54 research outputs found

    Spoken word production: Processes and potential breakdown

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    Introduction: The processes of spoken word production have been a focus of interest for decades and this research has been summarised in several reviews (e.g., Friedmann, Biran, & Dotan, 2013; Nickels, 1997, 2001a,b; Wilshire, 2008). However, many questions remain unanswered and consequently spoken word production remains an area of research interest, informed by data from unimpaired and impaired adult language, as well as language development. Several theories of spoken language production have been proposed over the last half century, each differing slightly in levels of representation, processing steps, and activation flow. In this chapter, we focus on four of the most influential theories of spoken language production

    Garlic and ginger are not like apples and oranges: Effects of mass/count information on the production of noun phrases in English

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    In this study a picture–word interference paradigm was used to investigate how grammatical mass/count information is processed during noun phrase production in English. Theories of lexical processing distinguish between two different types of lexical–syntactic information: variable extrinsic lexical–syntactic features, such as number (singular, plural), and fixed intrinsic lexical–syntactic properties, such as grammatical gender (e.g., masculine, feminine). Previous research using the picture–word interference paradigm has found effects of distractor lexical–syntactic congruency for grammatical gender but no congruency effects for number. We used this phenomenon to investigate whether mass/count information is processed similarly to grammatical gender. In two experiments, participants named pictures of mass or count objects using determiner noun phrases (e.g., Experiment 1 with mass and plural count nouns: “not muchmass ricemass”, “not manycount pegscount”; Experiment 2 with mass and singular count nouns: “some ricemass”, “a pegcount”), while ignoring distractors that were countability congruent or incongruent nouns. The results revealed a countability congruency effect for mass and plural count nouns in Experiment 1 and for singular count nouns, but not mass nouns in Experiment 2. This is similar to grammatical gender suggesting that countability processing is predominantly driven by a noun’s lexical–syntactic information. © 2017 The Experimental Psychology Societ

    Syllable frequency effects in immediate but not delayed syllable naming in English

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    <p>Syllable frequency effects in production tasks are interpreted as evidence that speakers retrieve precompiled articulatory programs for high frequency syllables from a mental syllabary. They have not been found reliably in English, nor isolated to the phonetic encoding processes during which the syllabary is thought to be accessed. In this experiment, 48 participants produced matched high- and novel/low-frequency syllables in a near-replication of Laganaro and Alario’s [(2006) On the locus of the syllable frequency effect in speech production. <i>Journal of Memory and Language, 55</i>(2), 198–196, <a href="http://dx.doi.org/10.1016/j.jml.2006.05.001" target="_blank">http://dx.doi.org/10.1016/j.jml.2006.05.001</a>] production conditions: immediate naming, naming following an unfilled delay, and naming after delay filled by concurrent articulation. Immediate naming was faster for high frequency syllables, demonstrating a robust syllable frequency effect in English. There was no high frequency advantage in either delayed naming condition, leaving open the question of whether syllable frequency effects arise during phonological or phonetic encoding.</p

    No meditation-related changes in the auditory N1 during first-time meditation

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    Recent studies link meditation expertise with enhanced low-level attention, measured through auditory event-related potentials (ERPs). In this study, we tested the reliability and validity of a recent finding that the N1 ERP in first-time meditators is smaller during meditation than non-meditation – an effect not present in long-term meditators. In the first experiment, we replicated the finding in first-time meditators. In two subsequent experiments, we discovered that this finding was not due to stimulus-related instructions, but was explained by an effect of the order of conditions. Extended exposure to the same tones has been linked with N1 decrement in other studies, and may explain N1 decrement across our two conditions. We give examples of existing meditation and ERP studies that may include similar condition order effects. The role of condition order among first-time meditators in this study indicates the importance of counterbalancing meditation and non-mediation conditions in meditation studies that use event-related potentials

    Meditation and auditory attention: An ERP study of meditators and non-meditators

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    The findings of a study by Cahn and Polich (2009) suggests that there is an effect of a meditative state on three event-related potential (ERP) brain markers of “low-level” auditory attention (i.e., acoustic representations in sensory memory) in expert meditators: the N1, the P2, and the P3a. The current study built on these findings by examining trait and state effects of meditation on the passive auditory mismatch negativity (MMN), N1, and P2 ERPs. We found that the MMN was significantly larger in meditators than non-meditators regardless of whether they were meditating or not (a trait effect), and that N1 amplitude was significantly attenuated during meditation in non-meditators but not expert meditators (an interaction between trait and state). These outcomes suggest that low-level attention is superior in long-term meditators in general. In contrast, low-level attention is reduced in non-meditators when they are asked to meditate for the first time, possibly due to auditory fatigue or cognitive overload

    Advanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients

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    The awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can progress to chronicity in immunocompromised individuals. Persistent infection and antiviral therapy can select HEV-3 variants; however, the spectrum and occurrence of HEV-3 variants is underreported. To gain in-depth insights into the viral population and to perform detailed characterization of viral genomes, we used a new approach combining long-range PCR with next-generation and third-generation sequencing which allowed near full-length sequencing of HEV-3 genomes. Furthermore, we developed a targeted ultra-deep sequencing approach to assess the dynamics of clinically relevant mutations in the RdRp-region and to detect insertions in the HVR-domain in the HEV genomes. Using this new approach, we not only identified several insertions of human (AHNAK, RPL18) and viral origin (RdRp-derived) in the HVR-region isolated from an exemplary sample but detected a variant containing two different insertions simultaneously (AHNAK- and RdRp-derived). This finding is the first HEV-variant recognized as such showing various insertions in the HVR-domain. Thus, this molecular approach will add incrementally to our current knowledge of the HEV-genome organization and pathogenesis in chronic hepatitis E.Peer Reviewe
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