Buffer gas induced collision shift for the 88^{88}Sr 1S0−3P1\bf{^1S_0-^3P_1} clock transition

Precision saturation spectroscopy of the $^{88}{\rm Sr} ^1S_0-^3P_1$ is performed in a vapor cell filled with various rare gas including He, Ne, Ar, and Xe. By continuously calibrating the absolute frequency of the probe laser, buffer gas induced collision shifts of $\sim$kHz are detected with gas pressure of 1-20 mTorr. Helium gave the largest fractional shift of $1.6 \times 10^{-9} {\rm Torr}^{-1}$. Comparing with a simple impact calculation and a Doppler-limited experiment of Holtgrave and Wolf [Phys. Rev. A {\bf 72}, 012711 (2005)], our results show larger broadening and smaller shifting coefficient, indicating effective atomic loss due to velocity changing collisions. The applicability of the result to the $^1S_0-^3P_0$ optical lattice clock transition is also discussed

Use of information technology to increase economic efficiency and credibility in public administration in the context of digitization

Purpose: The article analyzes the use of information technologies to increase the level of economic efficiency and trust in public administration in Ukraine. Design/Methodology/Approach: We use the concept of digital management for the purpose of integrated interaction of municipal and state structures with business, civil society institutions and the population. Findings: The conducted research concludes the active digital transformation of public administration in Ukraine. The following trends in the use of information technology are identified: the development of institutional support; the creation of analytical portals for ensuring public control; the level of accountability, transparency, accountability of the activity of civil servants; the implementation of e-government projects; the changing philosophy of development of electronic services. Practical Implications: The concept of state policy in the field of digital infrastructure was developed on the basis of a multi-stakeholder approach according to which the main purpose of the state bodies is to identify, prioritize, harmonize and satisfy the stakeholders. Originality/Value: In this article, we show the level of individual regions in Ukraine where there is uneven implementation and use of e-learning tools management.peer-reviewe

Parameterised Geant4 simulation for total body PET research

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development for total-body PET imaging of humans. This variety, in particular the variation in axial field-of-view (aFOV), motivates a need to compare the performance of these devices in a consistent simulated environment. We present an open-source Geant4 simulation package that allows variation of relevant parameters such as the detector aFOV and the tracer radioisotope from the command line. Two simplified detector geometries based on the Siemens Biograph Vision Quadra and United Imaging uEXPLORER models are supported with variable granularity. The intrinsic radioactivity of the detector crystals is fully simulated. The simulation can be viewed with the built-in GUI, and the results are saved in a plain text format for easy analysis. Example Python analysis code is provided with the simulation, demonstrating calculation of the noise equivalent count rate (NECR) figure of merit using an approximation to the NEMA NU 2-2012 standard method. A good agreement between the simulated count rate performance and experimental data is observed for both geometries. The differences in results are attributed to simplifications in the simulation code, namely not accounting for the light-collection efficiency or readout dead-time. We demonstrate the importance of assessing the scanner performance using appropriate phantom length which significantly affects the obtained results. A dependence between the detector aFOV and the length of the source, with peak NECR plateauing as the detector extends beyond the region of interest is also presented.Comment: 13 pages in total, 6 figure

Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes.

This is the final version of the article. Available from Rockefeller University Press via the DOI in this record.Bidirectional membrane trafficking along microtubules is mediated by kinesin-1, kinesin-3, and dynein. Several organelle-bound adapters for kinesin-1 and dynein have been reported that orchestrate their opposing activity. However, the coordination of kinesin-3/dynein-mediated transport is not understood. In this paper, we report that a Hook protein, Hok1, is essential for kinesin-3- and dynein-dependent early endosome (EE) motility in the fungus Ustilago maydis. Hok1 binds to EEs via its C-terminal region, where it forms a complex with homologues of human fused toes (FTS) and its interactor FTS- and Hook-interacting protein. A highly conserved N-terminal region is required to bind dynein and kinesin-3 to EEs. To change the direction of EE transport, kinesin-3 is released from organelles, and dynein binds subsequently. A chimaera of human Hook3 and Hok1 rescues the hok1 mutant phenotype, suggesting functional conservation between humans and fungi. We conclude that Hok1 is part of an evolutionarily conserved protein complex that regulates bidirectional EE trafficking by controlling attachment of both kinesin-3 and dynein.This work was supported by Wellcome Trust (097835/Z/11/Z) and the Biotechnology and Biological Sciences Research Council (BB/J009903/1)

An Overview of the Canadian Health Care System

The Canadian health care system is a publicly financed system administered by ten provincial and three territorial governments. The purpose of this article is to provide an overview of the universal health care system in Canada, including its history, the health status of Canadians, health care funding and spending, and health research and data collection. Health care spending in Canada amounts to 11.6% of the country’s gross domestic product and is estimated to have been $200.5 billion Canadian dollars in 2011. Hospitals account for the largest source of health care spending (29%), followed by drugs (16%) and physician spending (14%). Of the total health care spending, 70% is paid for by the public system. Due to the Canadian population being covered by the universal health care system, health data are being collected and can be used to monitor the health care system and inform evidence-based medicine

Perception of Food Security at Household Level by Students of the University of Warmia and Mazury in Olsztyn

Subject and purpose of work: The aim of this paper was to identify how students of the University of Warmia and Mazury in Olsztyn perceived food security at household level. It was verified whether selected students were able to define properly the terms connected with the topic and how food safety was assessed. Materials and methods: The survey was performed using a questionnaire as the research tool. The survey was conducted at three faculties in the following courses of studies: economics, law, and bioengineering of food production. Statistical data were included. Results: Most of the respondents considered food security at household level in Poland to be at a satisfying level. In most respondent’s households, expenditure on food in relation to income was at a higher level than the national average. Conclusions: Food security in the households of the surveyed students was ensured. The economic availability of food in the analysed households was good, as most respondents were able to purchase high quality food products

The Current State and Necessity of Transformation of the Management System of Educational Establishments in Ukraine at the Local Level

The integration of Ukraine into the European community creates the necessity to carry out scientific research regarding the reformation of public management systems and to introduce principles of state management to management systems. The implementation of administrative reform and the realization of innovative systems of local self-government with elements of state management at local level will foster good conditions for intellectual, professional, and spiritual development in all individuals, and should become a state priority. Therefore, the peculiarities of state management of the educational system at the local level under conditions of education modernization, identification, and the prevention of negative aspects of this process are studied in this article. In regards to state management, the current state of the management system of educational establishments at local level is analyzed, and recommendations concerning changes to this system are proposed according to legislation. It has been found that the reformation of the system of local self-government opens up opportunities for the improvement of the state management model, the implementation of state management principles, and creates good conditions for regional development.Ukrainos integracija į Europos bendruomenę lemia būtinybę atlikti mokslinius tyrimus pertvarkant viešojo valdymo sistemą ir įvesti valstybės valdymo principus valdymo sistemai. Administracinės reformos įgyvendinimas, novatoriškos vietos savivaldos sistemos įgyvendinimas su valstybės valdymo elementais vietos lygiu leis sukurti geras sąlygas kiekvieno žmogaus intelektualiam, profesiniam ir dvasiniam vystymuisi, ir tai turėtų tapti valstybės prioritetu. Todėl darbe nagrinėjami švietimo sistemos valstybinio valdymo vietos lygmeniu ypatumai švietimo modernizavimo sąlygomis ir neigiamų šio proceso aspektų nustatymas bei prevencija. Kalbant apie valstybės valdymą, analizuojama dabartinė švietimo įstaigų valdymo sistema vietos lygmeniu, o straipsnyje pateikiamos rekomendacijos dėl šios sistemos keitimui pagal teisės aktus. Nustatyta, kad vietos savivaldos sistemos pertvarkymas atveria galimybes tobulinti valstybės valdymo modelį, įgyvendinti valstybės valdymo principus ir sudaro geras sąlygas regiono plėtrai

Strontium optical lattice clocks for practical realization of the metre and secondary representation of the second

We present a system of two independent strontium optical lattice standards probed with a single shared ultra-narrow laser. The absolute frequency of the clocks can be verified by the use of Er:fiber optical frequency comb with the GPS-disciplined Rb frequency standard. We report hertz-level spectroscopy of the clock line and measurements of frequency stability of the two strontium optical lattice clocks.Comment: This is an author-created, un-copyedited version of an article accepted for publication in Meas. Sci. Technol. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at doi:10.1088/0957-0233/26/7/07520

Measurement and calculation of CO (7-0) overtone line intensities

Intensities of 14 lines in the sixth overtone (7-0) band of carbon monoxide (12C16O) are measured in the visible range between 14 300 and 14 500 cm-1 using a frequency-stabilized cavity ring-down spectrometer. This is the first observation of such a high and weak overtone spectrum of the CO molecule. A theoretical model is constructed and tested based on the use of a high accuracy ab initio dipole moment curve and a semi-empirical potential energy curve. Accurate studies of high overtone transitions provide a challenge to both experiment and theory as the lines are very weak: below 2 × 10-29 cm molecule-1 at 296 K. Agreement between theory and experiment within the experimental uncertainty of a few percent is obtained. However, this agreement is only achieved after issues with the stability of the Davidson correction to the multi-reference configuration interaction calculations are addressed