several occasions during the past decade, Perth-based and occasional visiting Quaternary researchers have examined possible prehistoric human occupation sites on Rottnest Island, 20 km west of Fremantle, WA. The following describes findings from recent investigations of possible prehistoric midden material from a site on Longreach Bay, Rottnest Island

    Methodologies for processing plant material into acceptable food on a small scale

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    Based on the Controlled Environment Life Support System (CELSS) production of only four crops, wheat, white potatoes, soybeans, and sweet potatoes; a crew size of twelve; a daily planting/harvesting regimen; and zero-gravity conditions, estimates were made on the quantity of food that would need to be grown to provide adequate nutrition; and the corresponding amount of biomass that would result. Projections were made of the various types of products that could be made from these crops, the unit operations that would be involved, and what menu capability these products could provide. Equipment requirements to perform these unit operations were screened to identify commercially available units capable of operating (or being modified to operate) under CELSS/zero-gravity conditions. Concept designs were developed for those equipment needs for which no suitable units were commercially available. Prototypes of selected concept designs were constructed and tested on a laboratory scale, as were selected commercially available units. This report discusses the practical considerations taken into account in the various design alternatives, some of the many product/process factors that relate to equipment development, and automation alternatives. Recommendations are made on both general and specific areas in which it was felt additional investigation would benefit CELSS missions

    Identification d’un nouveau jalon relatif aux nécropoles de l’Epipaléolithique du Maghreb : la grotte de Ghar Kahal à Tarhemt, province de Tétouan

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    Les travaux conduits dans le cadre de la coopération franco-marocaine sur le site de Ghar Kahal, de 1985 à 1988, puis sur les collections entre 1991 et 2009, ont permis de réévaluer les conceptions anciennes qui considéraient ce site comme un point mineur participant du peuplement épipaléolithique, mais, en revanche, comme une illustration privilégiée de la séquence régionale couvrant le Néolithique ancien et le Campaniforme. Des perturbations anthropiques importantes en affectent le remplissage et invalident la séquence chronostratigraphique du Néolithique théorisée en 1958 par Tarradell. En réappréciant l’importance de l’occupation épipaléolithique et en établissant un lien objectif entre celle-ci et la présence d’une nécropole organisée datée par AMS à la charnière des onzième et douzième millénaire avant notre ère, nos observations permettent de replacer le site au sein d’un ensemble culturel cohérent témoignant d’une occupation humaine du Maroc septentrional plus dense qu’elle n’avait été initialement perçue

    Human Peripheral Blood Mononuclear Cells Exhibit Heterogeneous CD52 Expression Levels and Show Differential Sensitivity to Alemtuzumab Mediated Cytolysis

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    Alemtuzumab is a monoclonal antibody that targets cell surface CD52 and is effective in depleting lymphocytes by cytolytic effects in vivo. Although the cytolytic effects of alemtuzumab are dependent on the density of CD52 antigen on cells, there is scant information regarding the expression levels of CD52 on different cell types. In this study, CD52 expression was assessed on phenotypically distinct subsets of lymphoid and myeloid cells in peripheral blood mononuclear cells (PBMCs) from normal donors. Results demonstrate that subsets of PBMCs express differing levels of CD52. Quantitative analysis showed that memory B cells and myeloid dendritic cells (mDCs) display the highest number while natural killer (NK) cells, plasmacytoid dendritic cells (pDCs) and basophils have the lowest number of CD52 molecules per cell amongst lymphoid and myeloid cell populations respectively. Results of complement dependent cytolysis (CDC) studies indicated that alemtuzumab mediated profound cytolytic effects on B and T cells with minimal effect on NK cells, basophils and pDCs, correlating with the density of CD52 on these cells. Interestingly, despite high CD52 levels, mDCs and monocytes were less susceptible to alemtuzumab-mediated CDC indicating that antigen density alone does not define susceptibility. Additional studies indicated that higher expression levels of complement inhibitory proteins (CIPs) on these cells partially contributes to their resistance to alemtuzumab mediated CDC. These results indicate that alemtuzumab is most effective in depleting cells of the adaptive immune system while leaving innate immune cells relatively intact

    Humans and volcanoes in Australia and New Guinea/Hommes et volcans en Australie et en Nouvelle Guinée

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    This paper speculates on the possible role of volcanoes in mythological representations of the human capture of fire as a resource.Les auteurs examinent la question du volcanisme contemporain de la Préhistoire récente d'Australie et de Nouvelle Guinée par le biais des témoignages conservés par la mémoire aborigène sous la forme de mythes d'aquisition du feu.Bindon Peter, Raynal Jean Paul. Humans and volcanoes in Australia and New Guinea/Hommes et volcans en Australie et en Nouvelle Guinée. In: Quaternaire, vol. 9, n°1, 1998. Hommes et volcans. pp. 71-75

    Dentate and Related Stone Biface Points from Northern Australia

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    Volume: 12Start Page: 89End Page: 9

    Humans and volcanoes in Australia and New Guinea

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    This paper speculates on the possible role of volcanoes in mythological representations of the human capture of fire as a resource
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